David A. Sack, S. Huda, P K Neogi, R Daniel et al.
We have developed a microtiter enzyme-linked immunosorbent assay method for detecting the heat-labile enterotoxins of Vibrio cholerae and Escherichia coli using GM1 ganglioside as the base coat. This method compares favorably with a similar assay using anticholera toxin as the base coat, and with th...
William M. Spira, Paula J. Fedorka–Cray
Cholera toxin-like (CT-like) enterotoxins produced by two strains of Vibrio mimicus, 61892 and 63616, isolated from diarrhea patients in Bangladesh, were purified, and their physicochemical, biological, and immunological properties were compared with those of CT produced by classical Vibrio cholerae...
William M. Spira, Anwarul Huq, Qazi Shafi Ahmed, Yusuf A. Saeed
Vibrio cholerae biotype eltor appears to concentrate on the surface of the water hyacinth (Eichornia crassipes), thereby enhancing its survival and its potential for transmission through waterways of cholera-endemic regions such as Bangladesh.
Robert H. Gilman, Raija Partanen, Kenneth H. Brown, William M. Spira et al.
To assess the effect of malnutrition on gastric acidity and gastric bacterial colonization, we studied 35 severely malnourished Bangladeshi children before (0 wk) and after (3 wk) they received nutritional rehabilitation for 3 wk. These results were compared with those obtained from a similarly exam...
William M. Spira, M. U. Khan, Yasir Saeed, Abdus Sattar
The apparent failure of handpump tubewells to reduce the incidence of cholera among users in the flooded rural area of Bangladesh has stimulated interest in defining precisely the means of Vibrio cholerae transmission during localized outbreaks. Cholera-infected neighbourhoods were placed under inte...
L A McNicol, Kanwal Aziz, I Huq, James B. Kaper et al.
Antibiotic-resistant strains of Aeromonas hydrophila have been isolated from the natural environment in the Chesapeake Bay and areas surrounding Dacca and the Matlab region of Bangladesh. The Bangladesh strains carried resistance to chloramphenicol, streptomycin, and tetracycline, and 57% of them ha...
William M. Spira, Paula J. Fedorka–Cray
Vibrio mimicus 61892, isolated in 1977 from a case of watery diarrhea in Bangladesh, produces an enterotoxin which possesses activity in Y-1 mouse adrenal cells and in rabbit ileal loops which is identical to the prototype cholera toxin (CT) produced by Vibrio cholerae 569B. The neutralization of th...
William M. Spira, Qazi Shafi Ahmed
Gauze filtration followed by 18-h enrichment in alkaline bile-peptone water is a simple, inexpensive, and efficient method for isolation Vibrio cholerae biotype eltor from contaminated surface waters.
Robert H. Gilman, William M. Spira, H. Rabbani, Waseque Uddin Ahmed et al.
To evaluate a more economical regimen for severe shigella dysentery, treatment with single-dose (SD) ampicillin (100 mg/kg) was compared in a randomized trial with results obtained in a conventional five-day (100 mg/kg per 24 hr) multiple-dose (MD) course. Clinical relapse occurred in one of 23 SD c...
Golam Rabbani, Robert H. Gilman, William M. Spira
L A McNicol, James B. Kaper, Hank Lockman, Elaine F. Remmers et al.
Two group F vibrio organisms have been identified among a collection of vibrio strains isolated from the aquatic environment in Bangladesh. Neither group F strain produced a cholera-like enterotoxin. One of the isolates, BV12, contained an R plasmid conferring resistance to streptomycin and chloramp...
Mengyuan Xiao, Christina C. Williams, Pascal A. Oesch, David Elbaz et al.
We report the discovery of an ultra-massive grand-design red spiral galaxy, named Zhúlóng (Torch Dragon), at z phot = 5.2 −0.2 +0.3 in the JWST PANORAMIC survey; it is the most distant bulge+disk galaxy candidate with spiral arms known to date. Zhúlóng displays an extraordinary combination of proper...
J. WILLIAM WHITE, A. Rodriguez-Aguilar
Summary The climate of the Indo-Gangetic Plains (IGP) is dominated by the Asian summer monsoon. The cool, dry winter is followed by a warming trend with daytime temperatures reaching as high as 45°C in June or July. The temperature rise is broken by the onset of the monsoon rains, when the daytime m...
R. H. Gilman, William M. Spira, Golam Rabbani, A. Al-Mahomod
Journal Article Invasive E. coli and V. parahaemolyticus a rare cause of dysentery in Dacca Get access R. H. Gilman, R. H. Gilman Johns Hopkins University, International Centre for Medical Research, Baltimore City Hospitals, 4940 Eastern Avenue, Baltimore, Maryland, USA Search for other works by thi...