Wei Zhao, Asif Rasheed, Emmi Tikkanen, Jung‐Jin Lee et al.
To evaluate the shared genetic etiology of type 2 diabetes (T2D) and coronary heart disease (CHD), we conducted a genome-wide, multi-ancestry study of genetic variation for both diseases in up to 265,678 subjects for T2D and 260,365 subjects for CHD. We identify 16 previously unreported loci for T2D...
Samir K. Saha, Stephanie J. Schrag, Shams El Arifeen, Luke C. Mullany et al.
BACKGROUND: More than 500 000 neonatal deaths per year result from possible serious bacterial infections (pSBIs), but the causes are largely unknown. We investigated the incidence of community-acquired infections caused by specific organisms among neonates in south Asia. METHODS: From 2011 to 2014, ...
Spencer L James, Lydia R Lucchesi, Catherine Bisignano, Chris D Castle et al.
BACKGROUND: The global burden of road injuries is known to follow complex geographical, temporal and demographic patterns. While health loss from road injuries is a major topic of global importance, there has been no recent comprehensive assessment that includes estimates for every age group, sex an...
Fyezah Jehan, Sunil Sazawal, Abdullah H Baqui, Muhammad Imran Nisar et al.
Importance: Worldwide, preterm birth (PTB) is the single largest cause of deaths in the perinatal and neonatal period and is associated with increased morbidity in young children. The cause of PTB is multifactorial, and the development of generalizable biological models may enable early detection an...
Zahid Hayat Mahmud, Md. Shafiqul Islam, Khan Mohammad Imran, Syed Adnan Ibna Hakim et al.
Abstract Background Safe water is essential for life but unsafe for human consumption if it is contaminated with pathogenic microorganisms. An acceptable quality of water supply (adequate, safe and accessible) must be ensured to all human beings for a healthy life. Methods We collected and analyzed ...
Zahid Hayat Mahmud, Mir Himayet Kabir, Sobur Ali, Md. Moniruzzaman et al.
Introduction: Community-acquired infections due to extended-spectrum beta-lactamase (ESBL) producing Escherichia coli are rising worldwide, resulting in increased morbidity, mortality, and healthcare costs, especially where poor sanitation and inadequate hygienic practices are very common. Objective...
Luisa F. Angeles, Shamim Islam, Jared Aldstadt, Kazi Nazmus Saqeeb et al.
Densely populated countries in Asia, such as Bangladesh, are considered to be major contributors to the increased occurrence of global antimicrobial resistance (AMR). Several factors make low-and middle-income countries vulnerable to increased emergence and spread of AMR in the environment including...
Sheikh Mohammed Shariful Islam, Riaz Uddin, Subasish Das, Syed Imran Ahmed et al.
BACKGROUND: Bangladesh has made substantial progress in improving socioeconomic and health indicators over the past 50 years, but data on national disease burden are scarce. We used data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to estimate the burden of disease...
Josh M. Colston, Benjamin F. Zaitchik, Hamada S. Badr, Eleanor Burnett et al.
Abstract Diarrheal disease, still a major cause of childhood illness, is caused by numerous, diverse infectious microorganisms, which are differentially sensitive to environmental conditions. Enteropathogen‐specific impacts of climate remain underexplored. Results from 15 studies that diagnosed ente...
Farah Naz Qamar, Muhammad Imran Nisar, Farheen Quadri, Sadia Shakoor et al.
We report the clinical findings, epidemiology, and risk factors for moderate-to-severe diarrhea (MSD) associated with Aeromonas species in children 0-59 months of age, from the Global Enteric Multicenter Study, conducted at three sites in south Asia and four sites in sub-Saharan Africa. Children wit...
Syed Imran Ahmed
Although breastfeeding is almost universal in Bangladesh, proper breastfeeding is on the decline due to several factors. To assess the knowledge and practices of mothers regarding breastfeeding, data were collected from 2105 mothers during May-August 1996 in two rural areas of Bangladesh. The findin...
Joel Shyam Klinton, Petra Heitkamp, Aamna Rashid, Bolanle Olusola Faleye et al.
The COVID-19 pandemic has impacted health systems and health programs across the world. For tuberculosis (TB), it is predicted to set back progress by at least twelve years. Public private mix (PPM)has made a vital contribution to reach End TB targets with a ten-fold rise in TB notifications from pr...
Josh M. Colston, Abu Syed Golam Faruque, M Jahangir Hossain, Debasish Saha et al.
Diarrheal disease remains a major cause of childhood mortality and morbidity causing poor health and economic outcomes. In low-resource settings, young children are exposed to numerous risk factors for enteric pathogen transmission within their dwellings, though the relative importance of different ...
Mohammad Enayet Hossain, Rajibur Rahman, Sk. Imran Ali, Md. Muzahidul Islam et al.
BACKGROUND: Noroviruses are the most common cause of epidemic and endemic acute gastroenteritis (AGE) worldwide. The burden of norovirus disease in low-income settings is poorly understood. METHODS: We tested stool samples from children less than 5 years of age with diarrhea who were admitted in a r...
Mahmudul Hasan, Md Sorwer Alam Parvez, Kazi Faizul Azim, Md. Abdus Shukur Imran et al.
Here, drug repurposing and molecular docking were employed to screen approved MPP inhibitors and their derivatives to suggest a specific therapeutic agent for the treatment of COVID-19. The approved MPP inhibitors against HIV and HCV were prioritized, while RNA dependent RNA Polymerase (RdRp) inhibi...