Elizabeth A. Ashley, Mehul Dhorda, Rick M. Fairhurst, Chanaki Amaratunga et al.
BACKGROUND: Artemisinin resistance in Plasmodium falciparum has emerged in Southeast Asia and now poses a threat to the control and elimination of malaria. Mapping the geographic extent of resistance is essential for planning containment and elimination strategies. METHODS: Between May 2011 and Apri...
A H Smith, Elena O. Lingas, Mizanur Rahman
The contamination of groundwater by arsenic in Bangladesh is the largest poisoning of a population in history, with millions of people exposed. This paper describes the history of the discovery of arsenic in drinking-water in Bangladesh and recommends intervention strategies. Tube-wells were install...
Helen Noble, Joanna Smith
Evaluating the quality of research is essential if findings are to be utilised in practice and incorporated into care delivery. In a previous article we explored 'bias' across research designs and outlined strategies to minimise bias. Concepts such as reliability, validity and generalisability typic...
Sergei Põlme, Kessy Abarenkov, R. Henrik Nilsson, Björn D. Lindahl et al.
TEST 02 - Elsevier's Scopus, the largest abstract and citation database of peer-reviewed literature. Search and access research from the science, technology, medicine, social sciences and arts and humanities fields.
Helge Bruelheide, Jürgen Dengler, Oliver Purschke, Jonathan Lenoir et al.
Plant functional traits directly affect ecosystem functions. At the species level, trait combinations depend on trade-offs representing different ecological strategies, but at the community level trait combinations are expected to be decoupled from these trade-offs because different strategies can f...
Joel B. Smith, Stephen H. Schneider, Michael Oppenheimer, Gary Yohe et al.
Article 2 of the United Nations Framework Convention on Climate Change [United Nations (1992) http://unfccc.int/resource/docs/convkp/conveng.pdf. Accessed February 9, 2009] commits signatory nations to stabilizing greenhouse gas concentrations in the atmosphere at a level that "would prevent dangero...
Jason Corburn, David Vlahov, Blessing Mberu, Lee W. Riley et al.
The informal settlements of the Global South are the least prepared for the pandemic of COVID-19 since basic needs such as water, toilets, sewers, drainage, waste collection, and secure and adequate housing are already in short supply or non-existent. Further, space constraints, violence, and overcr...
Philip J. Ashworth, Sean J. Bennett, Jim Best, Stuart McLelland
List of Contributors. Acknowledgements. Coherent Flow Structures in Smooth-wall Turbulent Boundaary Layers: Facts, Mechnaisms and Speculations (C. Smith). Generalized Scaling of Coherent Bursting Structures in the Near-wall Region of Turbulent Flow over Smooth and Rough Boundaries (A. Grass and M. M...
Justina X. Caushi, Jiajia Zhang, Zhicheng Ji, Ajay Vaghasia et al.
Abstract PD-1 blockade unleashes CD8 T cells 1 , including those specific for mutation-associated neoantigens (MANA), but factors in the tumour microenvironment can inhibit these T cell responses. Single-cell transcriptomics have revealed global T cell dysfunction programs in tumour-infiltrating lym...
Güven Eken, Leon Bennun, Thomas M. Brooks, Will Darwall et al.
Site conservation is among the most effective means to reduce global biodiversity loss. Therefore, it is critical to identify those sites where unique biodiversity must be conserved immediately. To this end, the concept of key biodiversity areas (KBAs) has been developed, seeking to identify and, ul...
Monika Karmin, Lauri Saag, Mário Vicente, Melissa A. Wilson Sayres et al.
It is commonly thought that human genetic diversity in non-African populations was shaped primarily by an out-of-Africa dispersal 50-100 thousand yr ago (kya). Here, we present a study of 456 geographically diverse high-coverage Y chromosome sequences, including 299 newly reported samples. Applying ...
Alan MacDonald, H.C. Bonsor, Kazi Matin Ahmed, W. G. Burgess et al.
Luca Pagani, Daniel J. Lawson, Evelyn Jagoda, Alexander Mörseburg et al.
High-coverage whole-genome sequence studies have so far focused on a limited number of geographically restricted populations, or been targeted at specific diseases, such as cancer. Nevertheless, the availability of high-resolution genomic data has led to the development of new methodologies for infe...
Serge M. Garcia, Jeppe Kolding, J. Rice, M.-J. Rochet et al.
Balanced fishing across a range of species, stocks, and sizes could mitigate adverse effects and address food security better than increased selectivity.
Sarah K. Wise, Cecelia Damask, Lauren T. Roland, Charles S. Ebert et al.
BACKGROUND: In the 5 years that have passed since the publication of the 2018 International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR-Allergic Rhinitis 2018), the literature has expanded substantially. The ICAR-Allergic Rhinitis 2023 update presents 144 individual topics ...