Tushar Emran, Nowreen Islam Chowdhury, Manoneeta Sarker, Asim Kumar Bepari et al.
BRIEF INTRODUCTION: Myocardial infarction (MI) is a common manifestation of certain cardiac diseases where oxidative stress and fibrosis aggravate the condition markedly. MAIN OBJECTIVE OF THE STUDY: Investigation of L-carnitine's cardioprotective roles and mechanism of action in a rat model of MI. ...
Mohammad Hossain Shariare, Mohammad A. Altamimi, Akbar L. Marzan, Rahnuma Tabassum et al.
BACKGROUND: performance of furosemide nanosuspensions. METHODS: dissolution experiments were conducted to compare the representative formulation with raw drug powder. The bioavailability of nanosuspension was, also, evaluated in mice as an animal model. RESULTS: about 233% and 266%, respectively. Th...
Md Mizanur Rahman, Awale Yousuf Muse, Mohammad Zubair Khan, Ismaile Hussein Ahmed et al.
Background Liver fibrosis is a leading pathway to cirrhosis and a global clinical issue. Oxidative stress mediated tissue damage is one of the prime causes of hepatic dysfunction and fibrosis. Apocynin is one of many strong antioxidants. Objective To evaluate the effect of apocynin in the CCl 4 admi...
Syed Rashel Kabir, Md. Mahamodun Nabi, Md. Nurujjaman, Md Abu Reza et al.
In last three decades, several studies were carried out on the D-galactose-specific lectin of Momordica charantia seeds (MCL). In the present study, in vitro growth inhibition (8-23 %) at different concentrations (6-24 μg/ml) of MCL was observed against Ehrlich ascites carcinoma (EAC) cells by 3-(4,...
A M Mahmudul Hasan, Md. Akib Hasan, Atek Reza, Md. Mominul Islam et al.
Mithun Saha, Diti Rani Saha, Tahamina Ulhosna, Shazid Md. Sharker et al.
The lower drug retention to the eye's anterior portion is a prime concern in the ocular drug delivery system. To improve the drug retention capacity, we aimed to develop drug–containing nanoparticles using Quality by Design (QbD) approach. The current study describes the development of resveratrol-l...
Bimol Nath Roy, Hridoy Roy, Kazi Saidur Rahman, Foysal Mahmud et al.
• Available river WQA studies in Dhaka are concerned with spatial and temporal changes. • Correlation analysis followed by PCA can effectively reduce the number of parameters. • A WQI model was developed with 7 reduced WQPs from 12 WQPs for Dhaka-based rivers. • WQI for the rivers ranged from 36 to ...
Md. Aminul Islam, Foysal Hossen, Md Arifur Rahman, Khandokar Fahmida Sultana et al.
Wastewater-Based Epidemiological Monitoring (WBEM) is an efficient surveillance tool during the COVID-19 pandemic as it meets all requirements of a complete monitoring system including early warning, tracking the current trend, prevalence of the disease, detection of genetic diversity as well asthe ...
Partha Biswas, Dipta Dey, Atikur Rahman, Md. Aminul Islam et al.
BACKGROUND: SYK gene regulates the expression of SYK kinase (Spleen tyrosine kinase), an important non-receptor protein-tyrosine kinase for immunological receptor-mediated signaling, which is also considered a tumor growth metastasis initiator. An onco-informatics analysis was adopted to evaluate th...
Samanta Sifat Lamia, Tushar Emran, Jubaida Khatun Rikta, Nowreen Islam Chowdhury et al.
Oxidative stress is one of the key factors in the pathophysiology of liver disease. The present study aimed to evaluate the potential impact of two antioxidants, namely coenzyme Q10 (CoQ10) and silymarin, on carbon tetrachloride (CCl4)-induced oxidative stress and hepatic damage in ovariectomized ra...
Asim Kumar Bepari, Hasan Mahmud Reza
BACKGROUND: The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has ravaged lives across the globe since December 2019, and new cases are still on the rise. Peoples' ongoing sufferings trigger scientists to develop safe and effective remedies to treat this deadly viral disease. While repurposing ...
Fatima Tuj Johra, Sukria Hossain, Preeti Jain, Anika Tabassum Bristy et al.
Abstract Liver disease is a serious health problem affecting people worldwide at an alarming rate. The present study aimed to investigate the protective effects of Ganoderma lucidum against CCl 4 -induced liver toxicity in rats. The experimental Long Evans rats were divided into five groups, of whic...
Artyom Zinchenko, Md. Mamun Al-Amin, Musrura Mefta Alam, Waich Mahmud et al.
Background Attentional bias to affective information and reduced cognitive control may maintain the symptoms of post-traumatic stress disorder (PTSD) and impair cognitive functioning. However, the role of content specificity of affective stimuli (e.g., trauma-related, emotional trauma-unrelated) in ...
Kazi Mahmud Hasan, Abdullah-Al Nahid, Khondker Jahid Reza, Sabira Khatun et al.
This paper introduces the multiple source Multiple Destination Robot (MDR-l) having the ability to choose a desired line among multiple lines autonomously. Every line has different colors as their identities. The robot can differentiate among various colors and choose a desired one to find its targe...
Md. Mamun Al-Amin, Md. Faiyad Rahman Choudhury, Al Saad Chowdhury, Tahsinur Rahman Chowdhury et al.
Risperidone (RIS), an atypical antipsychotic has been found to show anti-inflammatory effect against lipopolysaccharide (LPS)-induced inflammation. In-vitro study has revealed that RIS inhibits the LPS-induced reactive oxygen species (ROS) formation. We investigated the antioxidant effects of RIS on...