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Results for “"Gökhan Zengin"”

16+ results

Phytol: A review of biomedical activities

Verified

Muhammad Torequl Islam, Eunüs S. Ali, Shaikh Jamal Uddin, Subrata Shaw et al.

Journal: Food and Chemical ToxicologyYear: 2018Citations: 459

Phytol (PYT) is a diterpene member of the long-chain unsaturated acyclic alcohols. PYT and some of its derivatives, including phytanic acid (PA), exert a wide range of biological effects. PYT is a valuable essential oil (EO) used as a fragrance and a potential candidate for a broad range of applicat...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Myricetin: A comprehensive review on its biological potentials

Verified

Muhammad Imran, Farhan Saeed, Ghulam Hussain, Ali Imran et al.

Journal: Food Science & NutritionYear: 2021Citations: 198

Abstract Myricetin is a critical nutritive component of diet providing immunological protection and beneficial for maintaining good health. It is found in fruits, vegetables, tea, and wine. The families Myricaceae , Polygonaceae , Primulaceae , Pinaceae, and Anacardiaceae are the richest sources of ...

Health SciencesMedicineBiochemistryOpen Access
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Pharmacological insights into the multifaceted biological properties of quinic acid

Verified

Taoufiq Benali, Saad Bakrim, Rokaia Ghchime, Nesrine Benkhaira et al.

Journal: Biotechnology and Genetic Engineering ReviewsYear: 2022Citations: 195

Quinic acid is a cyclohexanecarboxylic acid contained in the extracts of several parts of medicinal plants including Haematocarpus validus, Hypericum empetrifolium, Achillea pseudoaleppica, Rumex nepalensis, Phagnalon saxatile subsp. saxatile, Coffea arabica, Ziziphus lotus L, and Artemisia annua L ...

Health SciencesMedicineEndocrinology, Diabetes and Metabolism
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Nutraceuticals in Neurological Disorders

Verified

Rashita Makkar, Tapan Behl, Simona Bungău, Gökhan Zengin et al.

Journal: International Journal of Molecular SciencesYear: 2020Citations: 174

Neurological diseases are one of the major healthcare issues worldwide. Posed lifestyle changes are associated with drastically increased risk of chronic illness and diseases, posing a substantial healthcare and financial burden to society globally. Researchers aim to provide fine treatment for aili...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Phytochemicals from Plant Foods as Potential Source of Antiviral Agents: An Overview

Verified

Tapan Behl, Gabriele Rocchetti, Swati Chadha, Gökhan Zengin et al.

Journal: PharmaceuticalsYear: 2021Citations: 132

To date, the leading causes of mortality and morbidity worldwide include viral infections, such as Ebola, influenza virus, acquired immunodeficiency syndrome (AIDS), severe acute respiratory syndrome (SARS) and recently COVID-19 disease, caused by the SARS-CoV-2 virus. Currently, we can count on a n...

Life SciencesBiochemistry, Genetics and Molecular BiologyBiotechnologyOpen Access
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The dual impact of ACE2 in COVID-19 and ironical actions in geriatrics and pediatrics with possible therapeutic solutions

Verified

Tapan Behl, Ishnoor Kaur, Simona Bungău, Arun Kumar et al.

Journal: Life SciencesYear: 2020Citations: 105

The novel corona virus disease has shaken the entire world with its deadly effects and rapid transmission rates, posing a significant challenge to the healthcare authorities to develop suitable therapeutic solution to save lives on earth. The review aims to grab the attention of the researchers all ...

Health SciencesMedicineInfectious DiseasesOpen Access
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Comprehensive review on naringenin and naringin polyphenols as a potent anticancer agent

Verified

Abdur Rauf, Mohammad Ali Shariati, Muhammad Imran, Kashif Bashir et al.

Journal: Environmental Science and Pollution ResearchYear: 2022Citations: 103

Though the incidence of several cancers in Western societies is regulated wisely, some cancers such as breast, lung, and colorectal cancer are currently rising in many low- and middle-income countries due to increased risk factors triggered by societal and development problems. Surgery, chemotherapy...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Biology
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Therapeutic potential of herbal medicine for the management of hyperlipidemia: latest updates

Verified

Abdur Rauf, Muhammad Akram, Hina Anwar, Muhammad Daniyal et al.

Journal: Environmental Science and Pollution ResearchYear: 2022Citations: 76

Hyperlipidemia, the most common form of dyslipidemia, is the main source of cardiovascular disorders, characterized by elevated level of total cholesterol (TC), triglycerides (TG) and low-density lipoprotein cholesterol (LDL-C) with high-density lipoprotein cholesterol (HDL-C) in peripheral blood. I...

Health SciencesMedicineEndocrinology, Diabetes and Metabolism
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Dysregulation of the Gut-Brain Axis, Dysbiosis and Influence of Numerous Factors on Gut Microbiota Associated Parkinson’s Disease

Verified

Gagandeep Kaur, Tapan Behl, Simona Bungău, Arun Kumar et al.

Journal: Current NeuropharmacologyYear: 2020Citations: 56

BACKGROUND: Parkinson's disease (PD) has been one of the substantial social, medical concerns and, burdens of the present time. PD is a gradually devastating neurodegenerative disorder of the neurological function marked with α-synucleinopathy affecting numerous regions of the brain-gut axis, as wel...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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LC-MS/HRMS Analysis, Anti-Cancer, Anti-Enzymatic and Anti-Oxidant Effects of Boerhavia diffusa Extracts: A Potential Raw Material for Functional Applications

Verified

Kouadio Ibrahime Sinan, Uğur Akpulat, Afaf Aldahish, Yasemin Çelik Altunoğlu et al.

Journal: AntioxidantsYear: 2021Citations: 51

Boerhavia diffusa is a great tropical plant and is widely used for various traditional purposes. In the present study, we examined the influence of solvents (dichloromethane, ethyl acetate, methanol and infusion (water)) on chemical composition and biological capabilities of B. diffusa. An UHPLC-HRM...

Life SciencesAgricultural and Biological SciencesPlant ScienceOpen Access
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Mechanistic insights into the role of pyroptosis in rheumatoid arthritis

Verified

Swati Chadha, Tapan Behl, Simona Bungău, Arun Kumar et al.

Journal: Current Research in Translational MedicineYear: 2020Citations: 45

Cell death is ascribed as an essential biological process that is fundamental for the development of an organism along with its survival. The procedure comprises of apoptosis and pyroptosis. Pyroptosis is a programmed procedure for cell death which is inflammatory in nature and this pathway gets act...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Biology
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Integrated analysis of antimicrobial, antioxidant, and phytochemical properties of Cinnamomum verum: A comprehensive In vitro and In silico study

Verified

Samiah H. Al-Mijalli, Hanae Naceiri Mrabti, Naoufal El Hachlafi, Taha El Kamili et al.

Journal: Biochemical Systematics and EcologyYear: 2023Citations: 44
Life SciencesAgricultural and Biological SciencesPlant Science
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Antioxidant and Enzyme Inhibitory Properties, and HPLC–MS/MS Profiles of Different Extracts of Arabis carduchorum Boiss.: An Endemic Plant to Turkey

Verified

Abdullahi İbrahim Uba, Gökhan Zengin, Domenico Montesano, Uğur Çakılcıoğlu et al.

Journal: Applied SciencesYear: 2022Citations: 32

In this study, six extracts of Arabis carduchorum prepared from solvents of varying polarity (water, methanol, ethyl acetate, dichloromethane, and n-hexane) were investigated for their chemical profiles and total phenolic and flavonoid contents (TPC/TFC) using HPLC–MS/MS and spectrophotometric/color...

Health SciencesMedicineBiochemistryOpen Access
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Deciphering the Neuroprotective Role of Glucagon-like Peptide-1 Agonists in Diabetic Neuropathy: Current Perspective and Future Directions

Verified

Keshav Mehta, Tapan Behl, Arun Kumar, Md. Sahab Uddin et al.

Journal: Current Protein and Peptide ScienceYear: 2020Citations: 19

Diabetic neuropathy is referred to as a subsequential and debilitating complication belonging to type 1 and type 2 diabetes mellitus. It is a heterogeneous group of disorders with a particularly complex pathophysiology and also includes multiple forms, ranging from normal discomfort to death. The ev...

Health SciencesMedicineEndocrinology, Diabetes and Metabolism
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Molecular insights into therapeutic promise of targeting of Wnt/β-catenin signaling pathway in obesity

Verified

Priya Nijhawan, Tapan Behl, Simona Bungău, Md. Sahab Uddin et al.

Journal: Molecular Biology ReportsYear: 2020Citations: 13

Obesity is a curable disorder which is a global health concern, linked to an excess amount of fat. It is caused by inherited and environmental factors and can be grim to maintain through dieting only. The importance of peculiar Wnt/β-catenin signaling has directed considerable efforts in the future ...

Health SciencesMedicinePhysiology
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