Susan Walker, Theodore D. Wachs, Sally Grantham‐McGregor, Maureen M. Black et al.
Inequality between and within populations has origins in adverse early experiences. Developmental neuroscience shows how early biological and psychosocial experiences affect brain development. We previously identified inadequate cognitive stimulation, stunting, iodine deficiency, and iron-deficiency...
R. Bhopal, Nigel Unwin, Martin White, Julie Yallop et al.
OBJECTIVE: To compare coronary risk factors and disease prevalence among Indians, Pakistanis, and Bangladeshis, and in all South Asians (these three groups together) with Europeans. DESIGN: Cross sectional survey. SETTING: Newcastle upon Tyne. PARTICIPANTS: 259 Indian, 305 Pakistani, 120 Bangladeshi...
Dennis Egger, Edward Miguel, Shana S. Warren, Ashish Shenoy et al.
Despite numerous journalistic accounts, systematic quantitative evidence on economic conditions during the ongoing COVID-19 pandemic remains scarce for most low- and middle-income countries, partly due to limitations of official economic statistics in environments with large informal sectors and sub...
Eileen E. Parkes, Steven M. Walker, Laura E. Taggart, Nuala McCabe et al.
Background: Previously we identified a DNA damage response-deficient (DDRD) molecular subtype within breast cancer. A 44-gene assay identifying this subtype was validated as predicting benefit from DNA-damaging chemotherapy. This subtype was defined by interferon signaling. In this study, we address...
Mihai Pop, Alan W. Walker, Joseph N. Paulson, Brianna Lindsay et al.
BACKGROUND: Diarrheal diseases continue to contribute significantly to morbidity and mortality in infants and young children in developing countries. There is an urgent need to better understand the contributions of novel, potentially uncultured, diarrheal pathogens to severe diarrheal disease, as w...
Frederick Koster, Jack Levin, L Walker, Kenneth S. K. Tung et al.
To investigate three possible causes of the acute hemolysis in the hemolytic-uremic syndrome, we studied prospectively 207 children and 34 adults with shigellosis in Bangladesh. Nineteen children showed acute hemolytic anemia, a leukemoid reaction, thrombocytopenia and oliguria; nine other had, in a...
José Martines, Vinod K. Paul, Zulfiqar A Bhutta, Marjorie A. Koblinsky et al.
To achieve the Millennium Development Goal for child survival (MDG-4), neonatal deaths need to be prevented. Previous papers in this series have presented the size of the problem, discussed cost-effective interventions, and outlined a systematic approach to overcoming health-system constraints to sc...
S Campbell, Marion Campbell, Jeremy Grimshaw, Alison Walker
BACKGROUND: The aim of the study was to review systematically the literature measuring the accuracy of routine UK hospital statistics that classify patients on discharge. METHODS: A systematic review was carried out of studies comparing routine discharge statistics about an episode of hospital care ...
Adrian Grant, D. G. Altman, Abdel Babiker, Marion Campbell et al.
OBJECTIVES: To address issues about data monitoring committees (DMCs) for randomised controlled trials (RCTs). DATA SOURCES: Electronic databases. Handsearching of selected books. Personal contacts with experts in the field. REVIEW METHODS: Systematic literature reviews of DMCs and small group proce...
Jack Stone, Hannah Fraser, Aaron G. Lim, Josephine G. Walker et al.
BACKGROUND: People who inject drugs (PWID) experience a high prevalence of incarceration and might be at high risk of HIV and hepatitis C virus (HCV) infection during or after incarceration. We aimed to assess whether incarceration history elevates HIV or HCV acquisition risk among PWID. METHODS: st...
Melanie‐Jayne R. Howes, Cassandra L. Quave, Jérôme Collemare, Evangelos C. Tatsis et al.
Societal Impact Statement Plants and fungi have provided, or inspired, key pharmaceuticals for global health challenges, including cancer, heart disease, dementia, and malaria, and are valued as traditional medicines worldwide. Global demand for medicinal plants and fungi has threatened certain spec...
Rabiul Islam, Greg Walkerden
Shi Wu Wen, Xi-Kuan Chen, Marc Rodger, Ruth Rennicks White et al.
Objective The objective of the study was to evaluate the association between folic acid supplementation in early second trimester and the risk of developing preeclampsia. Study design We carried out a prospective cohort study between October 2002-December 2005. We recruited women who had their prena...
Neal Russell, Wolfgang Stöhr, Nishad Plakkal, Aislinn Cook et al.
BACKGROUND: There is limited data on antibiotic treatment in hospitalized neonates in low- and middle-income countries (LMICs). We aimed to describe patterns of antibiotic use, pathogens, and clinical outcomes, and to develop a severity score predicting mortality in neonatal sepsis to inform future ...
Pietro Nenoff, Shyam B. Verma, Andreas Ebert, Anke Süß et al.
Chronic recalcitrant dermatophytoses, due to Trichophyton (T.) mentagrophytes Type VIII are on the rise in India and are noteworthy for their predominance. It would not be wrong to assume that travel and migration would be responsible for the spread of T. mentagrophytes Type VIII from India, with ma...