Lorenzo de la Rica, Javier Rodríguez‐Ubreva, Mireia García, Abul Bashar Mir Md. Khademul Islam et al.
BACKGROUND: DNA methylation is a key epigenetic mechanism for driving and stabilizing cell-fate decisions. Local deposition and removal of DNA methylation are tightly coupled with transcription factor binding, although the relationship varies with the specific differentiation process. Conversion of ...
Lorenzo de la Rica, José Urquiza, David Gómez-Cabrero, Abul Bashar Mir Md. Khademul Islam et al.
Autoimmune rheumatic diseases are complex disorders, whose etiopathology is attributed to a crosstalk between genetic predisposition and environmental factors. Both variants of autoimmune susceptibility genes and environment are involved in the generation of aberrant epigenetic profiles in a cell-sp...
Rajeev K. Singla, Ronita De, Thomas Efferth, Bruno Mezzetti et al.
BACKGROUND: The development of digital technologies and the evolution of open innovation approaches have enabled the creation of diverse virtual organizations and enterprises coordinating their activities primarily online. The open innovation platform titled "International Natural Product Sciences T...
Roser Vento‐Tormo, Javier Rodríguez‐Ubreva, Lorena Di Lisio, Abul Bashar Mir Md. Khademul Islam et al.
MicroRNAs (miRNAs) have negative effects on gene expression and are major players in cell function in normal and pathological conditions. Epstein-Barr virus (EBV) infection of resting B lymphocytes results in their growth transformation and associates with different B cell lymphomas. EBV-mediated B ...
Maria Kletečka-Pulker, Himel Mondal, Dongdong Wang, R. Gonzalo Parra et al.
The open innovation hub Digital Health and Patient Safety Platform (DHPSP) was recently established with the purpose to invigorate collaborative scientific research and the development of new digital products and personalized solutions aiming to improve human health and patient safety. In this study...