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Results for “"Chanchan Gao"”

3 results

Immunomodulatory effects of chemotherapy on blood lymphocytes and survival of patients with advanced non-small cell lung cancer

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Mohanad Aldarouish, Xiangyu Su, Jianbing Qiao, Chanchan Gao et al.

Journal: International Journal of Immunopathology and PharmacologyYear: 2019Citations: 36

A better understanding of the immune profile of non-small cell lung cancer (NSCLC) and the immunomodulatory impact of chemotherapy is essential to develop current therapeutic approaches. Herein, we collected peripheral blood from 20 healthy donors and 50 patients with advanced NSCLC, before and afte...

Life SciencesImmunology and MicrobiologyImmunologyOpen Access
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Enhancing Breast Cancer Immunotherapy by Suppressing Sympathetic Nervous System-Driven T-Cell Exhaustion and Promoting T-Cell Priming and Trafficking

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Lin Gao, Zhiyuan Luo, Lei Dong, Chanchan Gao et al.

Journal: ACS NanoYear: 2025Citations: 2

Immunotherapy has transformed cancer treatment, yet its efficacy in solid tumors such as breast cancer remains limited by weak T cell priming, impaired trafficking, and functional exhaustion within the tumor microenvironment. Sympathetic nervous system (SNS) hyperactivation has recently emerged as a...

Health SciencesMedicinePsychiatry and Mental health
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Macrophage Membrane-Engineered Nanovesicles Co-Delivering Ruxolitinib and Carvedilol for Synergistic Therapy of Cisplatin-Resistant Lung Cancer

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Chanchan Gao, Zhengcheng Yun, Xinyue Bai, P H Wang et al.

Journal: ACS Applied Nano MaterialsYear: 2026

Lung cancer is the leading cause of cancer death worldwide, and nonsmall cell lung cancer is the most common type. Cisplatin-based chemotherapy is still the cornerstone therapy for many patients, but its efficacy is often limited by the emergence of drug resistance, which makes it crucial to find st...

MedicineLung cancerCisplatin
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