Mahmuda Begum, Mayank Choubey, Munichandra Babu Tirumalasetty, Shahida Arbee et al.
Diabetes mellitus, a chronic metabolic disorder characterized by hyperglycemia, presents a formidable global health challenge with its associated complications. Adiponectin, an adipocyte-derived hormone, has emerged as a significant player in glucose metabolism and insulin sensitivity. Beyond its me...
Mahmuda Begum, Mayank Choubey, Munichandra Babu Tirumalasetty, Mohammad Mohabbulla Mohib et al.
Diabetes mellitus, a chronic metabolic disorder characterized by hyperglycemia, presents a formidable global health challenge with its associated complications. Adiponectin, an adipocyte-derived hormone, has emerged as a significant player in glucose metabolism and insulin sensitivity. Beyond its me...
Tanzir Rafe, Parvez Ahmed Shawon, Liyad Salem, Nafij Imtiyaj Chowdhury et al.
BACKGROUND: Immunity is the ultimate barrier between foreign stimuli and a host cell. Unwanted immune responses can threaten the host cells and may eventually damage a vital organ. Overproduction of inflammatory cytokines may also lead to autoimmune diseases. Inflammatory cells and pro-inflammatory ...
Mohammad Mohabbulla Mohib, S.M. Fazla Rabby, Tasfiq Zaman Paran, Md. Mehedee Hasan et al.
Nowadays, diabetes and diabetes-mediated dysfunctions are overwhelming at every nook and corner of the world which has been a sober concern to the current health care professionals. However, chronic hyperglycemic subjects often suffer from hypertension, atherosclerosis, insulin resistance, brain inj...
Humaira Binte Noor, Nusrat A. Mou, Liyad Salem, Md F.A. Shimul et al.
BACKGROUND: One of the many debated topics in inflammation research is whether this scenario is really an accelerated form of human wound healing and immunityboosting or a push towards autoimmune diseases. The answer requires a better understanding of the normal inflammatory process, including the m...
Parisha Alam, Marzeea Ahmad Raka, Salma Khan, Juthika Sarker et al.
Evidence suggests that obesity can contribute to the development of certain complications such as insulin resistance, dyslipidemia, accumulation of visceral fats and cardiovascular dysfunctions. Excess fat also blocks small blood vessels and arteries by accumulating plaque, which increases vascular ...
Mohammad Mohabbulla Mohib, Kazi Afnan, Tasfiq Zaman Paran, Salma Khan et al.
Alcoholic liver diseases and virus-induced hepatic dysfunctions are prevalent in western countries. Evidence also suggests that hyperglycemia and insulin resistance are key players in the development of hepatic diseases and their complications. Since the comorbid diseases like obesity, diabetes and ...
Mohammad Sarif Mohiuddin, Noushin Tabassum Neha, Jawad Ul Karim Mahir, Fardin Al Fahad Shakib et al.
Metabolic dysfunction-associated steatotic liver disease (MASLD), previously known as non-alcoholic fatty liver disease (NAFLD), has recently been recognized as a public health issue because it is closely linked to metabolic disorders, including type 2 diabetes mellitus (T2DM). This review aims to d...
Shamima Akter, Sadia Tasnim, Rashu Barua, Mayank Choubey et al.
The COVID-19 pandemic caused by the SARS-CoV-2 virus has led to significant global health implications. Although the respiratory manifestations of COVID-19 are widely recognized, emerging evidence suggests that the disease may also significantly affect the gut microbiota, the intricate community of ...
Shamima Akter, Mayank Choubey, Shahida Arbee, Mohammad Mohabbulla Mohib et al.
Erectile dysfunction (ED) is the inability to achieve or maintain an erection during sexual performance. ED is one of the most common and neglected complications of diabetes. Almost 35-75% of diabetic men around the world suffer from ED. Although the exact mechanism by which diabetes causes ED is no...
Shakila Jahan Shimu, Jawad Ul Karim Mahir, Fardin Al Fahad Shakib, Arafath Amin Ridoy et al.
Obesity-induced insulin resistance and type 2 diabetes mellitus (T2DM) represent complex systemic disorders marked by chronic inflammation, oxidative stress, mitochondrial dysfunction, and endoplasmic reticulum (ER) stress. These pathophysiological processes disrupt insulin signaling and β-cell func...
Nafees Uddin Chowdhury, Abida Tisha, Juthika Sarker, Pulak Dev Nath et al.
Vascular damage and subsequent cardiac failure due to immune cytokines is steadily increasing the morbidity of cardiovascular diseases (CVD), making them the leading cause of death globally. Nevertheless, improper diagnosis is an important hurdle in case management. Free radicals are one of major fa...
Marzeea Ahmad Raka, Abida Tisha, Salma Khan, Tasfiq Zaman Paran et al.
Background: Chronic and non-communicable diseases such as non-alcoholic fatty liver diseases, non-alcoholic steatohepatitis, obesity, diabetes, cardiovascular dysfunctions, renal insufficiency, alcoholism and other inflammation disorders often lead to severe organ damage. Fibrosis, on the contrary, ...
Shakila Jahan Shimu, Shamima Akter, Marzia Rahman, Shahida Arbee et al.
Background: Diabetes and mental health conditions frequently co-occur, with depression and anxiety affecting up to 20–30% of people with diabetes. These comorbidities worsen glycemic control, adherence, and quality of life, yet mental health is often neglected in diabetes care. Integrating mental he...
Shamima Akter, Mayank Choubey, Shahida Arbee, Mohammad Mohabbulla Mohib et al.
Cardiovascular disease (CVD), comprising heart and blood vessel disorders, persists as the foremost contributor to global morbidity and mortality. In modern times, the intricate composition of gut microbiota has garnered significant focus, particularly for its varying impact on diverse ailments. Per...
Shamima Akter, Sadia Tasnim, Rashu Barua, Mayank Choubey et al.
The COVID-19 pandemic caused by the SARS-CoV-2 virus has led to significant global health implications. Although the respiratory manifestations of COVID-19 are widely recognized, emerging evidence suggests that the disease may also significantly affect the gut microbiota, the intricate community of ...
Muhammad A.T. Sagor, Mohammad Mohabbulla Mohib, Muhammad S. Azam, Anisur Rahman et al.
Background: Angiotensin and its precursor’s peptides contribute to multiple biological functions and regulate several important mechanisms like hormone production, fluid balance, growth, and apoptosis throughout the body. The function of Ang-II is generally mediated through AT1R and AT2R which monit...
Shamima Akter, Mayank Choubey, Md. Mokhlesur Rahman, Shahida Arbee et al.
Cardiovascular disease (CVD), comprising heart and blood vessel disorders, persists as the foremost contributor to global morbidity and mortality. In modern times, the intricate composition of gut microbiota has garnered significant focus, particularly for its varying impact on diverse ailments. Gut...
Mohammad Mohabbulla Mohib, Mohammad Borhan Uddin, Md. Mokhlesur Rahman, Munichandra Babu Tirumalasetty et al.
Background: Schizophrenia is a complex neuropsychiatric disorder whose pathophysiology may involve oxidative stress-induced neuronal damage and inflammation. We conducted a cross-species study to elucidate oxidative stress dysregulation in schizophrenia. Methods: We measured peripheral oxidative str...