Saifuddin Mahmud, Md. Al-Mustanjid, Farzana Akter, Md Shazzadur Rahman et al.
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), better known as COVID-19, has become a current threat to humanity. The second wave of the SARS-CoV-2 virus has hit many countries, and the confirmed COVID-19 cases are quickly spreading. Therefore, the epidemic is still passing the te...
Saifuddin Mahmud, Wenyu Chen, Meng Han, Hosney Jahan et al.
Accurate identification of drug-target interaction (DTI) is a crucial and challenging task in the drug discovery process, having enormous benefit to the patients and pharmaceutical company. The traditional wet-lab experiments of DTI is expensive, time-consuming, and labor-intensive. Therefore, many ...
Saifuddin Mahmud, Wenyu Chen, Yongsheng Liu, Md. Abdul Awal et al.
Discovering drug-target (protein) interactions (DTIs) is of great significance for researching and developing novel drugs, having a tremendous advantage to pharmaceutical industries and patients. However, the prediction of DTIs using wet-lab experimental methods is generally expensive and time-consu...
Hao Jiang, Yinzhu Chen, Wenyu Guo, Yan Zhang et al.
Light encodes multidimensional information, such as intensity, polarization, and spectrum. Traditional extraction of this light information requires discrete optical components by subdividing the detection area into many “one-to-one” functional pixels. The broadband photodetection of high-dimensiona...
Wenyuan Zhao, Sue S. Chen, Yuanjian Chen, Robert A. Ahokas et al.
Fibrosis of the glomerulus and the tubulointerstitium occurs in patients with hypertension. Studies have shown that renal oxidative stress appears in hypertensive kidney disease. The potential role of oxidative stress in renal fibrogenesis remains to be elucidated. Herein, we tested the hypothesis t...
Saifuddin Mahmud, Wenyu Chen, Hosney Jahan, Yongsheng Liu et al.
Identifying interaction between drug and protein is a crucial challenge in drug discovery, which can lead the researchers to develop novel drug compounds or new target proteins for the existing drugs. The determination of drug–target interactions (DTIs) is an extremely time-consuming, costly, and te...
Jianxiong Zhu, Shanling Ji, Zhihao Ren, Wenyu Wu et al.
Isopropyl alcohol molecules, as a biomarker for anti-virus diagnosis, play a significant role in the area of environmental safety and healthcare relating volatile organic compounds. However, conventional gas molecule detection exhibits dramatic drawbacks, like the strict working conditions of ion mo...
Nayeem Hasan, Md Saiful Islam, Wenyu Chen, Muhammad Ashad Kabir et al.
This paper proposes an encryption-based image watermarking scheme using a combination of second-level discrete wavelet transform (2DWT) and discrete cosine transform (DCT) with an auto extraction feature. The 2DWT has been selected based on the analysis of the trade-off between imperceptibility of t...
Le Wang, Hongsheng Wang, Liangbin Yan, Meiwen Yu et al.
BACKGROUND: than rifampin in murine models of leprosy, but data regarding its effectiveness in preventing leprosy are lacking. METHODS: We conducted a cluster-randomized, controlled trial to investigate whether single-dose rifapentine is effective in preventing leprosy in household contacts of patie...
Jie Ma, Dawei Li, Lin Cheng, Xiaoming Lou et al.
Braess paradox is a well-known paradox in transportation researches. In urban cities, there are many different kinds of complex road networks. Unavoidably, some of them fall into the Braess paradox and it is hardly realized. In this paper, two proposed approaches are applied to find and avoid the Br...
Xiaoqun Yu, Chenfeng Wang, Wenyu Wu, Shuping Xiong
Jie Xu, Yinjie Cui, Jian Guo, Zhengbin Xu et al.
A broadband transition from microstrip line to spoof surface plasmon (SP) waveguide is proposed. The transition transforms the guided wave into a spoof SP polariton in a broad microwave frequency band. A back‐to‐back transition sample is fabricated using the proposed method. Good agreement between t...
Md. Faruk Hosen, Saifuddin Mahmud, Kawsar Ahmed, Wenyu Chen et al.
Accurate identification of DNA-binding proteins (DBPs) is critical for both understanding protein function and drug design. DBPs also play essential roles in different kinds of biological activities such as DNA replication, repair, transcription, and splicing. As experimental identification of DBPs ...
Xuan Liu, Jay R. Turner, Christopher R. Oxford, Jacob McNeill et al.
Global ground-level measurements of elements in ambient particulate matter (PM) can provide valuable information to understand the distribution of dust and trace elements, assess health impacts, and investigate emission sources. We use X-ray fluorescence spectroscopy to characterize the elemental co...
Baojun Wang, Bo Jiang, Lin Du, Wenyuan Chen et al.
Background: Non-responsiveness is a major barrier in current cancer immune checkpoint blockade therapies, and the mechanism has not been elucidated yet. Therefore, it is necessary to discover the mechanism and biomarkers of tumor immunotherapeutic resistance. Methods: T cell infiltration in multiple...