Melissa M. Hudson
Because of remarkable progress in therapy, long-term survival is expected for 80% of children and adolescents diagnosed with cancer. Infertility remains one of the most common and life-altering complications experienced by adults treated for cancer during childhood. Surgery, radiation, or chemothera...
Irina Neganova, Majlinda Lako
It is well known that G1 to S phase transition is tightly regulated by the expression and phosphorylation of a number of well-characterized cyclins, cyclin-dependent kinases and members of the retinoblastoma gene family. In this review we discuss the role of these components in regulation of G1 to S...
Masaki Satō, Mitsuyo Matsumoto, Yuriko Saiki, Mahabub Alam et al.
Abstract Pancreatic ductal adenocarcinoma (PDAC) is among the cancers with the poorest prognoses due to its highly malignant features. BTB and CNC homology 1 (BACH1) has been implicated in RAS-driven tumor formation. We focused on the role of BACH1 in PDAC, more than 90% of which have KRAS mutation....
Bettina E. Mucha, Fatih Özaltın, Bernward Hinkes, K Hasselbacher et al.
Primary steroid-resistant nephrotic syndrome (SRNS) is characterized by childhood onset of proteinuria and progression to end-stage renal disease. Approximately 10-25% of familial and sporadic cases are caused by mutations in NPHS2 (podocin). Mutations in exons 8 and 9 of the WT1 gene have been foun...
Michael A.S. Jewett, Ricardo Rendon, Louis Lacombe, Pierre I. Karakiewicz et al.
Md. Ismail Hosen, Nathalie Forey, Geoffroy Durand, Catherine Voegele et al.
Somatic mutations in the telomerase reverse transcriptase (TERT) promoter regions are frequent events in urothelial cancer (UC) and their detection in urine (supernatant cell-free DNA or DNA from exfoliated cells) could serve as putative non-invasive biomarkers for UC detection and monitoring. Howev...
Tadahiro Nagaoka, Ayumu Inutsuka, Khadiza Begum, Khandakar musabbir bin hafiz et al.
E-cadherin belongs to the classic cadherin subfamily of calcium-dependent cell adhesion molecules and is crucial for the formation and function of epithelial adherens junctions. In this study, we demonstrate that Vangl2, a vertebrate regulator of planar cell polarity (PCP), controls E-cadherin in ep...
Dessie Salilew‐Wondim, Dawit Tesfaye, M.M. Hossain, Eva Held et al.
In the present study, we used the global transcriptome profile approach to identify dysregulated genes, molecular pathways, and molecular functional alterations in bovine placentas derived from somatic cell nuclear transfer (SCNT) and in vitro embryo production (IVP) pregnancies compared with their ...
Borhan Uddin, Patrick Partscht, Nan‐Peng Chen, Annett Neuner et al.
CDC14A codes for a conserved proline‐directed phosphatase, and mutations in the gene are associated with autosomal‐recessive severe to profound deafness, due to defective kinocilia. A role of CDC14A in cilia formation has also been described in other organisms. However, how human CDC14A impacts on c...
S. A. Masudul Hoque, Tomoko Kawai, Zhendong Zhu, Masayuki Shimada
culture of GCs in DMEM medium supplemented with FSH, testosterone, and serum and containing different glucose concentrations with or without d-chloramphenicol (CRP) for 24 hours. GC proliferation and ATP production were observed to be independent of glucose concentration. Furthermore, FSH-induced mi...
Farhadul Islam, Vinod Gopalan, Simon Law, Johnny Tang et al.
Family with sequence similarity 134, member B (FAM134B) is an autophagy regulator of endoplasmic reticulum first discovered to be involved in the pathogenesis of esophageal squamous cell carcinoma (ESCC). The present study examined the functional behavior of FAM134B in cancer cells and the associati...
Oswald S. Lowsley
No AccessJournal of Urology1 May 1952Surgery of the Horseshoe Kidney Oswald S. Lowsley Oswald S. LowsleyOswald S. Lowsley More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)68389-7AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsRep...
Gordan Vujanić
A unilateral teratoid Wilms' tumor was removed 2.5 weeks after the institution of chemotherapy. Teratoid Wilms' tumor is an extremely rare renal tumor, and only four cases, all bilateral, have been reported. Because of the finding of deep cortical intralobar nephroblastomatosis, strongly associated ...
Ashutosh Das, Mishuk Shaha, Mukta Das Gupta, Avijit Dutta et al.
Goat farming in Bangladesh is primarily centred on indigenous Black Bengal goat, a highly prolific breed. Searching for genetic markers associated with prolificacy in this breed is vital for the country’s goat breeding industry. However, there are no reports on polymorphisms associated with the fert...
José Luis Cano-Peñalver, Mercedes Griera, Isabel Serrano, Diego Rodrı́guez-Puyol et al.
One of the clinical alterations observed in chronic renal disease (CRD) is the impaired urine concentration, known as diabetes insipidus (DI). Tubulointerstitial fibrosis of the kidney is also a pathological finding observed in CRD and involves composition of extracellular matrix (ECM). However, an ...