Jingcheng Dai, Aijun Dong, Guoxi Xiong, Yaqi Liu et al.
In this study, a series of bacteria capable of degrading starch and cellulose were isolated from the aging flue-cured tobacco leaves. Remarkably, there was a thermophilic bacterium Bacillus subtilis ZIM3 which can simultaneously degrade both starch and cellulose at a wide range of temperature and pH...
Qian Li, Liwen Yu, Amy Gao, Ruiqing Ren et al.
Background: Atherosclerosis is a chronic inflammatory disease, in which macrophages determine the progression of atherosclerotic plaques. However, no studies have investigated how METTL3 (methyltransferase like 3) in macrophages affects atherosclerotic plaque formation in vivo. Additionally, whether...
Aislinn Cook, Laura Ferreras, B. Adhisivam, Daynia Ballot et al.
Neonatal invasive candidiasis (NIC) has significant morbidity and mortality. Reports have shown a different profile of those neonates affected with NIC and of fluconazole-resistant Candida spp. isolates in low- and middle-income countries (LMICs) compared to high-income countries (HICs). We describe...
Liwen Yu, Jie Zhang, Amy Gao, Meng Zhang et al.
Abstract The developmental origin, anatomical location, and other factors contribute to aortic heterogeneity in a physiological state. On this basis, vascular diseases occur at different ratios based on position specificity, even with the same risk factor. However, the continuous intersegmental aort...
Lei Gao, Peng Li, Arlen Gaba, Erik S. Musiek et al.
Abstract Introduction Degradation in fractal motor activity regulation (FMAR), a measure of multiscale self‐similarity of motor control, occurs in aging and accelerates with clinical progression to Alzheimer's disease (AD). Whether FMAR changes occur during the pre‐symptomatic phase of the disease i...
Kevin Sun, Xiao Li, Xing Chen, Ying Bai et al.
Human Ag R (HuR) is an RNA binding protein in the ELAVL protein family. To study the neuron-specific function of HuR, we generated inducible, neuron-specific HuR-deficient mice of both sexes. After tamoxifen-induced deletion of HuR, these mice developed a phenotype consisting of poor balance, decrea...
Jie Zhang, Lei Cao, Amy Gao, Ruiqing Ren et al.
Innate immunity is the first line to defend against pathogenic microorganisms, and Toll-like receptor (TLR)-mediated inflammatory responses are an essential component of innate immunity. However, the regulatory mechanisms of TLRs in innate immunity remain unperfected. We found that the expression of...
Yu‐Chen Chen, Xiaowei Li, Lijie Liu, Jian Wang et al.
Full text Figures and data Side by side Abstract eLife digest Introduction Results Discussion Materials and methods References Decision letter Author response Article and author information Metrics Abstract Hearing loss often triggers an inescapable buzz (tinnitus) and causes everyday sounds to beco...
Chaowen Zheng, X Liu, Anqi Wei, Bing Liu et al.
Exploration is a fundamental innate behavior essential for securing survival-necessary resources, but it also increases risks. However, the neural mechanisms encoding exploration decisions remain unknown. Here, we show that social companionship motivates both innate-driven and experience-dependent e...