Talha Bin Emran, Asif Shahriar, Aar Rafi Mahmud, Tanjilur Rahman et al.
Cancer is one of the leading causes of death worldwide. Several treatments are available for cancer treatment, but many treatment methods are ineffective against multidrug-resistant cancer. Multidrug resistance (MDR) represents a major obstacle to effective therapeutic interventions against cancer. ...
Shafiqul Alam Sarker, Shamima Sultana, Gloria Reuteler, D Moine et al.
BACKGROUND: Antibiotic resistance is rising in important bacterial pathogens. Phage therapy (PT), the use of bacterial viruses infecting the pathogen in a species-specific way, is a potential alternative. METHOD: T4-like coliphages or a commercial Russian coliphage product or placebo was orally give...
Stephen P. Luby, Mahmudur Rahman, M. Jahangir Hossain, Lauren S. Blum et al.
We investigated an outbreak of encephalitis in Tangail District, Bangladesh. We defined case-patients as persons from the outbreak area in whom fever developed with new onset of seizures or altered mental status from December 15, 2004, through January 31, 2005. Twelve persons met the definition; 11 ...
Jeanette L. Gehrig, Siddarth Venkatesh, Hao-Wei Chang, Matthew C. Hibberd et al.
To examine the contributions of impaired gut microbial community development to childhood undernutrition, we combined metabolomic and proteomic analyses of plasma samples with metagenomic analyses of fecal samples to characterize the biological state of Bangladeshi children with severe acute malnutr...
Mohammed Mahbubul Matin, Priyanka Matin, Md. Rezaur Rahman, Taïbi Ben Hadda et al.
Among the nitrogen-containing heterocyclic compounds, triazoles emerge with superior pharmacological applications. Structurally, there are two types of five-membered triazoles: 1,2,3-triazole and 1,2,4-triazole. Due to the structural characteristics, both 1,2,3- and 1,2,4-triazoles are able to accom...
Samir K. Saha, Stephanie J. Schrag, Shams El Arifeen, Luke C. Mullany et al.
BACKGROUND: More than 500 000 neonatal deaths per year result from possible serious bacterial infections (pSBIs), but the causes are largely unknown. We investigated the incidence of community-acquired infections caused by specific organisms among neonates in south Asia. METHODS: From 2011 to 2014, ...
Roy Sk, George J. Fuchs, Zeba Mahmud, Gulshan Ara et al.
This prospective randomized trial was carried out to test the efficacy of a specific intervention for reducing the extent of their malnutrition and to change behaviour of mothers relating to child-feeding practices, care-giving, and health-seeking practices under the Bangladesh Integrated Nutrition ...
Saidur Rahman Mashreky, Aminur Rahman, Salim Mahmud Chowdhury, S. Giashuddin et al.
In terms of mortality, morbidity and disability, burns are emerging as a major child health problem in Bangladesh. This trend is similar to many other developing countries. To develop effective burn prevention programmes, information on its magnitude and determinants is necessary. The purpose of thi...
Mehedy Hasan Abir, Tanjilur Rahman, Ayan Das, Silvia Naznin Etu et al.
Marburg virus (MARV) has been a major concern since 1967, with two major outbreaks occurring in 1998 and 2004. Infection from MARV results in severe hemorrhagic fever, causing organ dysfunction and death. Exposure to fruit bats in caves and mines, and human-to-human transmission had major roles in t...
Salek Ahmed Sajib, Mu’tasim Billah, Shafi Mahmud, Masum Miah et al.
Shafi Mahmud, Mohammad Abu Raihan Uddin, Gobindo Kumar Paul, Mst. Sharmin Sultana Shimu et al.
The new coronavirus (SARS-CoV-2) halts the world economy and caused unbearable medical emergency due to high transmission rate and also no effective vaccine and drugs has been developed which brought the world pandemic situations. The main protease (Mpro) of SARS-CoV-2 may act as an effective target...
Aminur Rahman, Saidur Rahman Mashreky, Salim Mahmud Chowdhury, M. S. Giashuddin et al.
OBJECTIVE: To determine the epidemiology of child drowning in order to propose possible interventions for Bangladesh and other similar low-income countries. DESIGN: Population-based cross-sectional study. SETTING: Rural and urban communities in Bangladesh. SUBJECTS: About 352,000 children 0-17 years...
Zulkar Nain, Faruq Abdulla, Mizanur Rahman, Mohammad Minnatul Karim et al.
Elizabethkingia anophelis is an emerging human pathogen causing neonatal meningitis, catheter-associated infections and nosocomial outbreaks with high mortality rates. Besides, they are resistant to most antibiotics used in empirical therapy. In this study, therefore, we used immunoinformatic approa...
Shafi Mahmud, Gobindo Kumar Paul, Mirola Afroze, Shirmin Islam et al.
The recent coronavirus disease 2019 (COVID-19) pandemic is a global threat for healthcare management and the economic system, and effective treatments against the pathogenic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus responsible for this disease have not yet progressed beyond...
Shafi Mahmud, Md. Oliullah Rafi, Gobindo Kumar Paul, Maria Meha Promi et al.
Currently, no approved vaccine is available against the Middle East respiratory syndrome coronavirus (MERS-CoV), which causes severe respiratory disease. The spike glycoprotein is typically considered a suitable target for MERS-CoV vaccine candidates. A computational strategy can be used to design a...