Alexandre F. Aissa, Abul Bashar Mir Md. Khademul Islam, Majd Ariss, Cammille C. Go et al.
Tyrosine kinase inhibitors were found to be clinically effective for treatment of patients with certain subsets of cancers carrying somatic mutations in receptor tyrosine kinases. However, the duration of clinical response is often limited, and patients ultimately develop drug resistance. Here, we u...
Lorenzo de la Rica, Javier Rodríguez‐Ubreva, Mireia García, Abul Bashar Mir Md. Khademul Islam et al.
BACKGROUND: DNA methylation is a key epigenetic mechanism for driving and stabilizing cell-fate decisions. Local deposition and removal of DNA methylation are tightly coupled with transcription factor binding, although the relationship varies with the specific differentiation process. Conversion of ...
Mercedes Herrera, Abul Bashar Mir Md. Khademul Islam, Alberto Herrera, Paloma Martín et al.
PURPOSE: Cancer-associated fibroblasts (CAF) actively participate in reciprocal communication with tumor cells and with other cell types in the microenvironment, contributing to a tumor-permissive neighborhood and promoting tumor progression. The aim of this study is the characterization of how CAFs...
Md. Abdullah‐Al‐Kamran Khan, Md. Rabi Us Sany, Md. Shafiqul Islam, Abul Bashar Mir Md. Khademul Islam
Detailed molecular mechanism of SARS-CoV-2 pathogenesis is still elusive to address its deadlier nature and to design effective theraputics. Here, we present our study elucidating the interplay between the SARS-CoV and SARS-CoV-2 viruses’; and host’s miRNAs, an epigenetic regulator, as a mode of pat...
Leonor Gama-Norton, Eva Ferrando, Cristina Ruiz‐Herguido, Zhenyi Liu et al.
Acquisition of the arterial and haemogenic endothelium fates concurrently occur in the aorta-gonad-mesonephros (AGM) region prior to haematopoietic stem cell (HSC) generation. The arterial programme depends on Dll4 and the haemogenic endothelium/HSC on Jag1-mediated Notch1 signalling. How Notch1 dis...
Lorenzo de la Rica, José Urquiza, David Gómez-Cabrero, Abul Bashar Mir Md. Khademul Islam et al.
Autoimmune rheumatic diseases are complex disorders, whose etiopathology is attributed to a crosstalk between genetic predisposition and environmental factors. Both variants of autoimmune susceptibility genes and environment are involved in the generation of aberrant epigenetic profiles in a cell-sp...
Chiara Di Vona, Daniela Bezdan, Abul Bashar Mir Md. Khademul Islam, Eulàlia Salichs et al.
DYRK1A is a dosage-sensitive protein kinase that fulfills key roles during development and in tissue homeostasis, and its dysregulation results in human pathologies. DYRK1A is present in both the nucleus and cytoplasm of mammalian cells, although its nuclear function remains unclear. Genome-wide ana...
Md. Bokhtiar Hasan, Masnun Mahi, M. Kabir Hassan, Abul Bashar Bhuiyan
We empirically explore the effect of the COVID-19 pandemic on Islamic and conventional stock markets from a global perspective. We also explore the co-movement between Islamic and conventional stock markets. Two comparable pairs of conventional and Islamic stock indices – Dow Jones Index and FTSE In...
Abul Bashar Mir Md. Khademul Islam, Md. Abdullah‐Al‐Kamran Khan
An incomplete understanding of the molecular mechanisms behind impairment of lung pathobiology by COVID-19 complicates its clinical management. In this study, we analyzed the gene expression pattern of cells obtained from biopsies of COVID-19-affected patient and compared to the effects observed in ...
Md. Ferdous Rahman, Md. Azizur Rahman, Md. Rasidul Islam, Avijit Ghosh et al.
Recently, inorganic perovskite materials have been attracting increasing attention owing to their exceptional structural, electronic, and optical characteristics in photovoltaic technology. Ca3AsI3 is a semiconductor material that shares similarities with the group of inorganic metal halide perovski...
Nazrul Islam Mondal, Kamal Hossain, Md. Rafiqul Islam, Abul Bashar Mian
We analyzed the sexual behavior and sexually transmitted diseases (STDs) of street-based female sex workers (SFSWs) of Rajshahi city and examined their socio-demographic profiles. Among the SFSWs attending three drop-in centers (DIC) named PIACT, PROVA, and Suraksha Madhumita in Rajshahi, 150 self-m...
Renáta Váraljai, Abul Bashar Mir Md. Khademul Islam, Michael L. Beshiri, Jalees Rehman et al.
The retinoblastoma tumor suppressor protein pRb restricts cell growth through inhibition of cell cycle progression. Increasing evidence suggests that pRb also promotes differentiation, but the mechanisms are poorly understood, and the key question remains as to how differentiation in tumor cells can...
Pablo Gómez‐del Arco, Eusebio Perdiguero, Paula Sofía Yunes-Leites, Rebeca Acín‐Pérez et al.
Heart muscle maintains blood circulation, while skeletal muscle powers skeletal movement. Despite having similar myofibrilar sarcomeric structures, these striated muscles differentially express specific sarcomere components to meet their distinct contractile requirements. The mechanism responsible i...
Kelly Thornber, Abul Bashar, Md. Salahuddin Ahmed, Ashley Bell et al.
Food production environments in low- and middle-income countries (LMICs) are recognized as posing significant and increasing risks to antimicrobial resistance (AMR), one of the greatest threats to global public health and food security systems. In order to maximize and expedite action in mitigating ...
Dipesh Chandra, Md. Tamzid Hossain Molla, Md Abul Bashar, Md. Suman Islam et al.
Abstract In contemplation of treating hazardous industrial wastewater, sodium tripolyphosphate (TPP) and vanillin (V)-modified chitosan-based magnetic nano-sorbents (TPP-CMN and V-CMN) were prepared, and the physical and surface properties of both nano-sorbents were characterised. The results of FE-...