Jieyu Qi, Liyan Zhang, Ling Lü, Fangzhi Tan et al.
Gene therapy for congenital deafness has shown promising results in children but lacks data in older populations. We conducted a single-arm trial of adeno-associated virus (AAV)-OTOF gene therapy using the Anc80L65 capsid in ten participants with autosomal recessive deafness 9 aged 1.5 to 23.9 years...
Yangbo Ma, Liang Guo, Liang Chang, Weihua Guo et al.
Tandem catalysis is an effective approach to achieve highly selective and high-rate multi-electron/proton transfer reactions, such as nitrate electroreduction, which are important for various physicochemical and biological processes. However, present tandem catalysts suffer from uncontrollable inter...
Jia Wang, Jiechen Yin, Danhong Peng, Xiaoqian Zhang et al.
4-Nitrophenol (4-NP), as a toxic and refractory pollutant, has generated significant concern due to its adverse effects. However, the potential toxic effects and mechanism remained unclear. In this study, the reproduction, development, locomotion and reactive oxygen species (ROS) production of Caeno...
Yi-Han Iris Yin, Bin‐Bin Zhang, Jun Yang, Hui Sun et al.
Abstract The Einstein Probe (EP) achieved its first detection and localization of a bright X-ray flare, EP240219a, on 2024 February 19, during its commissioning phase. Subsequent targeted searches triggered by the EP240219a alert identified a faint, untriggered gamma-ray burst (GRB) in the archived ...
Kwadwo Gyapong Agyenim‐Boateng, Shengrui Zhang, Md Shariful Islam, Yongzhe Gu et al.
Soybean is a rich source of folates. We optimised the extraction and detection of folates from soybean seeds by HPLC-MS/MS and analysed the folate content and composition of 1074 accessions. Total folate content ranged from 64.51 to 691.24 μg/100 g fresh weight, with 10-fold variation, and 60 elite ...
Zhimin Wang, Ding Zhou, Zili Zhou, Wenbin Gong et al.
Abstract Aqueous zinc‐ion batteries (AZIBs) with the merits of superior security, natural abundance, and inexpensive Zn hold great promises for next‐generation energy storage. Nevertheless, the instabilities of the Zn anodes arising from the unsatisfactory dendrite growth and parasitic reactions hav...
Juan Yin, Jing Wang, Xinxin Zhang, Yan Liao et al.
Abstract Background Pulmonary fibrosis initiates a pneumonic cascade that leads to fibroblast dysfunction characterized by excess proliferation. Anoikis is a physiological process that ensures tissue development and homeostasis. Researchers have not clearly determined whether disruption of anoikis i...
Ji Zhang, Xinpu Lu, Yinzi Jin, Zhi‐Jie Zheng
The WHO declared the coronavirus disease 2019 (COVID-19) outbreak as a public health emergency of international concern on January 30, 2020, and then a pandemic on March 11, 2020. COVID-19 affected over 200 countries and territories worldwide, with 25,541,380 confirmed cases and 852,000 deaths assoc...
Aftab Amin, Muhammad Jahangir Hossen, Xiu‐Qiong Fu, Ji‐Yao Chou et al.
ETHNOPHARMACOLOGICAL RELEVANCE Gastritis can lead to ulcers and the development of gastric cancer. The rhizome of Atractylodes macrochepala Koidz. (Asteraceae), a traditional Chinese medicinal herb, is prescribed for the treatment of gastric disorders, hepatitis and rheumatism. Its bio-active compou...
Ying Li, Shengke Yang, Qianli Jiang, Jie Fang et al.
The sludge from the water supply plant was investigated to remove fluoride ions from the water. To improve the adsorption ability, the original sludge sample was treated with fuel oxidation, pyrolysis, hydrochloric acid, and sulphuric acid methods, and hydrochloric acid treatment improved the adsorp...
Zhaoyang Wang, Jie Cheng, Ying Wang, Haitao Yuan et al.
Imbalance of proinflammatory and anti-inflammatory responses plays a crucial role in the progression of abdominal aortic aneurysms. ILF3, a known modulator of the innate immune response, is involved in cardiovascular diseases. This study aims to investigate the role of ILF3 in abdominal aortic aneur...
Rui Huang, Li Xia Zhu, Leyang Xue, Longgen Liu et al.
Hou‐Qun Ying, Jie Wang, Xueren Gao
Associations between CCL5-403, CCR5-59029, and Delta32 polymorphisms and cancer risk are inconclusive. To derive a more precise estimation of the association, we performed a meta-analysis by searching PubMed, EMBASE, Google scholar, and WanFang databases. A total of 20 eligible articles with 39 stud...
Lulu Zhao, Jun-Wei Yin, Bingchen Liu, Peng‐Fei Wang et al.
In recent years, aqueous zinc ion batteries (AZIBs) with the benefits of high safety, low cost, high capacity and environmental protection, have broad development prospects in the area of massive energy storage. Among them, MnO2 materials are seen to be the most prospective cathode materials because...
Jie Xiong, Yuerong Wang, Cuizhen Yang, Lu Yang et al.
Although metallic rhodium (Rh) is regarded as a promising platinum (Pt)-alternative electrode used in direct methanol fuel cell technology, its electrocatalytic ability still needs to be substantially improved before large-scale commercial applications. Herein, we report a bottom-up design strategy ...