Mahshid Dehghan, Andrew Mente, Xiaohe Zhang, Sumathi Swaminathan et al.
Background The relationship between macronutrients and cardiovascular disease and mortality is controversial. Most available data are from European and North American populations where nutrition excess is more likely, so their applicability to other populations is unclear. Methods The Prospective Ur...
Shiv Kumar Sarin, Ashok Choudhury, Manoj K. Sharma, Rakhi Maiwall et al.
The first consensus report of the working party of the Asian Pacific Association for the Study of the Liver (APASL) set up in 2004 on acute-on-chronic liver failure (ACLF) was published in 2009. With international groups volunteering to join, the “APASL ACLF Research Consortium (AARC)” was formed in...
Victoria Miller, Andrew Mente, Mahshid Dehghan, Sumathy Rangarajan et al.
BACKGROUND The association between intake of fruits, vegetables, and legumes with cardiovascular disease and deaths has been investigated extensively in Europe, the USA, Japan, and China, but little or no data are available from the Middle East, South America, Africa, or south Asia. METHODS We did a...
Justina X. Caushi, Jiajia Zhang, Zhicheng Ji, Ajay Vaghasia et al.
Abstract PD-1 blockade unleashes CD8 T cells 1 , including those specific for mutation-associated neoantigens (MANA), but factors in the tumour microenvironment can inhibit these T cell responses. Single-cell transcriptomics have revealed global T cell dysfunction programs in tumour-infiltrating lym...
Shiv Kumar Sarin, Ashok Choudhury, George Lau, Ming‐Hua Zheng et al.
Background and aims COVID-19 is a dominant pulmonary disease, with multisystem involvement, depending upon comorbidities. Its profile in patients with pre-existing chronic liver disease (CLD) is largely unknown. We studied the liver injury patterns of SARS-Cov-2 in CLD patients, with or without cirr...
Donald S. Gaydon, Balwinder Singh, Enli Wang, Perry Poulton et al.
Resource shortages, driven by climatic, institutional and social changes in many regions of Asia, combined with growing imperatives to increase food production whilst ensuring environmental sustainability, are driving research into modified agricultural practices. Well-tested cropping systems models...
Ole Fröbert, Matthias Götberg, David Erlinge, Zubair Akhtar et al.
Background: Observational and small, randomized studies suggest that influenza vaccine may reduce future cardiovascular events in patients with cardiovascular disease. Methods: We conducted an investigator-initiated, randomized, double-blind trial to compare inactivated influenza vaccine with saline...
Matthew R. Sydes, Melissa Spears, Malcolm D. Mason, Noel W. Clarke et al.
Background: Adding abiraterone acetate with prednisolone (AAP) or docetaxel with prednisolone (DocP) to standard-of-care (SOC) each improved survival in systemic therapy for advanced or metastatic prostate cancer: evaluation of drug efficacy: a multi-arm multi-stage platform randomised controlled pr...
Adrianna Murphy, Benjamin Palafox, Marjan Walli-Attaei, Timothy Powell‐Jackson et al.
Background: Non-communicable diseases (NCDs) are the leading cause of death globally. In 2014, the United Nations committed to reducing premature mortality from NCDs, including by reducing the burden of healthcare costs. Since 2014, the Prospective Urban and Rural Epidemiology (PURE) Study has been ...
APASL ACLF Working Party, Ashok Choudhury, Ankur Jindal, Rakhi Maiwall et al.
Background and aims Acute-on-chronic liver failure (ACLF) is a progressive disease associated with rapid clinical worsening and high mortality. Early prediction of mortality and intervention can improve patient outcomes. We aimed to develop a dynamic prognostic model and compare it with the existing...
Marjan Walli-Attaei, Rasha Khatib, Martin McKee, Scott A. Lear et al.
BACKGROUND: Hypertension is considered the most important risk factor for cardiovascular diseases, but its control is poor worldwide. We aimed to assess the availability and affordability of blood pressure-lowering medicines, and the association with use of these medicines and blood pressure control...
Tahmeed Ahmed, Santhia Ireen, A.M. Shamsir Ahmed, Sabuktagin Rahman et al.
Although child and maternal malnutrition has been reduced in Bangladesh, the prevalence of underweight (weight-for-age z-score <-2) among children aged less than five years is still high (41%). Nearly one-third of women are undernourished with body mass index of <18.5 kg/m2. The prevalence of anaemi...
M. Safiur Rahman, Zia Ahmed, Sirajum Munir Seefat, Rafiul Alam et al.
This research work was focused to evaluate the concentration of heavy metals (i.e., Cr, Pb, Mn, Cu and Fe) in sediment samples collected from the Dhaleshwari River near the area of a newly established tannery industrial estate, Savar, Bangladesh. The heavy metals in sediment samples were ascertained...
Amit Biswas, Md. Reazul Islam, Zahid Sadek Choudhury, Asif Mostafa et al.
The current decades are marked not by the development of new molecules for the cure of various diseases but rather the development of new delivery methods for optimum treatment outcome. Nanomedicine is perhaps playing the biggest role in this concern. Nanomedicine offers numerous advantages over con...
Md. Mhamud Hussen Sifat, Safwat Mukarrama Choudhury, Sajal K. Das, Md. Hafiz Ahamed et al.
The major hindrances in the energy system are ecological consciousness, lack of clean and sustainable energy management, insufficient energy distribution–transmission–optimization, expensive power transfer costs, and increased customer knowledge of energy charges. Thus why, universal access to the g...