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Results for “"Lei Zhang"”

21+ results

Space-time-coding digital metasurfaces

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Lei Zhang, Xiao Qing Chen, Shuo Liu, Qian Zhang et al.

Journal: Nature CommunicationsYear: 2018Citations: 1207

The recently proposed digital coding metasurfaces make it possible to control electromagnetic (EM) waves in real time, and allow the implementation of many different functionalities in a programmable way. However, current configurations are only space-encoded, and do not exploit the temporal dimensi...

Physical SciencesMaterials ScienceElectronic, Optical and Magnetic MaterialsOpen Access
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Marine Sponge Derived Natural Products between 2001 and 2010: Trends and Opportunities for Discovery of Bioactives

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Mohammad F. Mehbub, Jie Lei, Christopher M. M. Franco, Wei Zhang

Journal: Marine DrugsYear: 2014Citations: 409

Marine sponges belonging to the phylum Porifera (Metazoa), evolutionarily the oldest animals are the single best source of marine natural products. The present review presents a comprehensive overview of the source, taxonomy, country of origin or geographical position, chemical class, and biological...

Life SciencesBiochemistry, Genetics and Molecular BiologyBiotechnologyOpen Access
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Shifting machine learning for healthcare from development to deployment and from models to data

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Angela Zhang, Lei Xing, James Zou, Joseph C. Wu

Journal: Nature Biomedical EngineeringYear: 2022Citations: 392

In the past decade, the application of machine learning (ML) to healthcare has helped drive the automation of physician tasks as well as enhancements in clinical capabilities and access to care. This progress has emphasized that, from model development to model deployment, data play central roles. I...

Physical SciencesComputer ScienceArtificial IntelligenceOpen Access
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Information Metamaterial Systems

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Tie Jun Cui, Lianlin Li, Shuo Liu, Qian Ma et al.

Journal: iScienceYear: 2020Citations: 233

Metamaterials have great capabilities and flexibilities in controlling electromagnetic (EM) waves because their subwavelength meta-atoms can be designed and tailored in desired ways. However, once the structure-only metamaterials (i.e., passive metamaterials) are fabricated, their functions will be ...

Physical SciencesMaterials ScienceElectronic, Optical and Magnetic MaterialsOpen Access
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Deficient Chaperone-Mediated Autophagy Promotes Inflammation and Atherosclerosis

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Lei Qiao, Jing Ma, Zihao Zhang, Wenhai Sui et al.

Journal: Circulation ResearchYear: 2021Citations: 176

Rationale: The NLRP3 (NLR [NOD-like receptor] family, pyrin domain containing 3) inflammasome is an important driver of atherosclerosis. Our previous study shows that chaperone-mediated autophagy (CMA), one of the main lysosomal degradative process, has a regulatory role in lipid metabolism of macro...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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MMP-2 and 9 in Chronic Kidney Disease

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Zhengyuan Cheng, Manoj Hang Limbu, Zhi Wang, Jing Liu et al.

Journal: International Journal of Molecular SciencesYear: 2017Citations: 155

Gelatinases are members of the matrix metalloproteinase (MMPs) family; they play an important role in the degradation of the extracellular matrix (ECM). This effect is also crucial in the development and progression of chronic kidney disease (CKD). Its expression, as well as its activity regulation ...

Life SciencesBiochemistry, Genetics and Molecular BiologyCancer ResearchOpen Access
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Gasdermin D-dependent platelet pyroptosis exacerbates NET formation and inflammation in severe sepsis

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Meiling Su, Chaofei Chen, Shaoying Li, Musheng Li et al.

Journal: Nature Cardiovascular ResearchYear: 2022Citations: 152

Platelets have emerged as key inflammatory cells implicated in the pathology of sepsis, but their contributions to rapid clinical deterioration and dysregulated inflammation have not been defined. Here, we show that the incidence of thrombocytopathy and inflammatory cytokine release was significantl...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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3D Metaphotonic Nanostructures with Intrinsic Chirality

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Meng Qiu, Lei Zhang, Zhixiang Tang, Wei Jin et al.

Journal: Advanced Functional MaterialsYear: 2018Citations: 142

Abstract Chirality is a universal geometric property in both micro‐ and macroworlds. Recently, optical chiral effects have drawn increased attention due to their great potential in fundamental studies and practical applications. Significantly, the optical chiral response of artificial structures can...

Physical SciencesMaterials ScienceElectronic, Optical and Magnetic MaterialsOpen Access
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Pseudohalide‐Induced Recrystallization Engineering for CH<sub>3</sub>NH<sub>3</sub>PbI<sub>3</sub> Film and Its Application in Highly Efficient Inverted Planar Heterojunction Perovskite Solar Cells

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Hua Dong, Zhaoxin Wu, Jun Xi, Xiaobao Xu et al.

Journal: Advanced Functional MaterialsYear: 2017Citations: 136

Abstract High crystallinity and compactness of the active layer is essential for metal‐halide perovskite solar cells. Here, a simple pseudohalide‐induced film retreatment technology is developed as the passivation for preformed perovskite film. It is found that the retreatment process yields a contr...

Physical SciencesEngineeringElectrical and Electronic Engineering
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Stable and efficient pure blue quantum-dot LEDs enabled by inserting an anti-oxidation layer

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Wenjing Zhang, Bo Li, Chun Chang, Fei Chen et al.

Journal: Nature CommunicationsYear: 2024Citations: 135

Abstract The efficiency and stability of red and green quantum-dot light-emitting diodes have already met the requirements for commercialization in displays. However, the poor stability of the blue ones, particularly pure blue color, is hindering the commercialization of full-color quantum-dot light...

Physical SciencesMaterials ScienceMaterials ChemistryOpen Access
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Heterovalent-doping-enabled atom-displacement fluctuation leads to ultrahigh energy-storage density in AgNbO3-based multilayer capacitors

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Lifeng Zhu, Shiqing Deng, Lei Zhao, Gen Li et al.

Journal: Nature CommunicationsYear: 2023Citations: 124

Abstract Dielectric capacitors with high energy storage performance are highly desired for next-generation advanced high/pulsed power capacitors that demand miniaturization and integration. However, the poor energy-storage density that results from the low breakdown strength, has been the major chal...

Physical SciencesMaterials ScienceMaterials ChemistryOpen Access
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Conjugated Molecules “Bridge”: Functional Ligand toward Highly Efficient and Long‐Term Stable Perovskite Solar Cell

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Hua Dong, Jun Xi, Lijian Zuo, Jingrui Li et al.

Journal: Advanced Functional MaterialsYear: 2019Citations: 123

Abstract Interfacial ligand passivation engineering has recently been recognized as a promising avenue, contributing simultaneously to the optoelectronic characteristics and moisture/operation tolerance of perovskite solar cells. To further achieve a win‐win situation of both performance and stabili...

Physical SciencesEngineeringElectrical and Electronic EngineeringOpen Access
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Sodium‐Ion and Polyaniline Co‐Intercalation into Ammonium Vanadate Nanoarrays Induced Enlarged Interlayer Spacing as High‐Capacity and Stable Cathodes for Flexible Aqueous Zinc‐Ion Batteries

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Song Zhao, Shuai Wang, Jiabin Guo, Lei Li et al.

Journal: Advanced Functional MaterialsYear: 2023Citations: 115

Abstract Vanadate oxides with low price and high theoretical capacity are competitive cathodes for aqueous zinc‐ion batteries (AZIBs). However, the existing problems such as sluggish Zn 2+ ion mobility, weak conductivity, and complicated flexible electrode preparation hinder the development of their...

Physical SciencesEngineeringElectrical and Electronic Engineering
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Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations

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Wiebke Albrecht, Franziska Kappenberg, Tim Brecklinghaus, Regina Stoeber et al.

Journal: Archives of ToxicologyYear: 2019Citations: 114

Drug-induced liver injury (DILI) cannot be accurately predicted by animal models. In addition, currently available in vitro methods do not allow for the estimation of hepatotoxic doses or the determination of an acceptable daily intake (ADI). To overcome this limitation, an in vitro/in silico method...

Life SciencesPharmacology, Toxicology and PharmaceuticsPharmacologyOpen Access
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Multichannel direct transmissions of near-field information

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Xiang Wan, Qian Zhang, Tian Yi Chen, Lei Zhang et al.

Journal: Light Science & ApplicationsYear: 2019Citations: 113

A digital-coding programmable metasurface (DCPM) is a type of functional system that is composed of subwavelength-scale digital coding elements with opposite phase responses. By configuring the digital coding elements, a DCPM can construct dynamic near-field image patterns in which the intensity of ...

Physical SciencesMaterials ScienceElectronic, Optical and Magnetic MaterialsOpen Access
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An Electrochromic Nickel Phosphate Film for Large-Area Smart Window with Ultra-Large Optical Modulation

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Pengyang Lei, Jinhui Wang, Yi Gao, Chengyu Hu et al.

Journal: Nano-Micro LettersYear: 2023Citations: 111

Abstract Exploring materials with high electrochemical activity is of keen interest for electrochemistry-controlled optical and energy storage devices. However, it remains a great challenge for transition metal oxides to meet this feature due to their low electron conductivity and insufficient react...

Physical SciencesMaterials SciencePolymers and PlasticsOpen Access
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4D printing roadmap

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Mahdi Bodaghi, Linlin Wang, Fenghua Zhang, Yanju Liu et al.

Journal: Smart Materials and StructuresYear: 2024Citations: 107

Abstract Four-dimensional (4D) printing is an advanced manufacturing technology that has rapidly emerged as a transformative tool with the capacity to reshape various research domains and industries. Distinguished by its integration of time as a dimension, 4D printing allows objects to dynamically r...

Physical SciencesEngineeringAutomotive EngineeringOpen Access
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Genome‐wide analysis of somatic copy number alterations and chromosomal breakages in osteosarcoma

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Jan Smida, Hongen Xu, Yanping Zhang, Daniel Baumhoer et al.

Journal: International Journal of CancerYear: 2017Citations: 102

Osteosarcoma (OS) is the most common primary malignant bone tumor in children and adolescents. It is characterized by highly complex karyotypes with structural and numerical chromosomal alterations. The observed OS-specific characteristics in localization and frequencies of chromosomal breakages str...

Life SciencesBiochemistry, Genetics and Molecular BiologyCancer Research
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Emerging Amorphous to Crystalline Conversion Chemistry in Ca‐Doped VO<sub>2</sub> Cathodes for High‐Capacity and Long‐Term Wearable Aqueous Zinc‐Ion Batteries

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Jiabin Guo, Bing He, Wenbin Gong, Shuhong Xu et al.

Journal: Advanced MaterialsYear: 2023Citations: 100

Abstract Amorphous transition metal oxides have attracted significant attention in energy storage devices owing to their potentially desirable electrochemical properties caused by abundant unsaturated dangling bonds. However, the amorphization further amplifies the shortcoming of the poor intrinsic ...

Physical SciencesEngineeringElectrical and Electronic Engineering
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TGFB1 induces fetal reprogramming and enhances intestinal regeneration

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Lei Chen, Xia Qiu, Abigail Dupre, Oscar Pellón-Cárdenas et al.

Journal: Cell stem cellYear: 2023Citations: 96

The gut epithelium has a remarkable ability to recover from damage. We employed a combination of high throughput sequencing approaches, mouse genetics, and murine and human organoids, and identified a role for TGFB signaling during intestinal regeneration following injury. At 2 days following irradi...

Life SciencesBiochemistry, Genetics and Molecular BiologyGeneticsOpen Access
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