Georg Ehret, Teresa Ferreira, Daniel I. Chasman, Anne Jackson et al.
To dissect te genetic arcitecture of blood pressure and assess effects on target organ damage, we analyzed 128,272 SNPs from targeted and genome-wide arrays in 201,529 individuals of European ancestry, and genotypes from an additional 140,886 individuals were used for validation. We identified 66 ...
Alexander A. Navarini, A. David Burden, Francesca Capon, Ulrich Mrowietz et al.
Pustular psoriasis (PP) is a group of inflammatory skin conditions characterized by infiltration of neutrophil granulocytes in the epidermis to such an extent that clinically visible sterile pustules develop. Because of clinical co-incidence, PP is currently grouped with psoriasis vulgaris (PV). How...
Kyaw Myo Tun, Mallika Imwong, Khin Maung Lwin, Aye Aye Win et al.
BACKGROUND: Emergence of artemisinin resistance in southeast Asia poses a serious threat to the global control of Plasmodium falciparum malaria. Discovery of the K13 marker has transformed approaches to the monitoring of artemisinin resistance, allowing introduction of molecular surveillance in remo...
Emily Beech, Malin Rivers, Sara Oldfield, Paul Smith
This article presents, for the first time, an overview of all known tree species by scientific name and country level distribution, and describes an online database—GlobalTreeSearch—that provides access to this information. Based on our comprehensive analysis of published data sources and expert inp...
Willian A. da Silveira, Hossein Fazelinia, Sara Brin Rosenthal, Evagelia C. Laiakis et al.
Spaceflight is known to impose changes on human physiology with unknown molecular etiologies. To reveal these causes, we used a multi-omics, systems biology analytical approach using biomedical profiles from fifty-nine astronauts and data from NASA’s GeneLab derived from hundreds of samples flown in...
Daniel P. Donnelly, Catherine M. Rawlins, Caroline J. DeHart, Luca Fornelli et al.
One gene can give rise to many functionally distinct proteoforms, each of which has a characteristic molecular mass. Top-down mass spectrometry enables the analysis of intact proteins and proteoforms. Here members of the Consortium for Top-Down Proteomics provide a decision tree that guides research...
Syed Ahsanuddin Ahmed, Motunrayo Ajisola, Kehkashan Azeem, Pauline Bakibinga et al.
INTRODUCTION: With COVID-19, there is urgency for policymakers to understand and respond to the health needs of slum communities. Lockdowns for pandemic control have health, social and economic consequences. We consider access to healthcare before and during COVID-19 with those working and living in...
Naila Kabeer
* Foreword - John Gaventa * INTRODUCTION * 1. The search for inclusive citizenship: Meanings and expressions in an interconnected world.- Naila Kabeer * CITIZENSHIP AND RIGHTS * 2. Towards an actor-oriented Perspective on human rights - Celestine Nyamu-Musembi * 3. The emergence of human rights in t...
Ingrid Boas, Carol Farbotko, Helen Adams, Harald Sterly et al.
ForewordIntroduction PART 1: CLIMATE AND CULTURE1. Human Agency, Climate Change and Culture: An Archaeological Perspective, Fekri A. Hassan, University College London2. Climate and Weather Discourse in Anthropology: From Determinism to Uncertain Futures, Nicole Peterson, Columbia University, and Ken...
Shardul Agrawala, Tomoko Ota, Ahsan Uddin Ahmed, Maarten van Aalst et al.
This document is an output from the OECD Development and Climate Change project, an activity jointly overseen by the EPOC Working Party on Global and Structural Policies (WPGSP), and the DAC Network on Environment and Development Co-operation (ENVIRONET). The overall objective of the project is to p...
Guillaume Émériaud, Yolanda M. López‐Fernández, Narayan P. Iyer, Melania M. Bembea et al.
OBJECTIVES: We sought to update our 2015 work in the Second Pediatric Acute Lung Injury Consensus Conference (PALICC-2) guidelines for the diagnosis and management of pediatric acute respiratory distress syndrome (PARDS), considering new evidence and topic areas that were not previously addressed. D...
Abul Hasnat Milton, Wayne Smith, Bayzidur Rahman, Ziaul Hasan et al.
BACKGROUND: Chronic exposure to arsenic through drinking water has the potential to cause adverse pregnancy outcomes, although the association has not been demonstrated conclusively. This cross-sectional study assessed the association between arsenic in drinking water and spontaneous abortion, still...
Warish Ahmed, Stuart L. Simpson, Paul M. Bertsch, Kyle Bibby et al.
Wastewater surveillance for pathogens using reverse transcription-polymerase chain reaction (RT-PCR) is an effective and resource-efficient tool for gathering community-level public health information, including the incidence of coronavirus disease-19 (COVID-19). Surveillance of Severe Acute Respira...
Rob W. van der Pluijm, Rupam Tripura, Richard M. Hoglund, Aung Pyae Phyo et al.
BACKGROUND: Artemisinin and partner-drug resistance in Plasmodium falciparum are major threats to malaria control and elimination. Triple artemisinin-based combination therapies (TACTs), which combine existing co-formulated ACTs with a second partner drug that is slowly eliminated, might provide eff...