Daniel H. Paris, Mallika Imwong, Abul Faiz, Mahtabuddin Hasan et al.
A recently described loop-mediated isothermal polymerase chain reaction (LAMP) for molecular detection of Plasmodium falciparum was compared with microscopy, PfHRP2-based rapid diagnostic test (RDT), and nested polymerase chain reaction (PCR) as the "gold standard" in 115 Bangladeshi in-patients wit...
Wiebke Albrecht, Franziska Kappenberg, Tim Brecklinghaus, Regina Stoeber et al.
Drug-induced liver injury (DILI) cannot be accurately predicted by animal models. In addition, currently available in vitro methods do not allow for the estimation of hepatotoxic doses or the determination of an acceptable daily intake (ADI). To overcome this limitation, an in vitro/in silico method...
Catherine Wilson, Timothy R. Wilson, Patrick G. Johnston, Daniel B. Longley et al.
Chemotherapy-induced interleukin-8 (IL-8) signaling reduces the sensitivity of prostate cancer cells to undergo apoptosis. In this study, we investigated how endogenous and drug-induced IL-8 signaling altered the extrinsic apoptosis pathway by determining the sensitivity of LNCaP and PC3 cells to ad...
S. Goedhart, W. D. Cotton, F. Camilo, M. A. Thompson et al.
ABSTRACT We present the SARAO MeerKAT Galactic Plane Survey (SMGPS), a 1.3 GHz continuum survey of almost half of the Galactic Plane (251° ≤l ≤ 358° and 2° ≤l ≤ 61° at |b| ≤ $1{_{.}^{\circ}}5$). SMGPS is the largest, most sensitive, and highest angular resolution 1 GHz survey of the plane yet carrie...
Abdullah H Baqui, Shams El Arifeen, Heather Rosen, Ishtiaq Mannan et al.
OBJECTIVES: To validate trained community health workers' recognition of signs and symptoms of newborn illnesses and classification of illnesses using a clinical algorithm during routine home visits in rural Bangladesh. METHODS: Between August 2005 and May 2006, 288 newborns were assessed independen...
Eric D. McCollum, Daniel E. Park, Nora L. Watson, W Chris Buck et al.
INTRODUCTION: Paediatric lung sound recordings can be systematically assessed, but methodological feasibility and validity is unknown, especially from developing countries. We examined the performance of acoustically interpreting recorded paediatric lung sounds and compared sound characteristics bet...
Ana Carolina Esteves Dias, Derek Armitage, Prateep Kumar Nayak, Shehu Latunji Akintola et al.
Small-scale fisheries (SSF) support over 90% of the 120 million people engaged in capture fisheries globally. Despite their contributions, SSF communities are often economically and politically marginalised, are highly vulnerable to change, and until recently, remained largely invisible in policy de...
Sri Charitha Koneru, Geeta Sikand, Anandita Agarwala
South Asians are at an elevated risk of atherosclerotic cardiovascular disease (ASCVD) when compared with other age-matched subjects of varied ethnicities. The elevated ASCVD risk is multifactorial including a constellation of hypertension, dyslipidemia, metabolic syndrome, overweight/obesity, predi...
Daniel E. Park, Nora L. Watson, Christopher Focht, Daniel R. Feikin et al.
Background Diagnosis of pneumonia remains challenging. Digitally recorded and remote human classified lung sounds may offer benefits beyond conventional auscultation, but it is unclear whether classifications differ between the two approaches. We evaluated concordance between digital and conventiona...
Nandita Perumal, Eric O. Ohuma, Andrew M. Prentice, Prakesh S. Shah et al.
Abstract Background The INTERGROWTH‐21st sex and gestational age (GA) specific newborn size standards (IG‐NS) are intended to complement the World Health Organization Child Growth Standards (WHO‐GS), which are not GA‐specific. We examined the implications of using IG‐NS at birth and WHO‐GS at postna...
Christine Krupa, Huma Qamar, Karen M O’Callaghan, Akpevwe Onoyovwi et al.
Vitamin D is a key regulator of bone mineral homeostasis and may modulate maternal bone health during pregnancy and postpartum. Using previously-collected data from the Maternal Vitamin D for Infant Growth (MDIG) trial in Dhaka, Bangladesh, we aimed to investigate the effects of prenatal and postpar...
Daniel Kapp, Shaun Carpenter, Angelina Ferguson, Kent Denmark et al.
Objective: To assess real-world effectiveness of Innovamatrix™, a dehydrated porcine placental extracellular matrix (PPECM), in chronic wounds refractory to 30 days of optimized standard-of-care (SOC) therapy. Methods: Multicenter retrospective analysis of 72 chronic wounds (18 diabetic foot ulcers ...
Christine Krupa, Huma Qamar, Akpevwe Onoyovwi, Abdullah Al Mahmud et al.
To estimate the dose-dependent effect of prenatal and postpartum vitamin D supplementation on circulating concentrations of biomarkers of maternal bone formation (osteoprotegerin [OPG], osteocalcin [OC], procollagen type 1 amino-terminal propeptide [P1NP], and OPG/RANKL ratio), bone resorption (rece...
Huma Qamar, Akpevwe Onoyovwi, Abdullah Al Mahmud, Tahmeed Ahmed et al.
To estimate the associations of venous cord, infant 3-month, and 6-month bone-related biomarker concentrations (amino-terminal propeptide of C-type natriuretic peptide [NT-proCNP], fibroblast-like growth factor 21 [FGF21], receptor activator of nuclear activator kappa-b ligand [RANKL], osteoproteger...
Marlee A. Tucker, Katrin Böhning‐Gaese, William F. Fagan, John M. Fryxell et al.
<b>Abstract</b><br/>Animal movement is fundamental for ecosystem functioning and species survival, yet the effects of the anthropogenic footprint on animal movements have not been estimated across species. Using a unique GPS-tracking database of 803 individuals across 57 species, w...