Marika Berglund, Anna‐Lena Lindberg, Mahfuzar Rahman, Mohammad Yunus et al.
Background Little is known about the variation in exposure to toxic metals by age and gender and other potential modifying factors. We evaluated age and gender differences by measurements of metal/element concentrations in urine in a rural population in Matlab, Bangladesh, in three age groups: 8-12 ...
Anthony D. Okely, John J. Reilly, Mark S. Tremblay, Katharina E. Kariippanon et al.
Introduction 24-hour movement behaviours (physical activity, sedentary behaviour and sleep) during the early years are associated with health and developmental outcomes, prompting the WHO to develop Global guidelines for physical activity, sedentary behaviour and sleep for children under 5 years of ...
Susan R. McCouch, Zahra-Katy Navabi, Michael Abberton, Noelle L. Anglin et al.
Over the past 70 years, the world has witnessed extraordinary growth in crop productivity, enabled by a suite of technological advances, including higher yielding crop varieties, improved farm management, synthetic agrochemicals, and agricultural mechanization. While this “Green Revolution” intensif...
Rahul Rawat, Phuong Hong Nguyen, Disha Ali, Kuntal Kumar Saha et al.
BACKGROUND: Traditionally, impact evaluations have focused primarily on answering what impact programs or interventions have, with less attention to how or why impacts are achieved, or not achieved. The Alive & Thrive initiative, a 6-year program that aims to improve infant and young child feeding (...
Amol C. Shetty, Christopher G. Jacob, Fang Huang, Yao Li et al.
Estimates of Plasmodium falciparum migration may inform strategies for malaria elimination. Here we elucidate fine-scale parasite population structure and infer recent migration across Southeast Asia using identity-by-descent (IBD) approaches based on genome-wide single nucleotide polymorphisms call...
Phuong Hong Nguyen, Lieven Huybregts, Tina G. Sanghvi, Lan Mai Tran et al.
Background: The Minimum Dietary Diversity for Women (MDD-W) indicator based on a 10-food group women dietary diversity score (WDDS-10) has been validated to assess dietary quality in nonpregnant women. Little is known about its applicability in pregnant women, and specifically pregnant adolescent gi...
Derek Headey, Phuong Hong Nguyen, Sunny S. Kim, Rahul Rawat et al.
It has recently been hypothesized that exposure to livestock constitutes a significant risk factor for diarrhea and environmental enteric disorder in young children, which may significantly contribute to undernutrition. To date, though, very little research has documented the extent of exposure to a...
Elisabeth Njamkepo, Nizar Fawal, Alicia Tran-Dien, Jane Hawkey et al.
Together with plague, smallpox and typhus, epidemics of dysentery have been a major scourge of human populations for centuries1. A previous genomic study concluded that Shigella dysenteriae type 1 (Sd1), the epidemic dysentery bacillus, emerged and spread worldwide after the First World War, with no...
Kim E. Kortekaas, Nienke Solleveld‐Westerink, Basile Tessier‐Cloutier, Tessa Rutten et al.
AIMS: The most commonly mutated gene in vulvar squamous cell carcinoma (VSCC) is TP53 and its prognostic value, particularly in HPV-independent VSCC, is uncertain. In other tumours, p53 immunohistochemistry (IHC) is an excellent surrogate marker for TP53 mutations. In order to study this in VSCC, we...
Li Zhang, Isabel Mosquera, Eric Lucas, Mary Luz Rol et al.
The CanScreen5 project is a global cancer screening data repository that aims to report the status and performance of breast, cervical and colorectal cancer screening programs using a harmonized set of criteria and indicators. Data collected mainly from the Ministry of Health in each country underwe...
Phuong Hong Nguyen, Edward A. Frongillo, Tina Sanghvi, Gargi Wable Grandner et al.
Background: Although husbands may provide support during pregnancy, limited evidence exists on how to promote husbands' engagement and what impact it has. Alive & Thrive integrated nutrition-focused interventions, targeting both wives and husbands, through an existing Maternal, Neonatal, and Child H...
Sunny S. Kim, Phuong Hong Nguyen, Lan Mai Tran, Tina Sanghvi et al.
Background: Sustained improvements in infant and young child feeding (IYCF) require continued implementation of effective interventions. From 2010-2014, Alive & Thrive (A&T) provided intensive interpersonal counseling (IPC), community mobilization (CM), and mass media (MM) in Bangladesh, demonstrati...
Marie Loh, Weihua Zhang, Hong Kiat Ng, Katharina Schmid et al.
Abstract South Asians are at high risk of developing type 2 diabetes (T2D). We carried out a genome-wide association meta-analysis with South Asian T2D cases ( n = 16,677) and controls ( n = 33,856), followed by combined analyses with Europeans (n eff = 231,420). We identify 21 novel genetic loci fo...
Kar Hau Chong, Thomas Suesse, Penny Cross, Sarah T. Ryan et al.
Importance: The prevalence estimates of physical activity, sedentary behavior, and sleep (collectively known as movement behaviors) in 3- and 4-year-old children worldwide remains uncertain. Objective: To report the proportion of 3- and 4-year-old children who met the World Health Organization guide...
Kenneth S. Gunasekera, Olivier Marcy, Johanna Muñoz, Elisa López‐Varela et al.
BACKGROUND: Many children with pulmonary tuberculosis remain undiagnosed and untreated with related high morbidity and mortality. Recent advances in childhood tuberculosis algorithm development have incorporated prediction modelling, but studies so far have been small and localised, with limited gen...