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Field: Transgenic Plants and Applications

Bioactive Secondary Metabolites from Plant Sources: Types, Synthesis, and Their Therapeutic Uses

Verified

Baan Munim Twaij, Md. Nazmul Hasan

Journal: International Journal of Plant Biology
Year: 2022
Citations: 401

Plants are the source of various photochemicals; metabolites are used in medicinal and environmental sectors as well as being widely used in commercial and pharmaceutical products. Although they produce a number of medicinal products, either already on the market or under trial, the amounts obtained...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Protein disulfide engineering

Verified

Alan A. Dombkowski, Kazi Zakia Sultana, Douglas B. Craig

Journal: FEBS LettersYear: 2013Citations: 286

Improving the stability of proteins is an important goal in many biomedical and industrial applications. A logical approach is to emulate stabilizing molecular interactions found in nature. Disulfide bonds are covalent interactions that provide substantial stability to many proteins and conform to w...

Life SciencesBiochemistry, Genetics and Molecular BiologyBiotechnology
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Natural products and their derivatives against coronavirus: A review of the non‐clinical and pre‐clinical data

Verified

Muhammad Torequl Islam, Chandan Kumar Sarkar, Dina M. El‐Kersh, Sarmin Jamaddar et al.

Journal: Phytotherapy ResearchYear: 2020Citations: 236

Several corona viral infections have created serious threats in the last couple of decades claiming the death of thousands of human beings. Recently, corona viral epidemic raised the issue of developing effective antiviral agents at the earliest to prevent further losses. Natural products have alway...

Health SciencesMedicineComplementary and alternative medicine
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Production of biomass and useful compounds from adventitious roots of high-value added medicinal plants using bioreactor

Verified

Md. Abdullahil Baque, Sang-Hyun Moh, Eunjung Lee, Jian‐Jiang Zhong et al.

Journal: Biotechnology AdvancesYear: 2011Citations: 198

The increasing global demand for biomass of medicinal plant resources reflects the issues and crisis created by diminishing renewable resources and increasing consumer populations. Moreover, diverse usage of plants and reduced land for cultivation in the world accelerated the deficiency of plant res...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Biology
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Plants Metabolites: Possibility of Natural Therapeutics Against the COVID-19 Pandemic

Verified

Farhana Rumzum Bhuiyan, Sabbir Howlader, Topu Raihan, Mahmudul Hasan

Journal: Frontiers in MedicineYear: 2020Citations: 173

COVID-19, a disease induced by SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus-2), has been the cause of a worldwide pandemic. Though extensive research works have been reported in recent days on the development of effective therapeutics against this global health crisis, there is still no...

Life SciencesAgricultural and Biological SciencesFood ScienceOpen Access
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Traditional Herbal Medicines, Bioactive Metabolites, and Plant Products Against COVID-19: Update on Clinical Trials and Mechanism of Actions

Verified

Safaet Alam, Md. Moklesur Rahman Sarker, Sadia Afrin, Fahmida Tasnim Richi et al.

Journal: Frontiers in PharmacologyYear: 2021Citations: 143

SARS-CoV-2 is the latest worldwide pandemic declared by the World Health Organization and there is no established anti-COVID-19 drug to combat this notorious situation except some recently approved vaccines. By affecting the global public health sector, this viral infection has created a disastrous ...

Life SciencesBiochemistry, Genetics and Molecular BiologyBiotechnologyOpen Access
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Phytochemicals from Plant Foods as Potential Source of Antiviral Agents: An Overview

Verified

Tapan Behl, Gabriele Rocchetti, Swati Chadha, Gökhan Zengin et al.

Journal: PharmaceuticalsYear: 2021Citations: 132

To date, the leading causes of mortality and morbidity worldwide include viral infections, such as Ebola, influenza virus, acquired immunodeficiency syndrome (AIDS), severe acute respiratory syndrome (SARS) and recently COVID-19 disease, caused by the SARS-CoV-2 virus. Currently, we can count on a n...

Life SciencesBiochemistry, Genetics and Molecular BiologyBiotechnologyOpen Access
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Molecular and genetic characterization of elite transgenic rice plants produced by electric-discharge particle acceleration

Verified

J. C. Cooley, Tameria L. Ford, Paul Christou

Journal: Theoretical and Applied GeneticsYear: 1995Citations: 109

The recovery of transgenic rice plants expressing a number of exogenous genes was reported previously. Using immature embryo explants as the target tissue, plasmids containing both selectable and screenable marker genes were introduced into elite rice varieties via electric-discharge particle accele...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Biology
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Re-utilization of germinal centers in multiple Peyer's patches results in highly synchronized, oligoclonal, and affinity-matured gut IgA responses

Verified

Peter Bergqvist, Anneli Stensson, Lena Hazanov, Anna Holmberg et al.

Journal: Mucosal ImmunologyYear: 2012Citations: 100

Whereas gut IgA responses to the microbiota may be multi-centered and diverse, little is known about IgA responses to T-cell-dependent antigens following oral immunizations. Using a novel approach, gut IgA responses to oral hapten (4-hydroxy-3-nitrophenyl)acetyl-cholera toxin (NP-CT) conjugates were...

Life SciencesBiochemistry, Genetics and Molecular BiologyBiotechnology
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Immunoinformatics-guided designing of epitope-based subunit vaccines against the SARS Coronavirus-2 (SARS-CoV-2)

Verified

Bishajit Sarkar, Md. Asad Ullah, Fatema Tuz Johora, Masuma Afrin Taniya et al.

Journal: ImmunobiologyYear: 2020Citations: 96

SARS Coronavirus-2 (SARS-CoV-2) pandemic has become a global issue which has raised the concern of scientific community to design and discover a counter-measure against this deadly virus. So far, the pandemic has caused the death of hundreds of thousands of people upon infection and spreading. To da...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Bacilli as sources of agrobiotechnology: recent advances and future directions

Verified

Zerihun T. Dame, Mahfuzur Rahman, Tofazzal Islam

Journal: Green Chemistry Letters and ReviewsYear: 2021Citations: 89

The group bacilli represent the Gram-positive ubiquitous spore-forming bacteria. Their diversity, versatility and the ability of producing diverse secondary metabolites including enzymes created enormous potential for applications in agriculture, biotechnology, environment and medicine. The bacilli ...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Development and evaluation of in vitro somaclonal variation in strawberry for improved horticultural traits

Verified

M. K. Biswas, Manjul Dutt, Uthpal Krishna Roy, R. Islam et al.

Journal: Scientia HorticulturaeYear: 2009Citations: 86
Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Biology
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An updated review on lumpy skin disease: a perspective of Southeast Asian countries

Verified

Moumita Das, Md. Shahidur Rahman Chowdhury, Sharmin Akter, Apurbo Kumar Mondal et al.

Journal: Journal of Advanced Biotechnology and Experimental TherapeuticsYear: 2021Citations: 82

In recent days, Lumpy Skin Disease (LSD) has been portrayed as a terrifying threat to cattle in Southeast Asia. A lump like nodules in the external skin and mucus membrane with fever and swollen lymph nodes are the preliminary noticeable signs for this devastating disease. It is commonly an arthropo...

Life SciencesImmunology and MicrobiologyVirologyOpen Access
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In vitro callus induction and plantlet regeneration of Achyranthes aspera L., a high value medicinal plant

Verified

Monokesh K. Sen, Shamima Nasrin, Shahedur Rahman, Abu Hena Mostofa Jamal

Journal: Asian Pacific Journal of Tropical BiomedicineYear: 2013Citations: 76

OBJECTIVE: To study callus induction from different explants (internode, leaf, root) and in vitro plantlets propagation from medicinally important plant Achyranthes aspera L. METHODS: Sterilized explants were prepared by using 0.1% HgCl2 and 0.5% Bavistin and callus was obtained when cultured onto M...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Advances in Computational and Bioinformatics Tools and Databases for Designing and Developing a Multi-Epitope-Based Peptide Vaccine

Verified

Mohammad Mahfuz Ali Khan Shawan, Ashish Ranjan Sharma, Sajal Kumar Halder, Tawsif Al Arian et al.

Journal: International Journal of Peptide Research and TherapeuticsYear: 2023Citations: 72

A vaccine is defined as a biologic preparation that trains the immune system, boosts immunity, and protects against a deadly microbial infection. They have been used for centuries to combat a variety of contagious illnesses by means of subsiding the disease burden as well as eradicating the disease....

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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