Jason L. Weirather, Selma M. B. Jerônimo, Shalini Gautam, Shyam Sundar et al.
The Leishmania species cause a variety of human disease syndromes. Methods for diagnosis and species differentiation are insensitive and many require invasive sampling. Although quantitative PCR (qPCR) methods are reported for leishmania detection, no systematic method to quantify parasites and dete...
Cesar I. Bin Kingombe, Geert Huys, Mauro Tonolla, M. John Albert et al.
We found 73.1 to 96.9% similarity by aligning the cytolytic enterotoxin gene of Aeromonas hydrophila SSU (AHCYTOEN; GenBank accession no. M84709) against aerolysin genes of Aeromonas spp., suggesting the possibility of selecting common primers. Identities of 90 to 100% were found among the eight sel...
Toshio Shimada, Eiji Arakawa, Kenichiro Itoh, Tadayuki Okitsu et al.
M. John Albert, Shah M. Faruque, Abu Syed Golam Faruque, P K Neogi et al.
Diarrheal diseases are highly prevalent in Bangladesh. However, the relative contribution of diarrheagenic Escherichia coli organisms--those that are enterotoxigenic (ETEC), enteropathogenic (EPEC), enteroinvasive, enterohemorrhagic, enteroaggregative, and diffuse adherent--to diarrhea in Bangladesh...
Shafiqul Alam Sarker, Thomas Casswall, Dilip Mahalanabis, NUR H. ALAM et al.
BACKGROUND: Oral ingestion of immunoglobulins in humans has been shown to be effective as prophylaxis against enteric infections. However, its therapeutic effect in children with infectious diarrhea has hitherto not been proven. We treated children with rotavirus diarrhea with immunoglobulins extrac...
M. John Albert, Khorshed Alam, Moydul Islam, Jacqueline Montanaro et al.
Hafnia alvei, a member of the family Enterobacteriaceae, was the only species of bacteria cultured from the stool of a 9-month-old child who was admitted with a 3-day history of watery diarrhea. The isolated strain of H. alvei failed to produce heat-labile or heat-stable enterotoxins or Shiga-like t...
J. A. Johnson, C A Salles, Pinaki Panigrahi, M. John Albert et al.
Although Vibrio cholerae O139 synonym Bengal strains, from the current epidemics in India and Bangladesh, are closely related to seventh-pandemic strains, as shown by multilocus enzyme electrophoresis, Bengal strains are encapsulated and portions of the O1 antigen biosynthetic complex genes found in...
Lorenzo Alfieri, Sagy Cohen, John F. Galantowicz, Guy Schumann et al.
Every year riverine flooding affects millions of people in developing countries, due to the large population exposure in the floodplains and the lack of adequate flood protection measures. Preparedness and monitoring are effective ways to reduce flood risk. State-of-the-art technologies relying on s...
M. John Albert, Shah M. Faruque, M. Ansaruzzaman, Moydul Islam et al.
Seven strains of Hafnia alvei isolated from diarrhoeal stools of children resembled enteropathogenic Escherichia coli (EPEC) in that they produced attaching-effacing (AE) lesions in rabbit ileal loops and fluorescent actin staining in infected HEp-2 cells. In addition, a DNA probe from a chromosomal...
M. John Albert
Ralf J.P. van der Valk, Eskil Kreiner‐Møller, Marjolein N. Kooijman, Mònica Guxens et al.
Common genetic variants have been identified for adult height, but not much is known about the genetics of skeletal growth in early life. To identify common genetic variants that influence fetal skeletal growth, we meta-analyzed 22 genome-wide association studies (Stage 1; N = 28 459). We identified...
Firdausi Qadri, Christine Wennerås, M. John Albert, Jaber Hossain et al.
Vibrio cholerae O139 has recently emerged as the second etiologic agent of cholera in Asia. A study was carried out to evaluate the induction of specific immune responses to the organism in V. cholerae O139-infected patients. The immune responses to V. cholerae O139 Bengal were studied in patients b...
Ingolf Kühn, M. John Albert, M. Ansaruzzaman, N. A. Bhuiyan et al.
Aeromonas isolates from patients with diarrhea in Bangladesh (n = 69), from healthy controls (n = 11), and from surface water (n = 40) were analyzed with respect to their hybridization groups (HGs) by the aid of fatty acid methyl ester (FAME) characterization and DNA fingerprinting by AFLP, biochemi...
M. John Albert, Firdausi Qadri, Mohammad A. Wahed, Tanvir Ahmed et al.
To investigate whether micronutrient supplementation could improve the vibriocidal antibody response of children to a killed oral cholera vaccine, 2-5-year-old children were randomly assigned to receive vitamin A and zinc (AZ group), vitamin A and a placebo (A group), zinc and a placebo (Z group), o...
R. Bradley Sack, M. John Albert, Khorshed Alam, P K Neogi et al.
We undertook a controlled study of children younger than 5 years in Bangladesh to determine whether enterotoxigenic Bacteroides fragilis (ETBF) was associated with diarrhea in this population. ETBF was isolated from 22 (6.1%) of 358 patients and 5 (1.2%) of 425 controls (P = 0.0001). In children you...