Sudha Sivaram, Gautam Majumdar, Douglas M. Puricelli Perin, Ashrafun Nessa et al.
The reductions in cancer morbidity and mortality afforded by population-based cancer screening programmes have led many low-income and middle-income countries to consider the implementation of national screening programmes in the public sector. Screening at the population level, when planned and org...
Aastha Chugh, Monika Arora, Neha Jain, Aishwarya Lakshmi Vidyasagaran et al.
BACKGROUND: Smokeless tobacco, used by more than 300 million people globally, results in substantial morbidity and mortality. For smokeless tobacco control, many countries have adopted policies beyond the WHO Framework Convention on Tobacco Control, which has been instrumental in reducing smoking pr...
Shamanna S. Iyengar, Raman Puri, S N Narasingan, S K Wangnoo et al.
Shilpa Gunjal, Deepak Gowda Sadashivappa Pateel, Yi‐Hsin Yang, Jennifer Geraldine Doss et al.
Background: Areca nut (AN) and betel quid (BQ) chewing are ancient practices followed by an extensive proportion of the world’s population. These practices are endemic in larger parts of South and Southeast Asia and selected Western Pacific countries. The prevalence of these habits varies across reg...
Jeppe Thagaard, Glenn Broeckx, David B. Page, Chowdhury Arif Jahangir et al.
The clinical significance of the tumor-immune interaction in breast cancer is now established, and tumor-infiltrating lymphocytes (TILs) have emerged as predictive and prognostic biomarkers for patients with triple-negative (estrogen receptor, progesterone receptor, and HER2-negative) breast cancer ...
David B. Page, Glenn Broeckx, Chowdhury Arif Jahangir, Sara Verbandt et al.
Modern histologic imaging platforms coupled with machine learning methods have provided new opportunities to map the spatial distribution of immune cells in the tumor microenvironment. However, there exists no standardized method for describing or analyzing spatial immune cell data, and most reporte...
Sok King Ong, Rei Haruyama, Cheng Har Yip, Tran Thu Ngan et al.
Background: The Global Breast Cancer Initiative (GBCI) Framework, launched by the World Health Organisation (WHO) in 2023, emphasises assessing, strengthening, and scaling up services for the early detection and management of breast cancer. This study aims to determine the feasibility of monitoring ...
Anne Readshaw, Ravi Mehrotra, Masuma Pervin Mishu, Zohaib Khan et al.
ASTRA (Addressing Smokeless Tobacco Use and Building Research Capacity in South Asia) is a new Global Health Research Group funded by the UK’s National Institute for Health Research (NIHR). The aim of ASTRA is to reduce the burden of disease caused by the use of smokeless tobacco in South Asian coun...
Chowdhury Arif Jahangir, David B. Page, Glenn Broeckx, Claudia Aura Gonzalez et al.
Recent advances in the field of immuno-oncology have brought transformative changes in the management of cancer patients. The immune profile of tumours has been found to have key value in predicting disease prognosis and treatment response in various cancers. Multiplex immunohistochemistry and immun...
Monika Arora, Aastha Chugh, Neha Jain, Masuma Pervin Mishu et al.
INTRODUCTION: Smokeless tobacco (ST) was consumed by 356 million people globally in 2017. Recent evidence shows that ST consumption is responsible for an estimated 652 494 all-cause deaths across the globe annually. The WHO Framework Convention on Tobacco Control (FCTC) was negotiated in 2003 and ra...
S M Abdullah, Rumana Huque, Kamran Siddiqi, Mona Kanaan et al.
INTRODUCTION: Illicit smokeless tobacco (ST) trade has seldom been documented despite ST use in at least 127 countries across the world. Based on non-compliance with packaging regulations, we report the proportion of illicit ST products from samples on sale in Bangladesh, India and Pakistan where 85...
Rumana Huque, Zunayed Al Azdi, Aziz Sheikh, Jasjit S. Ahluwalia et al.
Smokeless tobacco (ST) remains poorly regulated in Bangladesh. This study describes the prevalence and trends of ST use in Bangladesh, presents ST-related disease burden, identifies relevant policy gaps, and highlights key implications for future policy and practice for effective ST control in Bangl...
Jonathan Livingstone‐Banks, Aishwarya Lakshmi Vidyasagaran, Ray Croucher, Faraz Siddiqui et al.
RATIONALE: While combustible tobacco has been the subject of a very large amount of research, smokeless tobacco products receive less attention. Most smokeless tobacco products are very harmful and cause global health inequality. It is therefore important to identify evidence-based cessation aids. O...
Sanjay Kalra, Ashok Kumar Das, Sarita Bajaj, Gagan Priya et al.
AIM: The primary objective of this review is to develop a practice-based expert group opinion on the role of precision medicine with a specific focus on sulfonylureas (SUs) in diabetes management. BACKGROUND: The clinical etiology, presentation and complications of diabetes vary from one patient to ...
Faraz Siddiqui, Linda Bauld, Ray Croucher, Cath Jackson et al.
BACKGROUND: Smokeless tobacco (ST) is consumed globally by more than 350 million people, with approximately 85% of all users based in South and Southeast Asia. In this region, ST products are cheap and easily accessible. Evidence-based interventions to people quit ST use are lacking. This study aims...
Kathryn Coyle, Prashant Kumar Singh, Ravi Kaushik, Rumana Huque et al.
INTRODUCTION: Under the current policy landscapes, the lifetime health and economic burden of smokeless tobacco (ST) products, consumed by over 297 million ST users in South Asia, is unknown. The aim of this study was to estimate the lifetime health effects and costs attributable to current and futu...
Sanjay Kalra, Sujoy Ghosh, Ashok Kumar Das, Tiny Nair et al.
AIM: The primary objective of this review is to develop practice-based expert group opinions on the cardiovascular (CV) safety and utility of modern sulfonylureas (SUs) in cardiovascular outcome trials (CVOTs). BACKGROUND: The United States Food and Drug Administration issued new guidance to the pha...
Suzanne Tanya Nethan, Vipin Kumar, Shashi Sharma, Roopa Hariprasad et al.
Background: Oral cancer is the third most common cancer in India which is attributed to the high tobacco burden especially due to a myriad of smokeless tobacco (SLT) products available in the market. Gul/Gul manjan is a commercially-produced, tobacco-based dentifrice, indigenous to rural India and B...
Sneha Joshi, Rupa Mishra, Madhura Kulkarni, Devaki A. Kelkar et al.
On January 13th and 14th 2022, the Center for Translational Cancer Research organized the virtual third Indian Cancer Genome Atlas (ICGA) Conference 2022 "Biobanking to Omics - Collecting the Global Experience." This conference was planned as the steppingstone to help ICGA understand the road ahead ...
Dhirendra Narain Sinha, Shekhar Grover, Harleen Kaur, Chandan Kumar et al.
Background Article 13 of the WHO FCTC provides guidelines for successful enforcement and implementation of effective measures against tobacco advertising, promotion and sponsorship (TAPS). Evidence suggests that TAPS ban reduces tobacco use, especially among young people, while partial bans provide ...