Rebecca Sims, Sarah Dwyer, Denise Harold, Amy Gerrish et al.
We sought to investigate the contribution of extended runs of homozygosity in a genome-wide association dataset of 1,955 Alzheimer's disease cases and 955 elderly screened controls genotyped for 529,205 autosomal single nucleotide polymorphisms. Tracts of homozygosity may mark regions inherited from...
Akanksha A. Marphatia, Sheillah Simiyu, MJ O'Kane, Kelly Alexander et al.
Summary box Sanitation is critical to improving quality of life and gender equality.
Janet Johnston, Malene Jensen, Lars Lannfelt, Brian Walker et al.
Abeta peptides are major components of the amyloid plaques that characterize Alzheimer's disease. The enzyme activities (beta- and gamma-secretases) involved in generating Abeta from amyloid precursor protein (APP) are unidentified. It has been suggested that prolylendopeptidase (PEP), an oligopepti...
B. M. Ryan, Susan McKiernan, P. W. N. Keeling, P. J. Byrne et al.