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Results for “"Xue‐Nan Li"”

14 results

Di(2-ethylhexyl) phthalate induced hepatotoxicity in quail (Coturnix japonica) via modulating the mitochondrial unfolded protein response and NRF2 mediated antioxidant defense

Verified

Qi Zhang, Yi Zhao, Milton Talukder, Yu Han et al.

Journal: The Science of The Total EnvironmentYear: 2018Citations: 111

Among ubiquitously found environmental contaminants in the ecosystem, di(2-ethylhexyl) phthalate (DEHP) is an important environmental contaminant used as plasticizer in medical and consumer goods. The bioaccumulation and environmental persistence of DEHP cause serious global health effects in wildli...

Physical SciencesEnvironmental ScienceHealth, Toxicology and Mutagenesis
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Di-2-ethylhexyl phthalate (DEHP) induced lipid metabolism disorder in liver via activating the LXR/SREBP-1c/PPARα/γ and NF-κB signaling pathway

Verified

Yue-Qiang Huang, Yi-Xi Tang, Bai-Hao Qiu, Milton Talukder et al.

Journal: Food and Chemical ToxicologyYear: 2022Citations: 105

Di-2-ethylhexyl phthalate (DEHP) has been widely used in many fields (agricultural products, medical instruments, and food packing). As an environmental contaminant, DEHP has a negative impact on human and animal health, and thus toxicity caused by DEHP is increasingly serious health concern. Nevert...

Health SciencesNursingNutrition and Dietetics
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Lycopene prevents DEHP-induced hepatic oxidative stress damage by crosstalk between AHR–Nrf2 pathway

Verified

Yi Zhao, Rongkun Bao, Shi‐Yong Zhu, Milton Talukder et al.

Journal: Environmental PollutionYear: 2021Citations: 105

Di (2-ethylhexyl) phthalate (DEHP) is a widespread plasticizer that persists in the environment and can significantly contribute to serious health hazards of liver especially oxidative stress injury. Lycopene (LYC) as a carotenoid has recently gained widespread attention because of antioxidant activ...

Physical SciencesEnvironmental ScienceHealth, Toxicology and Mutagenesis
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Crosstalk between unfolded protein response and Nrf2-mediated antioxidant defense in Di-(2-ethylhexyl) phthalate-induced renal injury in quail (Coturnix japonica)

Verified

Yi Zhao, Zheng‐Hai Du, Milton Talukder, Jia Lin et al.

Journal: Environmental PollutionYear: 2018Citations: 75

The widely used Di-(2-ethylhexyl) phthalate (DEHP) has been reported to exhibit ubiquitous environmental and global health hazards. The bioaccumulation and environmental persistence of DEHP can cause serious health hazards in wildlife animals and human. However, DEHP-induced nephrotoxicity in bird i...

Health SciencesNursingNutrition and Dietetics
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Role of mitochondria-endoplasmic reticulum coupling in lycopene preventing DEHP-induced hepatotoxicity

Verified

Yi Zhao, Jia-Gen Cui, Hao Zhang, Xue‐Nan Li et al.

Journal: Food & FunctionYear: 2021Citations: 71

), but LYC alleviated these alterations. Therefore, LYC prevented DEHP-induced hepatic mitochondrial dynamics and MAM disorder, leading to ER stress. The present study provides novel evidence of mitochondria-ER coupling as a target for LYC that prevents DEHP-induced hepatotoxicity.

Health SciencesMedicineBiochemistry
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Di-(2-ethylhexyl) phthalate (DEHP)-induced hepatotoxicity in quail (Coturnix japonica) via suppression of the heat shock response

Verified

Yi Zhao, Jinghui Fan, Yu Luo, Milton Talukder et al.

Journal: ChemosphereYear: 2019Citations: 65

Di-(2-ethylhexyl) phthalate (DEHP) is a widespread environmental toxicant that severely impacts agricultural production and animal and human health. Nevertheless, DEHP-induced hepatotoxicity at the molecular level in quail remains unexplored. The heat shock response (HSR), involving heat shock prote...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Biology
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The FAK/occludin/ZO-1 complex is critical for cadmium-induced testicular damage by disruption of the integrity of the blood-testis barrier in chickens

Verified

Xiaowei Li, Sheng Li, Yu Yang, Milton Talukder et al.

Journal: Journal of Hazardous MaterialsYear: 2024Citations: 36

Cadmium (Cd) is a well-known testis toxicant. The blood-testis barrier (BTB) is a crucial component of the testis. Cd can disrupt the integrity of the BTB and reproductive function. However, the mechanism of Cd-induced disruption of BTB and testicular damage has not been fully elucidated. Here, our ...

Physical SciencesEnvironmental ScienceHealth, Toxicology and Mutagenesis
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Lycopene Protects against Atrazine-Induced Kidney STING-Dependent PANoptosis through Stabilizing mtDNA via Interaction with Sam50/PHB1

Verified

Bao‐Jin Yi, Chi Chiu Wang, Xiao‐Wei Li, Xiao-Wei Li et al.

Journal: Journal of Agricultural and Food ChemistryYear: 2024Citations: 26

Atrazine (ATR) is a widely used herbicide worldwide that can cause kidney damage in humans and animals by accumulation in water and soil. Lycopene (LYC), a carotenoid with numerous biological activities, plays an important role in kidney protection due to its potent antioxidant and anti-inflammatory...

Life SciencesImmunology and MicrobiologyImmunology
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Di (2-ethylhexyl) phthalate induced lipophagy-related renal ferroptosis in quail (Coturnix japonica)

Verified

Yu Zhu, Xiangyu Ma, Ling-Ge Cui, Yaru Xu et al.

Journal: The Science of The Total EnvironmentYear: 2024Citations: 18

Di(2-ethylhexyl) phthalate (DEHP) is a synthetic chemical applied as a plasticizer. As an environmental toxicant, DEHP poses a serious health threat. Many studies have revealed that DEHP can cause lead to various degrees of damage to the kidney. However, the evidence of DEHP-induced renal ferroptosi...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Biology
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Cadmium Transforms Astrocytes into the A1 Subtype via Inducing Gap Junction Protein Connexin 43 into the Nucleus

Verified

Yingxin Zhao, Ying-Xin Zhao, Xue‐Nan Li, Yi-Xi Tang et al.

Journal: Journal of Agricultural and Food ChemistryYear: 2023Citations: 14

Cadmium is highly toxic and present in the environment and can be accumulated among various levels of the food chain. Both humans and animals are at risk from toxicity associated with cadmium. However, the neurological endpoint caused by cadmium has not been revealed. The aim of our research is to e...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Biology
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Selenoprotein W as a molecular target of <scp>d</scp>-amino acid oxidase is regulated by <scp>d</scp>-amino acid in chicken neurons

Verified

Wei Li, Milton Talukder, Xuetong Sun, Cong Zhang et al.

Journal: MetallomicsYear: 2018Citations: 12

Selenoprotein W (SelW) is an important member of the avian selenoprotein family. It is well known for its important role in protecting neurons from oxidative stress during neuronal development. d-Amino acid (d-serine), as a neurotransmitter in the central nervous system (CNS), can mediate neurotoxic...

Life SciencesBiochemistry, Genetics and Molecular BiologyBiochemistry
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Nano‑selenium alleviates cadmium-induced blood-brain barrier destruction by restoring the Wnt7A/β-catenin pathway

Verified

Chenxi Li, Milton Talukder, Zhaoyi Wang, Shi‐Yong Zhu et al.

Journal: The Science of The Total EnvironmentYear: 2024Citations: 9

Selenium (Se), a highly beneficial animal feed additive, exhibits remarkable antioxidant and anti-inflammatory properties. Nano‑selenium (Nano-Se) is an advanced formulation of Se featuring a specialized drug delivery vehicle, with good bioavailability, higher efficacy, and lower toxicity compared t...

Physical SciencesEnvironmental ScienceHealth, Toxicology and Mutagenesis
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The Nrf2/ARE pathway as a potential target to ameliorate atrazine-induced endocrine disruption in granulosa cells

Verified

Xiaowei Li, Kai Guo, Chi Chiu Wang, Yang Yu et al.

Journal: Poultry ScienceYear: 2024Citations: 7

Atrazine (ATR) is widely used worldwide as a commercial herbicide, Diaminochlorotriazine (DACT) is the main metabolite of ATR in the organism. both of them disrupt the production of steroids and induce abnormal reproductive development. The granulosa cells (GCs) are important for growth and reproduc...

Physical SciencesEnvironmental SciencePollutionOpen Access
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Effects of Exogennous Ebr on Physiological And Biochemical Characteristics of Soybean Under Cadmium Stress

Verified

Tingting Xue, Nan Li, Feng He, Jia Liu

Journal: Bangladesh Journal of BotanyYear: 2024Citations: 2

Cadmium (Cd) is one of the highly toxic, non-essential heavy metals that inhibit plant growth and development. The differences in physiological indicators and leaf microstructure between cadmium-tolerant and cadmium-sensitive soybean under Cd stress were studied. The results showed that the photosyn...

Life SciencesAgricultural and Biological SciencesPlant ScienceOpen Access
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