Eunüs S. Ali, Kangkana Mitra, Shamima Akter, Sarker Ramproshad et al.
The PI3K-Akt-mechanistic (formerly mammalian) target of the rapamycin (mTOR) signaling pathway is important in a variety of biological activities, including cellular proliferation, survival, metabolism, autophagy, and immunity. Abnormal PI3K-Akt-mTOR signalling activation can promote transformation ...
Eunüs S. Ali, Shamima Akter, Sarker Ramproshad, Banani Mondal et al.
MAPK (mitogen-activated protein kinase) or ERK (extracellular-signal-regulated kinase) pathway is an important link in the transition from extracellular signals to intracellular responses. Because of genetic and epigenetic changes, signaling cascades are altered in a variety of diseases, including c...
Chenmala Karthika, R. Sureshkumar, Mehrukh Zehravi, Rokeya Akter et al.
Even though various treatment methods are available for cancer, the death curve is not reducing. The diagnosis of cancer at the fourth stage and drug resistance are the leading reasons for treatment failure and lower survival rates. In this review article, we summarize the possible pitfalls during c...
Eunüs S. Ali, Brototi Chakrabarty, Sarker Ramproshad, Banani Mondal et al.
Abstract The transient receptor potential melastatin subfamily member 2 (TRPM2), a thermo and reactive oxygen species (ROS) sensitive Ca 2+ -permeable cation channel has a vital role in surviving the cell as well as defending the adaptability of various cell groups during and after oxidative stress....
Malik Ali Ehtsham Awan, Maria Waseem, Areesh Fatima Sahito, Abdul Moiz Sahito et al.
The monkeypox virus, which belongs to the orthopoxy virus family, causes fever, lethargy, headache, lymphadenopathy, myalgia, and rash, as well as various complications such as superimposed infections, sepsis, keratitis, encephalitis, and bronchopneumonia. Following replication at the site of inject...
Uttam Kumar Roy, Chandan Kumar Sarkar, Sarmin Jamaddar, Banani Mondal et al.
Chenmala Karthika, Rokeya Akter, Md. Habibur Rahman, Mehrukh Zehravi et al.
A. N. M. Shofi Uddin, Beton Chakma, Banani Mondal, Sarker Ramproshad et al.
Plants are the major source of therapeutic compounds and have huge applications in Pharma Industry. To identify new sources of therapeutic compounds, we studied acute toxicity, antihyperglycemic, anti-inflammatory, and anticoagulant activities of the polar and nonpolar fractions of Justicia aurea (J...
Md. Rakib Hasan, Milon Mondal, Sherouk Hossein Sweilam, Md. Monir Hossain et al.
Abstract Background Mallotus repandus ( M. repandus ), a well-known medicinal plant, is traditionally used around the globe to treat or prevent numerous diseases and/or disorders such as inflammation, hepatic disorder, cirrhosis, rheumatic arthritis, tumor, and snake-bite. Some common names for it i...
Pritik A Shah, Mohammad Mehedi Hasan, Abdul Moiz Sahito, Suyog Patel et al.
Recently, the World Health Organization (WHO) approved RTS, S/AS01 (RTS, S) as the world's first malaria vaccine for partial malaria protection in young children at risk. While this immunization drive begins during the unprecedented pandemic of the SARS-CoV-2 Virus, the WHO has also approved 7 Vacci...