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Results for “"Amer H. Asseri"”

12 results

Application of Mathematical Modeling and Computational Tools in the Modern Drug Design and Development Process

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Md. Rifat Hasan, Ahad Amer Alsaiari, Burhan Zain Fakhurji, Mohammad Habibur Rahman Molla et al.

Journal: MoleculesYear: 2022Citations: 93

The conventional drug discovery approach is an expensive and time-consuming process, but its limitations have been overcome with the help of mathematical modeling and computational drug design approaches. Previously, finding a small molecular candidate as a drug against a disease was very costly and...

Physical SciencesComputer ScienceComputational Theory and MathematicsOpen Access
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Integrative Ligand-Based Pharmacophore Modeling, Virtual Screening, and Molecular Docking Simulation Approaches Identified Potential Lead Compounds against Pancreatic Cancer by Targeting FAK1

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Mohammad Habibur Rahman Molla, Mohammed Othman Aljahdali, Md Afsar Ahmed Sumon, Amer H. Asseri et al.

Journal: PharmaceuticalsYear: 2023Citations: 45

Pancreatic cancer is a very deadly disease with a 5-year survival rate, making it one of the leading causes of cancer-related deaths globally. Focal adhesion kinase 1 (FAK1) is a ubiquitously expressed protein in pancreatic cancer. FAK, a tyrosine kinase that is overexpressed in cancer cells, is cru...

Physical SciencesMaterials ScienceBiomaterialsOpen Access
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Epigenetics and Probiotics Application toward the Modulation of Fish Reproductive Performance

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Md Afsar Ahmed Sumon, Mohammad Habibur Rahman Molla, Israa J. Hakeem, Foysal Ahammad et al.

Journal: FishesYear: 2022Citations: 28

Fish represent an excellent source of animal protein as well as a biomedical research model as a result of their evolutionary relatedness and similarity with the human genome. Commercial and ornamental fish culture has achieved popularity, but reproductive dysfunctions act as a limiting factor for q...

Life SciencesBiochemistry, Genetics and Molecular BiologyPhysiologyOpen Access
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Toward the Identification of Natural Antiviral Drug Candidates against Merkel Cell Polyomavirus: Computational Drug Design Approaches

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Amer H. Asseri, Md. Jahidul Alam, Faisal A. Alzahrani, Ahmed Khames et al.

Journal: PharmaceuticalsYear: 2022Citations: 22

Merkel cell carcinoma (MCC) is a rare form of aggressive skin cancer mainly caused by Merkel cell polyomavirus (MCPyV). Most MCC tumors express MCPyV large T (LT) antigens and play an important role in the growth-promoting activities of oncoproteins. Truncated LT promotes tumorigenicity as well as h...

Health SciencesMedicineOncologyOpen Access
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Identification of natural antiviral drug candidates against Tilapia Lake Virus: Computational drug design approaches

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Md Afsar Ahmed Sumon, Amer H. Asseri, Mohammad Habibur Rahman Molla, Mohammed Othman Aljahdali et al.

Journal: PLoS ONEYear: 2023Citations: 14

Tilapia Lake Virus (TiLV) is a disease that affects tilapia fish, causing a high rate of sudden death at any stage in their life cycle. Unfortunately, there are currently no effective antiviral drugs or vaccines to prevent or control the progression of this disease. Researchers have discovered that ...

Health SciencesMedicinePublic Health, Environmental and Occupational HealthOpen Access
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Integrated structure model-based virtual screening approaches identified anti-cancer agents against prostate cancer by targeting MAOB protein

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Mohammad Habibur Rahman Molla, Amer H. Asseri, Md. Shafiqul Islam

Journal: Egyptian Journal of Medical Human GeneticsYear: 2023Citations: 10

Abstract Background Flavin monoamine oxidase gene encodes a protein (MAOB) that forms a part of the flavin monoamine oxidase family in the outer membrane of mitochondria. It plays a role in the tissue metabolism of neuroactive and vasoactive amines as well as the oxidative deamination of xenobiotic ...

Physical SciencesComputer ScienceComputational Theory and MathematicsOpen Access
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Effects of environmental enrichments on ovarian development of Buitta Catfish (Sperata sp.: Family Bagridae) in captivity

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Md Afsar Ahmed Sumon, Mahbuba khanam, Muhammad Anamul Kabir, Zulhisyam Abdul Kari et al.

Journal: The Egyptian Journal of Aquatic ResearchYear: 2022Citations: 8

Environmental enrichment (EE) is an important factor that helps improve both the physical and psychological behavior of farmed animals. This factor also controls social interactions and provides more stimulants to influence the reproductive performance of animals in captivity. As EE plays an importa...

Life SciencesBiochemistry, Genetics and Molecular BiologyPhysiologyOpen Access
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Diversity and seasonal succession of resident and migratory macrobenthic fauna of saltmarsh restoration site at Sonadia Island, Cox’s Bazar, Bangladesh

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Md Shafiqul Islam, Alam Pervez, Amer H. Asseri, Mohammed Al-Mutair et al.

Journal: Regional Studies in Marine ScienceYear: 2022Citations: 7
Physical SciencesEnvironmental ScienceEcology
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Bioaccumulation of heavy metals in water and mollusks in the Karnafully estuary: Potential human health risk and environmental contamination

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Humayra Kabir Niloy, Aminul Islam Chowdhury, Md Shafiqul Islam, Alam Pervez et al.

Journal: Regional Studies in Marine ScienceYear: 2024Citations: 5
Physical SciencesEnvironmental SciencePollution
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A systematic analysis of ATPase Cation transporting 13A2 (ATP13A2) transcriptional expression and prognostic value in human brain cancer

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Rahat Alam, Sattyajit Biswas, Farhana Haque, Mohammad Turhan Pathan et al.

Journal: Biomedical Signal Processing and ControlYear: 2021Citations: 5

P-type transport ATPase’s are active transporters that dispense the majority of the cellular functions. ATP13A2 have a role in neurodegeneration which is commonly associated with lysosomal dysfunction. Lysosome plays a significant role in the metabolism, secretion, signaling, plasma membrane repair,...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Biology
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Identification of Natural Antiviral Drug Candidates Against Tilapia Lake Virus: Computational Drug Design Approaches

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Md Afsar Ahmed Sumon, Amer H. Asseri, Mohammad Habibur Rahman Molla, Mohammed Othman Aljahdali et al.

Journal: bioRxiv (Cold Spring Harbor Laboratory)Year: 2023Citations: 3

Abstract Tilapia Lake Virus (TiLV) is a disease that affects tilapia fish, causing a high rate of sudden death at any stage of their growth. Unfortunately, there are currently no effective antiviral drugs or vaccines to control the progression of this disease. Researchers have discovered that the CR...

Physical SciencesComputer ScienceComputational Theory and MathematicsOpen Access
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Identification of natural antimicrobial peptides mimetic to inhibit Ca2+ influx DDX3X activity for blocking dengue viral infectivity

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Amer H. Asseri, Md Rashedul Islam, Reem M. Alghamdi, Hisham N. Altayb

Journal: Journal of Bioenergetics and BiomembranesYear: 2023Citations: 1

Viruses are microscopic biological entities that can quickly invade and multiply in a living organism. Each year, over 36,000 people die and nearly 400 million are infected with the dengue virus (DENV). Despite dengue being an endemic disease, no targeted and effective antiviral peptide resource is ...

Life SciencesImmunology and MicrobiologyMicrobiology
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