Md. Abdus Salam, Md. Yusuf Al-Amin, Moushumi Tabassoom Salam, Jogendra Singh Pawar et al.
Antibiotics are among the most important discoveries of the 20th century, having saved millions of lives from infectious diseases. Microbes have developed acquired antimicrobial resistance (AMR) to many drugs due to high selection pressure from increasing use and misuse of antibiotics over the years...
Karine Brudey, Jeffrey Driscoll, Leen Rigouts, Wolfgang M. Prodinger et al.
BACKGROUND: The Direct Repeat locus of the Mycobacterium tuberculosis complex (MTC) is a member of the CRISPR (Clustered regularly interspaced short palindromic repeats) sequences family. Spoligotyping is the widely used PCR-based reverse-hybridization blotting technique that assays the genetic dive...
Gretchen A Stevens, Gitanjali M Singh, Yuan Lu, Goodarz Danaei et al.
BACKGROUND: Overweight and obesity prevalence are commonly used for public and policy communication of the extent of the obesity epidemic, yet comparable estimates of trends in overweight and obesity prevalence by country are not available. METHODS: We estimated trends between 1980 and 2008 in overw...
Shiv Kumar Sarin, Ashok Choudhury, Manoj K. Sharma, Rakhi Maiwall et al.
The first consensus report of the working party of the Asian Pacific Association for the Study of the Liver (APASL) set up in 2004 on acute-on-chronic liver failure (ACLF) was published in 2009. With international groups volunteering to join, the “APASL ACLF Research Consortium (AARC)” was formed in...
Ryan F. Donnelly, Thakur Raghu Raj Singh, Martin J. Garland, Katarzyna Migalska et al.
Unique microneedle arrays prepared from crosslinked polymers, which contain no drug themselves, are described. They rapidly take up skin interstitial fluid upon skin insertion to form continuous, unblockable, hydrogel conduits from attached patch-type drug reservoirs to the dermal microcirculation. ...
Rupa Chakraborty, Anupama Asthana, Ajaya Kumar Singh, Bhawana Jain et al.
Environmental pollution, particularly from heavy metal ions in the wastewater, is one of the most serious concerns of the world. In the pursuit of remedial action, various conventional methods such as ion exchange, chemical precipitation, coagulation, membrane separation, reverse osmosis, and adsorp...
J. K. Ladha, David Dawe, Himanshu Pathak, A.T Padre et al.
The rice-wheat cropping system, occupying 24 million hectares of the productive area in South Asia and China, is important for food security. Monitoring long-term changes in crop yields and identifying the factors associated with such changes are essential to maintain and/or improve crop productivit...
Justina X. Caushi, Jiajia Zhang, Zhicheng Ji, Ajay Vaghasia et al.
Abstract PD-1 blockade unleashes CD8 T cells 1 , including those specific for mutation-associated neoantigens (MANA), but factors in the tumour microenvironment can inhibit these T cell responses. Single-cell transcriptomics have revealed global T cell dysfunction programs in tumour-infiltrating lym...
Sarvajeet Singh Gill, Naser A. Anjum, Mirza Hasanuzzaman, Ritu Gill et al.
Abiotic stresses such as salinity, drought, clilling, heavy metal are the major limiting factors for crop productivity. These stresses induce the overproduction of reactive oxygen species (ROS) which are highly reactive and toxic, which must be minimized to protect the cell from oxidative damage. Th...
Michael J. Thomson, Marjorie De Ocampo, James Egdane, M. Akhlasur Rahman et al.
Abstract This study characterized Pokkali-derived quantitative trait loci (QTLs) for seedling stage salinity tolerance in preparation for use in marker-assisted breeding. An analysis of 100 SSR markers on 140 IR29/Pokkali recombinant inbred lines (RILs) confirmed the location of the Saltol QTL on ch...
Md. Abdus Salam, Md. Yusuf Al-Amin, Moushumi Tabassoom Salam, Jogendra Singh Pawar et al.
Antibiotics are the most magnificent discovery of 20th century that have saved millions of lives from infectious diseases. Microbes have developed acquired antimicrobial resistance (AMR) to many drugs due to high selection pressure from increasing use and misuse of antibiotics over the years. The tr...
Ravi P. Singh, P. K. Singh, Jessica Rutkoski, David Hodson et al.
Wheat is grown worldwide in diverse geographical regions, environments, and production systems. Although many diseases and pests are known to reduce grain yield potential and quality, the three rusts and powdery mildew fungi have historically caused major crop losses and continue to remain economica...
Chandra Giri, Zhiliang Zhu, Larry L. Tieszen, Ajay Singh et al.
Abstract Aim We aimed to estimate the present extent of tsunami‐affected mangrove forests and determine the rates and causes of deforestation from 1975 to 2005. Location Our study region covers the tsunami‐affected coastal areas of Indonesia, Malaysia, Thailand, Burma (Myanmar), Bangladesh, India an...
Willian A. da Silveira, Hossein Fazelinia, Sara Brin Rosenthal, Evagelia C. Laiakis et al.
Spaceflight is known to impose changes on human physiology with unknown molecular etiologies. To reveal these causes, we used a multi-omics, systems biology analytical approach using biomedical profiles from fifty-nine astronauts and data from NASA’s GeneLab derived from hundreds of samples flown in...
Marc Monot, Nadine Honoré, Thierry Garnier, Nora Zidane et al.
Reductive evolution and massive pseudogene formation have shaped the 3.31-Mb genome of Mycobacterium leprae, an unculturable obligate pathogen that causes leprosy in humans. The complete genome sequence of M. leprae strain Br4923 from Brazil was obtained by conventional methods (6x coverage), and Il...