Mainul Haque, Judy McKimm, Massimo Sartelli, Sameer Dhingra et al.
Healthcare-associated infections (HCAIs) are a major source of morbidity and mortality and are the second most prevalent cause of death. Furthermore, it has been reported that for every one-hundred patients admitted to hospital, seven patients in high-income economies and ten in emerging and low-inc...
Natalia V. Bhattacharjee, Lauren E. Schaeffer, Simon I Hay, Local Burden of Disease Exclusive Breastfeeding Collaborators et al.
Exclusive breastfeeding (EBF)-giving infants only breast-milk for the first 6 months of life-is a component of optimal breastfeeding practices effective in preventing child morbidity and mortality. EBF practices are known to vary by population and comparable subnational estimates of prevalence and p...
Rimple Jeet Kaur, Siddhartha Dutta, Jaykaran Charan, Pankaj Bhardwaj et al.
Background: Thirteen COVID-19 vaccines are granted emergency approval. It is crucial to monitor their adverse events post vaccination. The present study focuses on cardiovascular adverse events post-COVID-19 vaccination and aims to determine adverse events with the administered vaccine. Methodology:...
Brian Godman, Mainul Haque, Salequl Islam, Samiul Iqbal et al.
Background: Countries have introduced a variety of measures to prevent and treat COVID-19 with medicines and personal protective equipment (PPE), with some countries adopting preventative strategies earlier than others. However, there has been considerable controversy surrounding some treatments. Th...
Shahad Saif Khandker, Brian Godman, Md. Irfan Jawad, Bushra Ayat Meghla et al.
COVID-19 vaccines are indispensable, with the number of cases and mortality still rising, and currently no medicines are routinely available for reducing morbidity and mortality, apart from dexamethasone, although others are being trialed and launched. To date, only a limited number of vaccines have...
Rimple Jeet Kaur, Jaykaran Charan, Siddhartha Dutta, Paras Sharma et al.
BACKGROUND: COVID-19 caused by SARS-CoV-2 virus emerged as an unprecedented challenge to discover effective drugs for its prevention and cure. Hyperinflammation-induced lung damage is one of the poor prognostic indicators causing a higher rate of morbidity and mortality of COVID-19 patients. Favipir...
Mainul Haque, Santosh Kumar, Jaykaran Charan, Rohan Bhatt et al.
Background: COVID-19 has already claimed a considerable number of lives worldwide. However, there are concerns with treatment recommendations given the extent of conflicting results with suggested treatments and misinformation, some of which has resulted in increased prices and shortages alongside i...
Emily Haeuser, Audrey L. Serfes, Michael A. Cork, Mingyou Yang et al.
BACKGROUND: Human immunodeficiency virus and acquired immune deficiency syndrome (HIV/AIDS) is still among the leading causes of disease burden and mortality in sub-Saharan Africa (SSA), and the world is not on track to meet targets set for ending the epidemic by the Joint United Nations Programme o...
Mainul Haque, Salequl Islam, Md. Arif Sheikh, Sameer Dhingra et al.
INTRODUCTION: Quorum-sensing (QS) is a microbial cell-to-cell communication system that utilizes small signaling molecules to mediates interactions between cross-kingdom microorganisms, including Gram-positive and -negative microbes. QS molecules include N-acyl-homoserine-lactones (AHLs), furanosyl ...
Jaykaran Charan, Siddhartha Dutta, Rimple Jeet Kaur, Pankaj Bhardwaj et al.
BACKGROUND: Elevated inflammatory cytokines in Coronavirus disease 2019 (COVID-19) affect the lungs leading to pneumonitis with a poor prognosis. Tocilizumab, a type of humanized monoclonal antibody antagonizing interleukin-6 receptors, is currently utilized to treat COVID-19. The present study revi...
Sayeeda Rahman, Keerti Singh, Sameer Dhingra, Jaykaran Charan et al.
COVID-19 pandemic is inducing acute respiratory distress syndrome, multi-organ failure, and eventual death. Respiratory failure is the leading cause of mortality in the elderly population with pre-existing medical conditions. This group is particularly vulnerable to infections due to a declined immu...
Brian Godman, Mainul Haque, Trudy Leong, Eleonora Allocati et al.
Background: Diabetes mellitus rates continue to rise, which coupled with increasing costs of associated complications has appreciably increased global expenditure in recent years. The risk of complications are enhanced by poor glycaemic control including hypoglycaemia. Long-acting insulin analogues ...
Nandeeta Samad, Siddhartha Dutta, Temitayo Eniola Sodunke, Adiba Fairuz et al.
The outbreak of pneumonia caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), later named COVID-19 by the World Health Organization (WHO), was initiated at Wuhan, Hubei, China, and there was a rapid spread of novel SARS-CoV-2 and the disease COVID-19 in late 2019. The entire worl...
Brian Godman, Mainul Haque, Santosh Kumar, Salequl Islam et al.
INTRODUCTION: Prevalence rates for diabetes mellitus continue to rise, which, coupled with increasing costs of complications, has appreciably increased expenditure in recent years. Poor glycaemic control including hypoglycaemia enhances complication rates and associated morbidity, mortality and cost...
Siddhartha Dutta, Sayeeda Rahman, Rahnuma Ahmad, Tarun Kumar et al.
INTRODUCTION: Dementia is a progressive neurodegenerative disorder impairing memory and cognition. Alzheimer's Disease, followed by vascular dementia - the most typical form. Risk factors for vascular dementia include diabetes, cardiovascular disease, hyperlipidemia. Lipids' levels are significantly...