Xiaohu You, Cheng‐Xiang Wang, Jie Huang, Xiqi Gao et al.
Abstract The fifth generation (5G) wireless communication networks are being deployed worldwide from 2020 and more capabilities are in the process of being standardized, such as mass connectivity, ultra-reliability, and guaranteed low latency. However, 5G will not meet all requirements of the future...
Taotao Li, Wei Guo, Liang Ma, Weisheng Li et al.
Two-dimensional (2D) semiconductors, in particular transition metal dichalcogenides (TMDCs), have attracted great interest in extending Moore's law beyond silicon 1-3 . However, despite extensive efforts 4-25 , the growth of wafer-scale TMDC single crystals on scalable and industry-compatible substr...
Charge Diabetes Working Group, Dajiang J. Liu, VA Million Veteran Program, Gina M. Peloso et al.
We screened variants on an exome-focused genotyping array in >300,000 participants (replication in >280,000 participants) and identified 444 independent variants in 250 loci significantly associated with total cholesterol (TC), high-density-lipoprotein cholesterol (HDL-C), low-density-lipoprotein ch...
Norihiro Kato, CARDIo GRAMplusCD, LifeLines Cohort Study, Marie Loh et al.
We carried out a trans-ancestry genome-wide association and replication study of blood pressure phenotypes among up to 320,251 individuals of East Asian, European and South Asian ancestry. We find genetic variants at 12 new loci to be associated with blood pressure (P = 3.9 × 10−11 to 5.0 × 10−21). ...
Wa Gao, Li Shi, Huichao He, Xiaoning Li et al.
Abstract Artificial photosynthesis, light-driving CO 2 conversion into hydrocarbon fuels, is a promising strategy to synchronously overcome global warming and energy-supply issues. The quaternary AgInP 2 S 6 atomic layer with the thickness of ~ 0.70 nm were successfully synthesized through facile ul...
Yuan Liu, Yuting Shen, Litao Sun, Jincheng Li et al.
Doping of low-dimensional graphitic materials, including graphene, graphene quantum dots and single-wall carbon nanotubes with nitrogen, sulfur or boron can significantly change their properties. We report that simple fluorination followed by annealing in a dopant source can superdope low-dimensiona...
Jiadong Zhou, Chao Zhu, Yao Zhou, Jichen Dong et al.
Two-dimensional (2D) materials with multiphase, multielement crystals such as transition metal chalcogenides (TMCs) (based on V, Cr, Mn, Fe, Cd, Pt and Pd) and transition metal phosphorous chalcogenides (TMPCs) offer a unique platform to explore novel physical phenomena. However, the synthesis of a ...
Zhifa Wen, Hongxiang Liu, Rong Gao, Meng Zhou et al.
<h3>Background</h3> Tumor-associated macrophages (TAMs) facilitate tumor progression via establishment of an immunosuppressive tumor microenvironment (TME). However, it is poorly understood how tumor cells could functionally modulate TAMs. Our previous work indicated that tumor cell-released autopha...
Victor Ongoma, Haishan Chen, Chujie Gao
ABSTRACT This study presents potential future variations of mean rainfall and temperature over East Africa (EA) based on five models that participated in the Coupled Model Intercomparison Project Phase 5 (CMIP5) and representative concentration pathways (RCPs): 4.5 and 8.5. In this study, climate si...
David T. S. Hayman, Wiku Adisasmito, Salama Almuhairi, Casey Barton Behravesh et al.
The health of humans, domestic and wild animals, plants, and the environment are inter-dependent. Global anthropogenic change is a key driver of disease emergence and spread and leads to biodiversity loss and ecosystem function degradation, which are themselves drivers of disease emergence. Pathogen...
Hong Zhuang, Xiuting Yao, Hong Li, Qian Li et al.
High-fat diet (HFD) consumption is generally associated with an increased risk of cognitive and emotional dysfunctions that constitute a sizeable worldwide health burden with profound social and economic consequences. Middle age is a critical time period that affects one's health later in life; pert...
Jie Xu, Yibing Yuan, Yunbi Xu, Gengyun Zhang et al.
BACKGROUND: Drought stress is one of the major limiting factors for maize production. With the availability of maize B73 reference genome and whole-genome resequencing of 15 maize inbreds, common variants (CV) and clustering analyses were applied to identify non-synonymous SNPs (nsSNPs) and correspo...
Kamala Thriemer, Albino Bobogare, Benedikt Ley, Clarice Samo Gudo et al.
The goal to eliminate malaria from the Asia-Pacific by 2030 will require the safe and widespread delivery of effective radical cure of malaria. In October 2017, the Asia Pacific Malaria Elimination Network Vivax Working Group met to discuss the impediments to primaquine (PQ) radical cure, how these ...
Lei Wang, Changyong Yang, Chengying Xie, Jiahua Jiang et al.
Poly( ADP ‐ribose) polymerase ( PARP ) enzymes play an important role in repairing DNA damage and maintaining genomic stability. Olaparib, the first‐in‐class PARP inhibitor, has shown remarkable clinical benefits in the treatment of BRCA ‐mutated ovarian or breast cancer. However, the undesirable he...
Wei Zhang, Ming Luo, Si Gao, Wei‐Lin Chen et al.
Compound extremes pose immense challenges and hazards to communities, and this is particularly true for compound hydrometeorological extremes associated with deadly floods, surges, droughts, and heat waves. To mitigate and better adapt to compound hydrometeorological extremes, we need to better unde...