Md. Korban Ali, Rahman Md Moshikur, Rie Wakabayashi, Yoshiro Tahara et al.
Ionic liquid (IL) surfactants have attracted great interest as promising substitutes for conventional surfactants owing to their exceptional and favorable physico-chemical properties. However, most IL surfactants are not eco-friendly and form unstable micelles, even when using a high concentration o...
Rafiqul Islam, Shihab Uddin, Md. Raihan Chowdhury, Rie Wakabayashi et al.
Since injection administration for diabetes is invasive, it is important to develop an effective transdermal method for insulin. However, transdermal delivery remains challenging owing to the strong barrier function of the stratum corneum (SC) of the skin. Here, we developed ionic liquid (IL)-in-oil...
Rafiqul Islam, Md. Raihan Chowdhury, Rie Wakabayashi, Yoshiro Tahara et al.
Transdermal delivery of drugs is more challenging for drugs that are insoluble or sparingly soluble in water and most organic solvents. To overcome this problem, ionic liquid (IL)-mediated ternary systems have been suggested as potential drug carriers. Here, we report potent ternary (IL-EtOH-IPM) sy...
Rafiqul Islam, Md. Raihan Chowdhury, Rie Wakabayashi, Noriho Kamiya et al.
The transdermal delivery of sparingly soluble drugs is challenging due to of the need for a drug carrier. In the past few decades, ionic liquid (IL)-in-oil microemulsions (IL/O MEs) have been developed as potential carriers. By focusing on biocompatibility, we report on an IL/O ME that is designed t...
Shihab Uddin, Rafiqul Islam, Md. Raihan Chowdhury, Rie Wakabayashi et al.
Lipid-based biocompatible ionic liquids (LBILs) have attracted attention as carriers in transdermal drug delivery systems (TDDSs) because of their lipophilic character. In this study, we report the formulation of a peptide–LBIL complex microencapsulated in an oil phase as a potential carrier for the...
Shihab Uddin, Rafiqul Islam, Rahman Md Moshikur, Rie Wakabayashi et al.
Transdermal drug delivery systems (TDDSs) may be useful for preventing various diseases including cancer. However, the stratum corneum (SC) inhibits the permeation of foreign particles into the skin. To obtain an effective TDDS, we developed a protein-containing nanocarrier (PCNC) comprising an anti...
Shihab Uddin, Rafiqul Islam, Rahman Md Moshikur, Rie Wakabayashi et al.
Transcutaneous vaccination is one of the successful, affordable, and patient-friendly advanced immunization approaches because of the presence of multiple immune-responsive cell types in the skin. However, in the absence of a preferable facilitator, the skin’s outer layer is a strong impediment to d...