Tahmina Shirin, Taufiqur Rahman Bhuiyan, Richelle C. Charles, Shaheena Amin et al.
OBJECTIVES: Studies on serological responses following coronavirus disease-2019 (COVID-19) have been published primarily in individuals who are moderately or severely symptomatic, but there are few data from individuals who are mildly symptomatic or asymptomatic. METHODS: We measured IgG, IgM, and I...
Afroza Akter, Tasnuva Ahmed, Imam Tauheed, Marjahan Akhtar et al.
BACKGROUND: COVID-19 caused by SARS-CoV-2 ranges from asymptomatic to severe disease and can cause fatal and devastating outcome in many cases. In this study, we have compared the clinical, biochemical and immunological parameters across the different disease spectrum of COVID-19 in Bangladeshi pati...
Md Mahfuzur Rahman, Ananya Ferdous Hoque, Yeasir Karim, Zannat Kawser et al.
The rapid and early detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections is key to control the current Coronavirus disease 2019 (COVID-19) pandemic. The present study was conducted to clinically evaluate a rapid diagnostic test (RDT) kit, Standard Q COVID-19 Ag Test (...
Zannat Kawser, SM Shamsuzzaman
Abstract: Introduction: Infections caused by multidrug-resistant (MDR) hypervirulent Klebsiella pneumoniae are difficult to treat and associated with high mortality rates. Hence, this study was conducted to determine the antibiotic resistance pattern along with the distribution of virulence genes am...
Taufiqur Rahman Bhuiyan, Marjahan Akhtar, Fatema Khaton, Sadia Rahman et al.
To evaluate severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-specific antibody responses after Covishield vaccination for 6 months after vaccination. SARS-CoV-2-specific antibody responses were assessed by enzyme-linked immunosorbent assay of the recombinant receptor-binding domain of SA...
Zannat Kawser, Mohabbat Hossain, Sara Suliman, Shahin Lockman et al.
Early detection of SARS-CoV-2 infection is crucial to prevent its spread. This study aimed to document test sensitivity/specificity, correlation with cycle threshold value from polymerase chain reaction (PCR), fitness-for-use in different populations and settings, and user perspectives that could in...
Omar Hamza Bin Manjur, Mokibul Hassan Afrad, Manjur Hossain Khan, Mohabbat Hossain et al.
We report the coding-complete genome sequences of 25 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sublineage B.1.1.529 Omicron strains obtained from Bangladeshi individuals in samples collected between December 2021 and January 2022. Genomic data were generated by Nanopore sequencing...
Zannat Kawser, SM Shamsuzzaman
Introduction: Klebsiella pneumoniae superbug is emerging as a serious health concern as resistance to last-resort antibiotics spreads. To bypass the therapeutic molecules used today, the development of an immunoprophylactic safe approach is of great clinical relevance. This study was conducted to de...
Tahmina Shirin, Taufiqur Rahman Bhuiyan, Richelle C. Charles, Shaheena Amin et al.
Studies on serologic responses following COVID-19 have been published primarily in individuals who are moderately or severely symptomatic, but there are few data from individuals who are only mildly symptomatic or asymptomatic. To generate such data, we used World Health Organization disease severit...
Eva Muthamia, Samuel Mungai, Mary Mungai, Gama Bandawe et al.
Abstract Background The COVID-19 pandemic has resulted in a need for rapid identification of infectious cases. Testing barriers have prohibited adequate screening for SARS COV2, resulting in significant delays in treatment provision and commencement of outbreak control measures. This study aimed to ...
Zannat Kawser, Sushmita Sridhar, Sanchita Kar, Tanbir Habib et al.
BACKGROUND: Klebsiella pneumoniae (Kpn), a WHO priority pathogen with high rates of antimicrobial resistance (AMR), has emerged as a leading cause of hospital acquired pneumonia and neonatal sepsis. OBJECTIVE: We aimed to define the clinical characteristics of a cohort of patients with Kpn infection...
Sanchita Kar, Zannat Kawser, Sushmita Sridhar, Sharmin Aktar Mukta et al.
Abstract We evaluated Klebsiella pneumoniae (Kp) gut carriage in healthy, unrelated adults and children living in separate households in Dhaka, Bangladesh. Average Kp prevalence in stool samples ranged from 61% in young children (15/25) to 81% in adults (21/26), with significantly higher abundance i...
Zannat Kawser, Mohabbat Hossain, Sara Suliman, Shahin Lockman et al.
Abstract Early detection of SARS-CoV-2 infection is crucial to prevent the spread of the virus. In this study, we evaluated the performance of a commercial rapid antigen detection test, BD Veritor, and compared this (and another rapid test, Standard Q) against a gold-standard of nasopharyngeal (NP) ...
Zannat Kawser, Saikt Rahman, Emilie Westeel, Mohammad Tanbir Habib et al.
BACKGROUND: The widespread increase in multiple variants of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) since 2020 is causing significant health concerns worldwide. While whole-genome sequencing (WGS) has played a leading role in surveillance programs, many local laboratories lack t...
Umme Kulsum, Kasrina Azad, Mubasshir Washif, Mohabbat Hossain et al.
Abstract Aims Advixa is a monoclonal antibody manufactured as a biosimilar to adalimumab (Humira, Abbvie Inc.). The key objectives of this study were to use a healthy population group to assess pharmacokinetics (PK) and safety similarity between Advixa and Humira in healthy participants and to quant...
Eva Muthamia, Samuel Mungai, Mary Mungai, Gama Bandawe et al.
<ns3:p> <ns3:bold>Background</ns3:bold> : The COVID-19 pandemic has resulted in a need for rapid identification of infectious cases. Testing barriers have prohibited adequate screening for SARS-CoV-2, resulting in significant delays in commencement of treatment and outbreak control measures. This st...
Sanchita Kar, Sharmin Aktar Mukta, Zannat Kawser, Most. Arifa Akter et al.
BACKGROUND: Community-acquired pneumonia (CAP) is a leading cause of childhood mortality, with diverse etiologies. This study aimed to generate region-specific data to inform treatment and vaccination strategies for childhood CAP. METHODS: We enrolled 226 CAP cases and 201 controls (<5 years) at Dha...
Rumana Mahtarin, Kasrina Azad, Rakib Bin Mahbub Talukder, Rynak Rahmat et al.
BACKGROUND: β-thalassemia poses a considerable public health burden in Bangladesh, where a high carrier frequency underlies widespread disease risk. It is necessary to distinguish β-thalassemia trait (βTT) and iron deficiency anemia (IDA) to ensure genetic counseling and enable effective prevention ...
Rumana Mahtarin, Kasrina Azad, Rakib Bin Mahbub Talukder, Rynak Rahmat et al.
<div> Background β-thalassemia poses a considerable public health burden in Bangladesh, where a high carrier frequency underlies widespread disease risk. It is necessary to distinguish β-thalassemia trait (βTT) and iron deficiency anemia (IDA) to ensure genetic counseling and enable effective preven...
Rumana Mahtarin, Kasrina Azad, Rakib Bin Mahbub Talukder, Rynak Rahmat et al.
Discriminant formulas applied for the evaluation of the diagnosis of β-thalassemia trait (βTT) in the Bangladeshi population.