M. John Albert, Abdullah Siddique, M. Sirajul Islam, Abu Syed Golam Faruque et al.
John D. Clemens, David A. Sack, Jeffrey R. Harris, J. Chakraborty et al.
The B subunit (BS) of cholera toxin and that of the heat-labile enterotoxin (LT) of enterotoxigenic Escherichia coli (ETEC) are antigenically similar. We therefore assessed whether a combined cholera toxin BS/whole-cell (BS-WC) oral vaccine against cholera conferred cross-protection against LT-produ...
Marcelino Lucas, Jacqueline Deen, Lorenz von Seidlein, Xuan-Yi Wang et al.
BACKGROUND: New-generation, orally administered cholera vaccines offer the promise of improved control of cholera in sub-Saharan Africa. However, the high prevalence of human immunodeficiency virus (HIV) infection in many cholera-affected African populations has raised doubts about the level of prot...
M. JOHN ALBERT, M. Ansaruzzaman, Kaisar A. Talukder, Ashok K. Chopra et al.
Aeromonads are causative agents of a number of human infections. Even though aeromonads have been isolated from patients suffering from diarrhea, their etiological role in gastroenteritis is unclear. In spite of a number of virulence factors produced by Aeromonas species, their association with diar...
M. John Albert, Shah M. Faruque, Abu Syed Golam Faruque, P K Neogi et al.
Diarrheal diseases are highly prevalent in Bangladesh. However, the relative contribution of diarrheagenic Escherichia coli organisms--those that are enterotoxigenic (ETEC), enteropathogenic (EPEC), enteroinvasive, enterohemorrhagic, enteroaggregative, and diffuse adherent--to diarrhea in Bangladesh...
M. Ansaruzzaman, N. A. Bhuiyan, G. Balakrish Nair, David A. Sack et al.
To the Editor: Cholera outbreaks caused by toxigenic Vibrio cholerae serogroup O1 frequently occur in many sub-Saharan African countries. The serogroup O1 is classified into two biotypes, classical and El Tor. The seventh and current pandemic of cholera is caused by the El Tor biotype; the classical...
M. John Albert, Shah M. Faruque, M. Ansaruzzaman, Moydul Islam et al.
Seven strains of Hafnia alvei isolated from diarrhoeal stools of children resembled enteropathogenic Escherichia coli (EPEC) in that they produced attaching-effacing (AE) lesions in rabbit ileal loops and fluorescent actin staining in infected HEp-2 cells. In addition, a DNA probe from a chromosomal...
Ingolf Kühn, M. John Albert, M. Ansaruzzaman, N. A. Bhuiyan et al.
Aeromonas isolates from patients with diarrhea in Bangladesh (n = 69), from healthy controls (n = 11), and from surface water (n = 40) were analyzed with respect to their hybridization groups (HGs) by the aid of fatty acid methyl ester (FAME) characterization and DNA fingerprinting by AFLP, biochemi...
Binh Minh Nguyen, Jehee Lee, Ngo Tuan Cuong, Seon Young Choi et al.
Vibrio cholerae O1 isolates collected during cholera outbreaks occurring from late 2007 to early 2008 in northern Vietnam were revealed to represent an altered strain containing the RS1 element followed by a CTX prophage harboring El Tor type rstR and classical ctxB on the large chromosome.
M. Ansaruzzaman, Marcelino Lucas, Jacqueline Deen, N. A. Bhuiyan et al.
Forty-two episodes of Vibrio parahaemolyticus infections were detected in Beira, Mozambique, from January to May 2004. The majority of the isolates (81%) belonged to the pandemic serovars (O3:K6 and O4:K68) of V. parahaemolyticus. The pandemic serovars were positive by group-specific PCR (GS-PCR) an...
N. A. Bhuiyan, M. Ansaruzzaman, Muhammad Kamruzzaman, Khorshed Alam et al.
Sixty-six strains of Vibrio parahaemolyticus belonging to 14 serotypes were isolated from hospitalized patients in Dhaka, Bangladesh, from January 1998 to December 2000. Among these, 48 strains belonging to four serotypes had the pandemic genotype and possessed the tdh gene. A marker (open reading f...
John D. Clemens, David A. Sack, Jeffrey R. Harris, M. R. Khan et al.
Journal Article BREAST FEEDING AND THE RISK OF SEVERE CHOLERA IN RURAL BANGLADESHI CHILDREN Get access JOHN D. CLEMENS, JOHN D. CLEMENS 1International Centre for Diarrhoeal Disease ResearchBangladesh, Dhaka, Bangladesh2Center for Vaccine Development, University of Maryland School of MedicineBaltimor...
M. John Albert, Khorshed Alam, M. Ansaruzzaman, Moydul Islam et al.
Providencia alcalifaciens is a member of the family Enterobacteriaceae. There are reports that P. alcalifaciens can cause diarrhea, but the mechanism(s) by which it causes diarrhea is known. We studied P. alcalifaciens isolated from a child and two adults with diarrhea for enteropathogenicity. The t...
Jehee Lee, Kyung Ho Han, Seon Young Choi, Marcelino Lucas et al.
Vibrio cholerae O1 isolates belonging to the Ogawa serotype, El Tor biotype, harbouring the classical CTX prophage were first isolated in Mozambique in 2004. Multilocus sequence typing (MLST) analysis using nine genetic loci showed that the Mozambique isolates have the same sequence type (ST) as O1 ...
James Mwansa, John Mwaba, Chileshe Lukwesa, N. A. Bhuiyan et al.
Antibiotic resistance data, made available from laboratory records during eight cholera outbreaks between 1990 and 2004 showed Vibrio cholerae serogroup O1 to have a low level of resistance (2-3%) to tetracycline during 1990-1991. Resistance increased for tetracycline (95%), chloramphenicol (78%), d...