Lilia Bliznashka, Sandhya Chaudhary, Susan M Rattigan, Sheila Isanaka et al.
BACKGROUND: Community-based treatment of acute malnutrition saves lives, but recovered children remain at risk of relapse postdischarge. Strategies to reduce this risk may include modification of anthropometric discharge criteria. OBJECTIVES: This study aims to compare the diagnostic accuracy of ant...
Arjun Chandna, Constantinos Koshiaris, Raman Mahajan, Riris Andono Ahmad et al.
BACKGROUND: Prognostic tools for febrile illnesses are urgently required in resource-constrained community contexts. Circulating immune and endothelial activation markers stratify risk in common childhood infections. We aimed to assess their use in children with febrile illness presenting from rural...
Arjun Chandna, Constantinos Koshiaris, Raman Mahajan, Riris Adono Ahmad et al.
In resource-constrained community settings, identifying which febrile children require referral remains a major unmet need. Current World Health Organization (WHO) danger signs have limited accuracy, resulting in missed severe illness and unnecessary referrals. Here we developed and validated clinic...
Arjun Chandna, Constantinos Koshiaris, Raman Mahajan, Riris Andono Ahmad et al.
ABSTRACT In resource-constrained community settings, distinguishing which febrile children require referral is a major unmet need. Current WHO danger signs lack accuracy, resulting in missed severe illness and unnecessary referrals. We developed and validated simple clinical prediction models using ...
Arjun Chandna, Constantinos Koshiaris, Raman Mahajan, Riris Andono Ahmad et al.
ABSTRACT Background Circulating markers of immune and endothelial activation risk stratify infection syndromes agnostic to disease aetiology. However, their utility in children presenting from the community remains unclear. Methods This study recruited children aged 1-59 months presenting with commu...
Raman Mahajan, Shahwar Kazmi, Krishna Pandey, Amit Harshana et al.
p < 0.0 0 01; r = 0.90, p < 0.0 0 01).Mtb -infected mice treated with MMP inhibitor doxycycline or SB-3CT plus ATT showed significantly improved survival with decreasing trend in brain concentration of MMPs (MMP-9, -8, -3, -12), inflammatory cytokines (TNF, IFN- ) and chemokines (CXCL2, CXCL10, CCL3...
Enam Sikder, Beatriz Valle del Barrio, Wasim Firuz, Rabeya Khatoon et al.