Marie Ng, Tom Fleming, Margaret S. Robinson, Blake Thomson et al.
Background In 2010, overweight and obesity were estimated to cause 3.4 million deaths, 3.9% of years of life lost, and 3.8% of DALYs globally. The rise in obesity has led to widespread calls for regular monitoring of changes in overweight and obesity prevalence in all populations. Comparative, up-to...
Christina Fitzmaurice, Degu Abate, Naghmeh Abbasi, Hedayat Abbastabar et al.
<h3>Importance</h3> Cancer and other noncommunicable diseases (NCDs) are now widely recognized as a threat to global development. The latest United Nations high-level meeting on NCDs reaffirmed this observation and also highlighted the slow progress in meeting the 2011 Political Declaration on the P...
Christopher J L Murray, Ryan M Barber, Kyle J Foreman, Ayşe Abbasoğlu Özgören et al.
Background The Global Burden of Disease Study 2013 (GBD 2013) aims to bring together all available epidemiological data using a coherent measurement framework, standardised estimation methods, and transparent data sources to enable comparisons of health loss over time and across causes, age–sex grou...
Christopher J L Murray, Cristiana Abbafati, Kaja Abbas, Mohammad Hossein Abbasi et al.
The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a rules-based synthesis of the available evidence on levels and trends in health outcomes, a diverse set of risk factors, and health system responses. GBD 2019 covered 204 countries and territories, as well as first ...
Luregn J. Schlapbach, R. Scott Watson, Lauren R. Sorce, Andrew C. Argent et al.
Importance: Sepsis is a leading cause of death among children worldwide. Current pediatric-specific criteria for sepsis were published in 2005 based on expert opinion. In 2016, the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) defined sepsis as life-threatening org...
Guillaume Émériaud, Yolanda M. López‐Fernández, Narayan P. Iyer, Melania M. Bembea et al.
OBJECTIVES: We sought to update our 2015 work in the Second Pediatric Acute Lung Injury Consensus Conference (PALICC-2) guidelines for the diagnosis and management of pediatric acute respiratory distress syndrome (PARDS), considering new evidence and topic areas that were not previously addressed. D...
Joris Deelen, Marian Beekman, Hae‐Won Uh, Linda Broer et al.
The genetic contribution to the variation in human lifespan is ∼ 25%. Despite the large number of identified disease-susceptibility loci, it is not known which loci influence population mortality. We performed a genome-wide association meta-analysis of 7729 long-lived individuals of European descent...
L. Nelson Sanchez‐Pinto, Tellen D. Bennett, Peter E. DeWitt, Seth Russell et al.
Importance: The Society of Critical Care Medicine Pediatric Sepsis Definition Task Force sought to develop and validate new clinical criteria for pediatric sepsis and septic shock using measures of organ dysfunction through a data-driven approach. Objective: To derive and validate novel criteria for...
Adrian Leftwich
Click to increase image sizeClick to decrease image size Notes 1. Atul Kohli, ‘State, society and development’, in: Ira Katnelson & Helen V. Milner (eds), Political Science: The State of the Discipline (W. W. Norton & Co., 2002), p. 117. 2. Dani Rodrik, ‘Growth strategies’, in: Philippe Aghion & Ste...
LBD Double Burden of Malnutrition Collaborators, Damaris K. Kinyoki, Jennifer M. Ross, Alice Lazzar-Atwood et al.
A double burden of malnutrition occurs when individuals, household members or communities experience both undernutrition and overweight. Here, we show geospatial estimates of overweight and wasting prevalence among children under 5 years of age in 105 low- and middle-income countries (LMICs) from 20...
Jacques Izopet, Alain Labrique, Buddha Basnyat, Harry R. Dalton et al.
Background Hepatitis E causes a significant burden of disease in developing countries and has recently been increasingly recognized in developed countries. Comparing population anti-hepatitis E virus (HEV) seroprevalence across populations has been difficult. Objectives The aim of this study was to ...
Michael A. Souffront Alcantara, E. James Nelson, Kiran Shakya, Christopher Edwards et al.
Hydrologic modeling can be used to aid in decision-making at the local scale. Developed countries usually have their own hydrologic models; however, developing countries often have limited hydrologic modeling capabilities due to factors such as the maintenance, computational costs, and technical cap...
Emily Haeuser, Audrey L. Serfes, Michael A. Cork, Mingyou Yang et al.
BACKGROUND: Human immunodeficiency virus and acquired immune deficiency syndrome (HIV/AIDS) is still among the leading causes of disease burden and mortality in sub-Saharan Africa (SSA), and the world is not on track to meet targets set for ending the epidemic by the Joint United Nations Programme o...
Brittany Kmush, Alain Labrique, Harry R. Dalton, Zabed Bin Ahmed et al.
Hepatitis E virus (HEV) is a global pathogen responsible for approximately 20 million infections every year in developing countries, yet remains under-recognized. In this population-based cohort study, 1,025 randomly selected participants were enrolled from Matlab, Bangladesh (2004-2005). All partic...
Christopher D. Heaney, Brittany Kmush, Ana Navas‐Acién, Kevin A. Francesconi et al.
Background Arsenic has immunomodulatory properties and may have the potential to alter susceptibility to infection in humans. Objectives We aimed to assess the relation of arsenic exposure during pregnancy with immune function and hepatitis E virus (HEV) infection, defined as seroconversion during p...