Daniel J. Klionsky, Amal Kamal Abdel‐Aziz, Sara Abdelfatah, Mahmoud Abdellatif et al.
autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field.
Giovanni Battista Migliori, Simon Tiberi, Alimuddin Zumla, Eskild Petersen et al.
The continuous flow of new research articles on MDR-TB diagnosis, treatment, prevention and rehabilitation requires frequent update of existing guidelines. This review is aimed at providing clinicians and public health staff with an updated and easy-to-consult document arising from consensus of Glob...
Borisov Se, Edvardas Danila, Andrei Maryandyshev, Margareth Pretti Dalcolmo et al.
The World Health Organization (WHO) recommends that countries implement pharmacovigilance and collect information on active drug safety monitoring (aDSM) and management of adverse events. The aim of this prospective study was to evaluate the frequency and severity of adverse events to anti-tuberculo...
Mohammad Javad Nasiri, Moein Zangiabadian, Erfan Arabpour, S. Amini et al.
INTRODUCTION: Multidrug-resistant tuberculosis (MDR-TB) is a life-threatening condition needing long poly-chemotherapy regimens. As no systematic reviews/meta-analysis is available to comprehensively evaluate the role of delamanid (DLM), we evaluated its effectiveness and safety. METHODS: We reviewe...
Sajib Chakraborty, Ambrosius P. Snijders, Rajib Chakravorty, Musaddeque Ahmed et al.
CRISPRs are a diverse family of DNA repeat sequences that are widely distributed among archaea and bacteria. The CRISPR locus is usually composed of three key elements; direct repeats (DRs), spacer sequences and the cas genes. Although recent studies have suggested that spacers may be of extrachromo...
Onno W. Akkerman, Alena Aleksa, Jan‐Willem C. Alffenaar, Nada Hassan Al-Marzouqi et al.
The World Health Organization launched a global initiative, known as aDSM (active TB drug safety monitoring and management) to better describe the safety profile of new treatment regimens for drug-resistant tuberculosis (TB) in real-world settings. However, comprehensive surveillance is difficult to...
Francine Forrest, Euan D. Reavie, John P. Smol
Paleolimnological analysis of microfossils and physical sediment characteristics in 210Pb and Ambrosia dated sediment cores, along with diatom-inferred total phosphorus concentration [TP] reconstructions, were used to determine the trophic histories (ca 200 years) of four lakes within the Rideau Can...
Giovanni Sotgiu, Simon Tiberi, Rosella Centis, Lia D’Ambrosio et al.
In spite of the recent introduction of two new drugs (delamanid and bedaquiline) and a few repurposed compounds to treat multidrug-resistant and extensively drug-resistant tuberculosis (MDR- and XDR-TB), clinicians are facing increasing problems in designing effective regimens in severe cases. Recen...
S Koirala, Borisov Se, Edvardas Danila, Andrei Mariandyshev et al.
The World Health Organization (WHO) recommends countries introduce new anti-TB drugs in the treatment of multidrug-resistant tuberculosis. The aim of the study is to prospectively evaluate the effectiveness of bedaquiline (and/or delamanid)- containing regimens in a large cohort of consecutive TB pa...
Viviane Paquin, Lonnie W. Aarssen
Evidence is reported for size-dependent (allometric) gender allocation in the monoecious, wind-pollinated annual Ambrosia artemissifolia. Consistent with established theory, the pattern of allometry displayed adaptive plasticity, depending on the environmental cause of variation in plant size. Plant...
Francesco Della Puppa, Maurizio Ambrosini
Abstract In this article – based on 100 in‐depth interviews with divided and reunited Bangladeshi families in Italy, Bangladesh, and London – we discuss how remittances are influenced by gender relations within the family, what social meanings they assume, what family memberships they reinforce, how...
Giovanni Battista Migliori, Pei Min Thong, Jan‐Willem C. Alffenaar, Justin T. Denholm et al.
The objective of this study was to describe country-specific lockdown measures and tuberculosis indicators collected during the first year of the COVID-19 pandemic. Data on lockdown/social restrictions (compulsory face masks and hand hygiene; international and local travel restrictions; restrictions...
Simona Baránková, Joan Pere Pascual‐Díaz, Nusrat Sultana, M. Pilar Alonso‐Lifante et al.
This work has been supported by the Dirección General de Investigación Científica y Técnica (Spanish Government: CGL2016-75694-P AEI/FEDER, UE; CGL2017-84297-R), by the Generalitat de Catalunya (‘Ajuts a grups de recerca consolidats’ 2017SGR01116’), by the Czech Science Foundation (grants 16-08698S,...
Emanuele Pontali, Dina Visca, Rosella Centis, Lia D’Ambrosio et al.
PURPOSE OF REVIEW: Multidrug-resistant (MDR) tuberculosis (TB) and extensively drug-resistant (XDR)-TB epidemics are key obstacles towards TB control and elimination. RECENT FINDINGS: Diagnosis of MDR/XDR-TB is difficult and requires several weeks. New diagnostic tools are being tested and proposed ...
Vincenzo Nasca, Francesco Barretta, Francesca Corti, Sara Lonardi et al.
BACKGROUND: Immune checkpoint inhibitors (ICIs) show a tremendous activity in microsatellite instability-high (MSI-H) metastatic colorectal cancer (mCRC), but a consistent fraction of patients does not respond. Prognostic/predictive markers are needed. Despite previous investigations in other tumor ...
Koffi Koba, Catherine Guyon, C. Raynaud, Jean-Pierre Chaumont et al.
The leaf essential oil of Chromolaena odorata L. (Chenopodiaceae) from Togo were steam-distilled, analyzed by GC and GC-MS for chemical composition and investigated in vitro for its potential cytotoxic activity on human epidermic cell line HaCat. The chemical composition showed that the main constit...
Marcela Muñóz-Torrico, J.A. Caminero Luna, Giovanni Battista Migliori, Lia D’Ambrosio et al.
Diabetes mellitus (DM) is a well-known risk factor for tuberculosis (TB). However, it is not known to what extent DM affects the outcome in patients with multidrug-resistant (MDR-TB) and extensively drug-resistant TB (XDR-TB) treated with second-line anti-TB drugs. The objective of this study was to...
M. Aguilar, B. Alpat, G. Ambrosi, H. R. Anderson et al.
Precision measurements by the Alpha Magnetic Spectrometer (AMS) on the International Space Station of the deuteron (D) flux are presented. The measurements are based on 21×10^{6} D nuclei in the rigidity range from 1.9 to 21 GV collected from May 2011 to April 2021. We observe that over the entire r...
M. Aguilar, G. Ambrosi, H. R. Anderson, L. Arruda et al.
We present results over an 11-year Solar cycle of cosmic antiprotons based on 1.1×10^{6} events in the rigidity range from 1.00 to 41.9 GV. The p[over ¯] fluxes exhibit distinct properties. The magnitude of the p[over ¯] flux temporal variation is significantly smaller than those of p, e^{-}, and e^...
Ji Hyeon Son, Md Atikul Islam, Joon Ho Hong, Ji Young Jeong et al.
Abstract This study was designed to analyze the volatile organic compounds in the leaves of Ambrosia artemisiifolia L. and Artemisia annua L. from Korea. For extraction of volatile compounds, headspace-solid phase micro extraction (HS-SPME) and simultaneous distillation extraction (SDE) were applied...