Bin Zhou, Rodrigo M. Carrillo‐Larco, Goodarz Danaei, Leanne M Riley et al.
BACKGROUND: Hypertension can be detected at the primary health-care level and low-cost treatments can effectively control hypertension. We aimed to measure the prevalence of hypertension and progress in its detection, treatment, and control from 1990 to 2019 for 200 countries and territories. METHOD...
Monika Böhm, Ben Collen, Jonathan Baillie, Philip Bowles et al.
Effective and targeted conservation action requires detailed information about species, their distribution, systematics and ecology as well as the distribution of threat processes which affect them. Knowledge of reptilian diversity remains surprisingly disparate, and innovative means of gaining rapi...
Honor Bixby, James Bentham, Bin Zhou, Mariachiara Di Cesare et al.
Abstract Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities 1,2 . This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity 3–6 . Here we use 2...
Marjan Walli-Attaei, Philip Joseph, Annika Rosengren, Clara K Chow et al.
BACKGROUND Some studies, mainly from high-income countries (HICs), report that women receive less care (investigations and treatments) for cardiovascular disease than do men and might have a higher risk of death. However, very few studies systematically report risk factors, use of primary or seconda...
Philomin Juliana, Jesse Poland, Julio Huerta‐Espino, Sandesh Shrestha et al.
Bread wheat improvement using genomic tools is essential for accelerating trait genetic gains. Here we report the genomic predictabilities of 35 key traits and demonstrate the potential of genomic selection for wheat end-use quality. We also performed a large genome-wide association study that ident...
Brian Godman, Abiodun Egwuenu, Mainul Haque, Oliver Ombeva Malande et al.
Antimicrobial resistance (AMR) is a high priority across countries as it increases morbidity, mortality and costs. Concerns with AMR have resulted in multiple initiatives internationally, nationally and regionally to enhance appropriate antibiotic utilization across sectors to reduce AMR, with the o...
Mercedes Herrera, Abul Bashar Mir Md. Khademul Islam, Alberto Herrera, Paloma Martín et al.
PURPOSE: Cancer-associated fibroblasts (CAF) actively participate in reciprocal communication with tumor cells and with other cell types in the microenvironment, contributing to a tumor-permissive neighborhood and promoting tumor progression. The aim of this study is the characterization of how CAFs...
Spencer L James, Chris D Castle, Zachary V Dingels, Jack T Fox et al.
BACKGROUND: While there is a long history of measuring death and disability from injuries, modern research methods must account for the wide spectrum of disability that can occur in an injury, and must provide estimates with sufficient demographic, geographical and temporal detail to be useful for p...
Juan Burgueño, José Crossa, José Miguel Cotes Torres, Félix San Vicente et al.
ABSTRACT Fixed linear models have been used for describing genotype × environment interaction (GE). Previous attempts have been made to assess the predictive ability of some linear mixed models when GE components are treated as random effects and modeled by the factor analytic (FA) model. This study...
J. Peter W. Young, Sara Moeskjær, Alexey М. Afonin, Praveen Rahi et al.
Bacteria currently included in Rhizobium leguminosarum are too diverse to be considered a single species, so we can refer to this as a species complex (the Rlc). We have found 429 publicly available genome sequences that fall within the Rlc and these show that the Rlc is a distinct entity, well sepa...
Natalie I Mazur, Yvette N. Löwensteyn, Joukje E. Willemsen, Christopher Gill et al.
BACKGROUND: Respiratory syncytial virus (RSV) is a leading cause of pediatric death, with >99% of mortality occurring in low- and lower middle-income countries. At least half of RSV-related deaths are estimated to occur in the community, but clinical characteristics of this group of children remain ...
Emily Haeuser, Audrey L. Serfes, Michael A. Cork, Mingyou Yang et al.
BACKGROUND: Human immunodeficiency virus and acquired immune deficiency syndrome (HIV/AIDS) is still among the leading causes of disease burden and mortality in sub-Saharan Africa (SSA), and the world is not on track to meet targets set for ending the epidemic by the Joint United Nations Programme o...
Ismail Mondal, SK Ariful Hossain, Sujit Kumar Roy, Jay Karmakar et al.
Hafez Ahmad, Mohammed Abdallah, Felix Jose, Hussam Eldin Elzain et al.
Juanita A. Haagsma, Periklis Charalampous, Filippo Ariani, Anne Gallay et al.
BACKGROUND: Injury remains a major concern to public health in the European region. Previous iterations of the Global Burden of Disease (GBD) study showed wide variation in injury death and disability adjusted life year (DALY) rates across Europe, indicating injury inequality gaps between sub-region...