CARDIoGRAMplusC4D, Joanna M. M. Howson, EPIC-CVD, Wei Zhao et al.
Coronary artery disease (CAD) is a leading cause of morbidity and mortality worldwide. Although 58 genomic regions have been associated with CAD thus far, most of the heritability is unexplained, indicating that additional susceptibility loci await identification. An efficient discovery strategy may...
Wei Zhao, Asif Rasheed, Emmi Tikkanen, Jung‐Jin Lee et al.
To evaluate the shared genetic etiology of type 2 diabetes (T2D) and coronary heart disease (CHD), we conducted a genome-wide, multi-ancestry study of genetic variation for both diseases in up to 265,678 subjects for T2D and 260,365 subjects for CHD. We identify 16 previously unreported loci for T2D...
Gary L. Darmstadt, Samir K. Saha, ASM Nawshad Uddin Ahmed, MAK Azad Chowdhury et al.
Background Infections and complications of prematurity are main causes of neonatal mortality. Very low birthweight premature infants have compromised skin barrier function, and are at especially high risk for serious infections and mortality. Our aim was to ascertain whether topical application of e...
Sayedus Salehin, Mohammad Tanvirul Ferdaous, Ridhwan M. Chowdhury, Sumaia Shahid Shithi et al.
Ahmed Rakib, Saad Ahmed Sami, Nusrat Jahan Mimi, Md. Mustafiz Chowdhury et al.
Aims With a large number of fatalities, coronavirus disease-2019 (COVID-19) has greatly affected human health worldwide. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus that causes COVID-19. The World Health Organization has declared a global pandemic of this contagious dis...
Tasnima Haque, Khondoker Moazzem Hossain, Md. Monzur Rahman Bhuiyan, Sadia Afreen Ananna et al.
<title>Abstract</title> The COVID19 pandemic has been transmitted worldwide rapidly. The best ways of preventing this virus are to know about and act accordingly. An online cross sectional survey was conducted to know the knowledge, attitude and practices towards COVID19 and to assess the risks of i...
Md. Zubair, Md Asif Iqbal, Avijeet Shil, Mohammad Jabed Morshed Chowdhury et al.
K-means algorithm is one of the well-known unsupervised machine learning algorithms. The algorithm typically finds out distinct non-overlapping clusters in which each point is assigned to a group. The minimum squared distance technique distributes each point to the nearest clusters or subgroups. One...
Zarrin Tasnim, Sovon Chakraborty, F. M. Javed Mehedi Shamrat, Ali Newaz Chowdhury et al.
In recent years, the area of Medicine and Healthcare has made significant advances with the assistance of computational technology. During this time, new diagnostic techniques were developed. Cancer is the world's second-largest cause of mortality, claiming the lives of one out of every six individu...
Gary L. Darmstadt, ASM Nawshad Uddin Ahmed, Samir K. Saha, M. A. K. Azad Chowdhury et al.
Objective The skin is a potential source for invasive infections in neonates from developing countries such as Bangladesh, where the level of environmental contamination is exceedingly high. A randomized controlled trial was conducted from 1998 to 2003 in the Special Care Nursery of a tertiary hospi...
Zeaur Rahim, S. C. Sanyal, K M Aziz, Mohsina Huq et al.
Strains of Aeromonas hydrophila isolated from skin infections of common freshwater fish in Bangladesh were tested for enterotoxin production, hemolysin production, and any correlation between these two activities. We also tested the resistance patterns of A. hydrophila to different drugs, especially...
Md. Arif Hossen, Ahnaf Ismam Haque Chowdhury, Md. Reaz Akter Mullick, Asiful Hoque
Tapos Kumar Chakraborty, Md Jahid Hasan, Baytune Nahar Netema, Md Abu Rayhan et al.
Microplastics (MPs) are polymer-based particles commonly found in diverse foods that pose serious human health impacts throughout the food chain. Assessment of MPs in different food products is a prime measure to combat MP-related food contamination. Therefore, this study first investigated the iden...
Md. Sazzad Hossain, Md. Asif Haider Khan, Tomiwa V. Oluwajuwon, Jayanta Biswas et al.
Abstract Land cover change has posed significant concerns to biodiversity and climate change in Bangladesh and globally. Despite the country’s designation of forest regions as protected areas to conserve their valuable resources, deforestation and forest conversion remained unabated. Fashiakhali Wil...
Tapos Kumar Chakraborty, Md Sozibur Rahman, Md. Simoon Nice, Baytune Nahar Netema et al.
Microplastics (MPs) are an emerging global concern due to severe toxicological risks for ecosystems and public health. Therefore, this is the first study in Bangladesh to assess MP pollution and its associated risks for ecosystems and human health in the outdoor urban environment using machine learn...
Jeffrey D. Wall, J. Fah Sathirapongsasuti, Ravi Gupta, Asif Rasheed et al.
The benefits of large-scale genetic studies for healthcare of the populations studied are well documented, but these genetic studies have traditionally ignored people from some parts of the world, such as South Asia. Here we describe whole genome sequence (WGS) data from 4806 individuals recruited f...
Ismat Bhuiya, Ubaidur Rob, Asiful Chowdhury, Laila Rahman et al.
An operations research project was launched in northwestern Bangladesh with the objective of preventing adverse outcomes and promoting healthy lifestyles among adolescents by providing reproductive health education and services. The Population Council, in collaboration with the Urban Family Health P...
Chowdhury Faiz Hossain, Mohammad Al‐Amin, Abu Sadat Md. Sayem, Ismail Hossain Siragee et al.
BACKGROUND: The rhizome of Curcuma aeruginosa Roxb (Zingiberaceae) has been used as a traditional folk medicine for the treatment of rheumatic disorders in Bangladesh. The aim of the current study was the bioassay-guided isolation and purification of an antinociceptive principle from the methanol ex...
Afroza Akter, Tasnuva Ahmed, Imam Tauheed, Marjahan Akhtar et al.
BACKGROUND: COVID-19 caused by SARS-CoV-2 ranges from asymptomatic to severe disease and can cause fatal and devastating outcome in many cases. In this study, we have compared the clinical, biochemical and immunological parameters across the different disease spectrum of COVID-19 in Bangladeshi pati...
Asiful Haidar Chowdhury, Syed Manzoor Ahmed Hanifi, Mohammad Nahid Mia, Abbas Bhuiya
BACKGROUND: Socioeconomic inequality in health and mortality remains a disturbing reality across nations including Bangladesh. Inequality drew renewed attention globally. Bangladesh though made impressive progress in health, it makes an interesting case for learning. This paper examined the trends a...
Md. Rakhibul Hasan, Surid Mohammad Chowdhury, Md. Abdul Aziz, Asif Shahriar et al.
In this in silico study, thirty-five ciprofloxacin analogs were docked to the active site of DNA gyrase, the prime target of ciprofloxacin type antibiotics. Prior to docking all the structures were optimized using MM2 force field parameters. The study revealed that five candidates, namely 6MePQ_3, 6...