Ali A. Rabaan, Shamsah H. Al-Ahmed, Javed Muhammad, Amjad Khan et al.
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a severe pandemic of the current century. The vicious tentacles of the disease have been disseminated worldwide with unknown complications and repercussions. Advanced COVID-19 syndrome is ...
T. K. Goswami, Mithilesh Singh, Manish Dhawan, Saikat Mitra et al.
Autoimmune diseases are caused when immune cells act against self-protein. This biological self-non-self-discrimination phenomenon is controlled by a distinct group of lymphocytes known as regulatory T cells (Tregs), which are key inflammatory response regulators and play a pivotal role in immune to...
Ali A. Rabaan, Raghavendra Tirupathi, Anupam Sule, Jehad Aldali et al.
Real-time RT-PCR is considered the gold standard confirmatory test for coronavirus disease 2019 (COVID-19). However, many scientists disagree, and it is essential to understand that several factors and variables can cause a false-negative test. In this context, cycle threshold (Ct) values are being ...
Kuldeep Dhama, Shailesh Kumar Patel, Rakesh Kumar, Rupali Masand et al.
Disinfectants and sanitizers are essential preventive agents against the coronavirus disease 2019 (COVID-19) pandemic; however, the pandemic crisis was marred by undue hype, which led to the indiscriminate use of disinfectants and sanitizers. Despite demonstrating a beneficial role in the control an...
Mina Ziarati, Mohammad Jalil Zorriehzahra, Fatemeh Hassantabar, Zibandeh Mehrabi et al.
spp. are also considered fish-derived zoonotic pathogens. Two groups of fish-associated fungi causing basidiobolomycosis and sporotrichosis also pose a zoonotic risk for humans. The majority of the fish-derived zoonotic diseases are transmitted to humans mainly via the consumption of improperly cook...
Kuldeep Dhama, Khan Sharun, Ruchı Tıwarı, Manish Dhawan et al.
The ongoing coronavirus disease (COVID-19) vaccination drive aims to achieve global vaccination coverage that will help to control the pandemic. Therefore, the individuals who are reluctant to be vaccinated or forego COVID-19 vaccination can delay the progress of overall vaccination coverage, leadin...
Izabela Michalak, Ruchi Tiwari, Manish Dhawan, Mahmoud Alagawany et al.
Natural antioxidants applied as feed additives can improve not only animals' health and overall performance but also increase their resistance to environmental stress such as heat stress, bad housing conditions, diseases, etc. Marine organisms, for example seaweeds - red, brown, and green macroalgae...
Kuldeep Dhama, Manish Dhawan, Ruchi Tiwari, Talha Bin Emran et al.
Multiple vaccines have recently been developed, and almost all the countries are presently vaccinating their population to tackle the COVID-19 pandemic. Most of the COVID-19 vaccines in use are administered via intramuscular (IM) injection, eliciting protective humor and cellular immunity. COVID-19 ...
Abu Montakim Tareq, Talha Bin Emran, Kuldeep Dhama, Manish Dhawan et al.
We are sharing the results of our study which retrospectively looked at the impact of SARS-CoV-2 delta variant amid coronavirus disease 2019 (COVID-19) ongoing pandemic.Severe acute respiratory syn...
Ali A. Rabaan, Shamsah H. Al-Ahmed, Mohammed Garout, Ayman M. Al‐Qaaneh et al.
The pathogenesis of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is still not fully unraveled. Though preventive vaccines and treatment methods are out on the market, a specific cure for the disease has not been discovered. Recent inves...
Rakesh Kumar, Cut Meurah Yeni, Niken Asri Utami, Rupali Masand et al.
The ongoing coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a global public health problem. The SARS-CoV-2 triggers hyper-activation of inflammatory and immune responses resulting in cytokine storm and increased inflammatory re...
Fahadul Islam, Manish Dhawan, Mohamed H. Nafady, Talha Bin Emran et al.
Despite many nations' best efforts to contain the so-called COVID-19 pandemic, the emergence of the SARS-CoV-2 Omicron strain (B.1.1.529) has been identified as a serious concern. After more than two years of COVID-19 pandemic and more than a year of worldwide vaccination efforts, the globe will not...
Jigarji Chaturji Thakor, M. Dinesh, Rajendran Manikandan, Suresh Bindu et al.
Swine coronaviruses (SCoVs) are one of the most devastating pathogens affecting the livelihoods of farmers and swine industry across the world. These include transmissible gastroenteritis virus (TGEV), porcine epidemic diarrhea virus (PEDV), porcine respiratory coronavirus (PRCV), porcine hemaggluti...
Manish Dhawan, Ali A. Rabaan, Mahmoud M. Al Fawarah, Souad A. Almuthree et al.
The emergence of novel variants of SARS-CoV-2 and their abilities to evade the immune response elicited through presently available vaccination makes it essential to recognize the mechanisms through which SARS-CoV-2 interacts with the human immune response. It is essential not only to comprehend the...
Ishani Chakrabartty, Maryam Khan, Saurov Mahanta, Hitesh Chopra et al.
From many decades, emerging infections have threatened humanity. The pandemics caused by different CoVs have already claimed and will continue to claim millions of lives. The SARS, Ebola, MERS epidemics and the most recent emergence of COVID-19 pandemic have threatened populations across borders. Si...
Fahadul Islam, Maniza Muni, Saikat Mitra, Talha Bin Emran et al.
A group of bioactive, isoprenoid pigments known as carotenoids is mostly present in fruits and vegetables. Carotenoids are essential for the prevention of physiological issues, which makes maintaining excellent health easier. They are effective functional ingredients with potent health-promoting pro...
Manish Dhawan, Talha Bin Emran, Priyanaka, Om Prakash Choudhary
The COVID-19 pandemic has led to severe financial, clinical, and societal repercussions and imposed more pressure on the healthcare system of many nations. COVID-19 impacts the immune system by causing a systemic inflammatory reaction, often known as cytokine release syndrome (CRS). COVID-19 patient...
Suresh Bindu, Satyabrata Dandapat, Rajendran Manikandan, M. Dinesh et al.
Trained immunity is a renewed concept of innate immune memory that facilitates the innate immune system to have the capacity to remember and train cells via metabolic and transcriptional events to enable them to provide nonspecific defense against the subsequent encounters with a range of pathogens ...
Manish Dhawan, AbdulRahman A. Saied, Talha Bin Emran, Om Prakash Choudhary
Manish Dhawan, AbdulRahman A. Saied, Talha Bin Emran and Om Prakash Choudhary 1) Department of Microbiology, Punjab Agricultural University, Ludhiana 141004, India, 2) Trafford College, Altrincham, Manchester WA14 5PQ, UK, 3) National Food Safety Authority (NFSA), Aswan Branch, Aswan 81511, Egypt, 4...
Geetika Verma, Manish Dhawan, AbdulRahman A. Saied, Geetika Kaur et al.
INTRODUCTION: The novel coronavirus infectious disease 2019 (COVID-19) which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has emerged as a gigantic problem. The lung is the major target organ of SARS-CoV-2 and some of its variants like Delta and Omicron variant adapted i...