Md. Mahbubor Rahman, Md. Badrul Islam, Mohitosh Biswas, Aftab Alam
BACKGROUND: In humans, many diseases are associated with the accumulation of free radicals. Antioxidants can scavenge free radicals and minimize their impact. Therefore, the search for naturally occurring antioxidants of plant origin is imperative. Here, we aimed to investigate the antioxidant and f...
Mohitosh Biswas, Shawonur Rahaman, Tapash Kumar Biswas, Zahirul Haque et al.
<b><i>Introduction:</i></b> Although severe acute respiratory syndrome coronavirus-2 infection is causing mortality in considerable proportion of coronavirus disease-2019 (COVID-19) patients, however, evidence for the association of sex, age, and comorbidities on the risk of ...
Debendra Nath Roy, Mohitosh Biswas, Md. Ekramul Islam, Md. Shah Azam
BACKGROUND AND AIMS: Although vaccines are considered the most effective and fundamental therapeutic tools for consistently preventing the COVID-19 disease, worldwide vaccine hesitancy has become a widespread public health issue for successful immunization. The aim of this review was to identify an ...
Mohitosh Biswas, Manobendro Nath Roy, Md. Imran Nur Manik, Md Shahid Hossain et al.
BACKGROUND: Antibiotic self medication is highly prevalent in the developing countries due to easy availability and poor regulatory controls for selling these drugs. The purpose of this study was to evaluate the prevalence of self-medication with antibiotics for the treatment of various diseases by ...
Chiraphat Kloypan, Napatrupron Koomdee, Patompong Satapornpong, Therdpong Tempark et al.
Human leukocyte antigen (HLA) encoded by the HLA gene is an important modulator for immune responses and drug hypersensitivity reactions as well. Genetic polymorphisms of HLA vary widely at population level and are responsible for developing severe cutaneous adverse drug reactions (SCARs) such as St...
Mohitosh Biswas, Debendra Roy, Afsana Tajmim, Sheikh Shahriar Rajib et al.
BACKGROUND: Antibiotics prescribing by physicians have gained due importance across the globe, mainly because of an increase in antibiotic usage, prevalence of infections and drug resistances. The present study is aimed to evaluate the physicians prescribing pattern of antibiotics, their usages by o...
Mohitosh Biswas, Most. Sumaiya Khatun Kali, Tapash Kumar Biswas, Baharudin Ibrahim
The most effective antiplatelet treatments for acute coronary syndrome (ACS) patients carrying CYP2C19 loss-of-function (LoF) alleles undergoing percutaneous coronary intervention (PCI) is still debating and conflicting. It was aimed to compare the efficacy and safety endpoints for these patients tr...
Hajera Khatun, Md. Ajijur Rahman, Mohitosh Biswas, Anwar Ul Islam
This study was done to investigate the effects of water-soluble fraction (WSF) of the fruits of Abelmoschus esculentus L (okra/lady's fingers) on absorption of oral glucose as well as metformin from the gastrointestinal tract in the Long Evans rats. WSF of A. esculentus significantly (P < 0.05) redu...
Mohitosh Biswas
Genetic variability of CYP2C19 may affect safety or efficacy of many clinically important medications as outlined in the clinical pharmacogenetics implementation consortium (CPIC) dosing guidelines. To determine the predictive prevalence of high-risk phenotypes due to CYP2C19 genetic variants collec...
Mohitosh Biswas, Pimonpan Jinda, Chonlaphat Sukasem
Introduction Various pharmacogenomic (PGx) variants differ widely in different ethnicities. and clinical outcomes associated with these variants may also be substantially varied. Literature was searched in different databases, i.e. PubMed, ScienceDirect, Web of Science, and PharmGKB, from inception ...
Mohitosh Biswas, Nares Sawajan, Thanyada Rungrotmongkol, Kamonpan Sanachai et al.
Many drugs are being administered to tackle coronavirus disease 2019 (COVID-19) pandemic situations without establishing clinical effectiveness or tailoring safety. A repurposing strategy might be more effective and successful if pharmacogenetic interventions are being considered in future clinical ...
Mohitosh Biswas, Most. Sumaiya Khatun Kali
Purpose It was aimed to determine the aggregated risk of MACE (major adverse cardiovascular events) in stable CAD patients carrying CYP2C19 LoF alleles taking clopidogrel. Methods Literature was searched in different databases for relevant studies. Aggregated risk was estimated using a fixed/random ...
Mohitosh Biswas, Maliheh Ershadian, Shobana John, Ai‐Hoc Nguyen et al.
Aggregated risk of carbamazepine (CBZ)-induced cutaneous adverse drug reactions (cADRs) with different HLA variants are unclear and limited in terms of the power of studies. This study aimed to assess the aggregated risk of CBZ-induced cADRs associated with carrying the following HLA variants: HLA-B...
Mohitosh Biswas, Chonlaphat Sukasem, Most. Sumaiya Khatun Kali, Baharudin Ibrahim
LoF alleles, who underwent PCI and were treated with clopidogrel were correlated with significantly increased risk of MACE compared with noncarriers.
Mohitosh Biswas, Shawonur Rahaman, Tapash Kumar Biswas, Baharudin Ibrahim
Background Efficacy of clopidogrel may be diminished due to either co-administration of proton pump inhibitors or carrying CYP2C19 loss-of-function alleles. However, patients may be at greater risk of major adverse cardiovascular events if taking clopidogrel together with proton pump inhibitors and ...