Jeppe Thagaard, Glenn Broeckx, David B. Page, Chowdhury Arif Jahangir et al.
The clinical significance of the tumor-immune interaction in breast cancer is now established, and tumor-infiltrating lymphocytes (TILs) have emerged as predictive and prognostic biomarkers for patients with triple-negative (estrogen receptor, progesterone receptor, and HER2-negative) breast cancer ...
David B. Page, Glenn Broeckx, Chowdhury Arif Jahangir, Sara Verbandt et al.
Modern histologic imaging platforms coupled with machine learning methods have provided new opportunities to map the spatial distribution of immune cells in the tumor microenvironment. However, there exists no standardized method for describing or analyzing spatial immune cell data, and most reporte...
Chowdhury Arif Jahangir, David B. Page, Glenn Broeckx, Claudia Aura Gonzalez et al.
Recent advances in the field of immuno-oncology have brought transformative changes in the management of cancer patients. The immune profile of tumours has been found to have key value in predicting disease prognosis and treatment response in various cancers. Multiplex immunohistochemistry and immun...