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Results for “"B Botting"”

8 results

Exome-wide association study of plasma lipids in >300,000 individuals

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Charge Diabetes Working Group, Dajiang J. Liu, VA Million Veteran Program, Gina M. Peloso et al.

Journal: Nature GeneticsYear: 2017Citations: 595

We screened variants on an exome-focused genotyping array in >300,000 participants (replication in >280,000 participants) and identified 444 independent variants in 250 loci significantly associated with total cholesterol (TC), high-density-lipoprotein cholesterol (HDL-C), low-density-lipoprotein ch...

Health SciencesMedicineCardiology and Cardiovascular MedicineOpen Access
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Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease

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Wei Zhao, Asif Rasheed, Emmi Tikkanen, Jung‐Jin Lee et al.

Journal: Nature GeneticsYear: 2017Citations: 296

To evaluate the shared genetic etiology of type 2 diabetes (T2D) and coronary heart disease (CHD), we conducted a genome-wide, multi-ancestry study of genetic variation for both diseases in up to 265,678 subjects for T2D and 260,365 subjects for CHD. We identify 16 previously unreported loci for T2D...

Life SciencesBiochemistry, Genetics and Molecular BiologyGeneticsOpen Access
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Sudden infant death syndrome and postneonatal mortality in immigrants in England and Wales.

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R Balarajan, Veena Raleigh, B Botting

Journal: BMJYear: 1989Citations: 115

To examine ethnic differences in postneonatal mortality and the incidence of sudden infant death in England and Wales during 1982-5 records were analysed, the mother's country of birth being used to determine ethnic group. Postneonatal mortality was highest in infants of mothers born in Pakistan (6....

Health SciencesHealth ProfessionsGeneral Health ProfessionsOpen Access
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Mortality from congenital malformations in England and Wales: variations by mother's country of birth.

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R Balarajan, Veena Raleigh, B Botting

Journal: Archives of Disease in ChildhoodYear: 1989Citations: 31

Stillbirth and infant mortality from congenital malformations in England and Wales during 1981-5 was investigated according to the mother's country of birth. Significant differences remained after standardising for maternal age and social class. The highest overall mortality was in infants of mother...

Health SciencesMedicinePediatrics, Perinatology and Child HealthOpen Access
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Effect of Deficit Irrigation on Raised Bed Wheat Cultivation

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R. Zaman, Abdur Akanda, S. K. Biswas, MR Islam

Journal: Cercetari Agronomice in MoldovaYear: 2017Citations: 11

Abstract The experiment was conducted during Rabi season of 2015-2016 and 2016-2017 at the Regional Agricultural Research station, BARI, Ishurdi, Pabna, Bangladesh, to determine the water requirements of wheat on raised bed and the effect of different deficit irrigation on yield, water use efficienc...

Life SciencesAgricultural and Biological SciencesSoil ScienceOpen Access
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Multi-ancestry polygenic risk scores for the prediction of type 2 diabetes and complications in diverse ancestries

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Alicia Huerta‐Chagoya, Joohyun Kim, Ravi Mandla, Yingchang Lu et al.

Journal: The Lancet Diabetes & EndocrinologyYear: 2025Citations: 2

BACKGROUND: Polygenic risk scores (PRSs) improve prediction of the development of type 2 diabetes over the use of clinical risk factors alone; however, they perform poorly in populations of non-European ancestry, limiting their global clinical utility. We aimed to deliver comprehensive and rigorousl...

Life SciencesBiochemistry, Genetics and Molecular BiologyGeneticsOpen Access
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Anxiety in adults with asthma during the coronavirus disease 2019 pandemic: a Canadian perspective

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Sophia Linton, Kayley Xu, Lubnaa Hossenbaccus, Hannah Botting et al.

Journal: Research SquareYear: 2023

Background Asthma is a chronic airway inflammatory disease that affects millions of Canadians and often contributes to higher levels of anxiety among patients. Since the coronavirus disease 2019 (COVID-19) pandemic was a time of increased anxiety among the Canadian population, it was thought that th...

Social SciencesPsychologyClinical PsychologyOpen Access
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Potential usage of Zerumbone to suppress inflammation: An in silico study

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Muhammed Amanat, A F M Shahid Ud Daula, Fakhrul Islam

Journal: Zenodo (CERN European Organization for Nuclear Research)Year: 2022

<strong>ABSTRACT</strong> A significant cyclic sesquiterpenoid known as Zerumbone was extracted from <em>Zingiber roseum</em> using the volume liquid chromatographic (VLC) technique. It’s a naturally occurring phytochemical having a variety of physiological properties, including antioxidant, anti-ul...

Life SciencesPharmacology, Toxicology and PharmaceuticsPharmacologyOpen Access
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