Zobaer Al Mahmud, Sitesh Chandra Bachar, Choudhury Mahmood Hasan, Talha Bin Emran et al.
Oleanolic acid (NZ-15), 7 α, 28-olean diol (NZ-38) and Stigmasterol (NZ-14) were isolated from the ethanolic extracts of the roots of Leea macrophylla (Family: Leeaceae) by using chromatographic analysis. This is the first report of isolation of these compounds from this plant. Their structures were...
Zobaer Al Mahmud, Talha Bin Emran, Nazmul Qais, Sitesh Chandra Bachar et al.
BACKGROUND: The objective of this study was to investigate the antinociceptive, anti-inflammatory, thrombolytic and hepatoprotective activities of root extracts of Premna esculenta (family: Verbenaceae). METHODS: The analgesic activity was evaluated using the acetic-acid-induced writhing test in mic...
Amlan Ganguly, Zobaer Al Mahmud, Mir Muhammad Nasir Uddin, SM Abdur Rahman
To screen ethanolic extracts of Manilkara zapota leaves (Family: Sapotaceae) and its different solvent soluble fractions for possible anti-inflammatory, anti-pyretic activities in experimental albino Wistar rats. Anti-inflammatory activity was evaluated by carrageenan induced paw edema method; anti-...
Mir Muhammad Nasir Uddin, Mohammad Shah Hafez Kabir, Mahmud Hasan, Zobaer Al Mahmud et al.
BACKGROUND: The plant under investigation (Tetracera sarmentosa) is a dicotyledonous flowering plant and belongs to the family Dilleniaceae. The goal of our investigation was to determine whether the leaf extracts of this plant held any significant medicinal properties. METHODS: Leaves of T. sarment...
Nisat Sarmin, A. S. M. Roknuzzaman, Tashfiya Zaman Mouree, Md. Rabiul Islam et al.
Recently, scientists have focused on pro-inflammatory cytokines and immunological dysregulation in major depressive disorder (MDD). Some research suggests pro-inflammatory cytokines' role in MDD development, whereas anti-inflammatory studies are sparse. There is no systematic investigation of Bangla...
Zobaer Al Mahmud, SiteshC Bachar, Nazmul Qais, Km Shams‐Ud‐Doha
BACKGROUND: Gomphostemma parviflorum (Lamiaceae) is a medicinal plant of Bangladesh which has been used traditionally in the treatment of painful and inflammatory conditions such as asthma, headache, fever, etc. OBJECTIVE: To investigate the antinociceptive, anti-inflammatory, central nervous system...
Amlan Ganguly, Zobaer Al Mahmud, Sajal Saha, Shibley Rahman
\n\t\t\t\t\tContext Manilkara zapota (L.). P. Royen. (Sapotaceae) has been used in folk medicine to treat pain, diarrhoea, inflammation, arthralgia, and other disorders. Objective Screening of Manilkara zapota leaves ethanol extract and its different solvent soluble fractions for possible antinocice...
Abhijit Sukul, Saikat Kumar Poddar, Sanjana Haque, Sajal Saha et al.
BACKGROUND: Non-steroidal anti-inflammatory drugs (NSAID) exert gastrointestinal upset by inhibiting mucosal cyclooxygenase (COX) activity and complexation technique with metals has been adopted to overcome this drawback. OBJECTIVE: The study aimed to overcome the gastrointestinal side effects assoc...
Jannatul Nayem, Rapty Sarker, A. S. M. Roknuzzaman, M. M. A. Shalahuddin Qusar et al.
BACKGROUND: Major Depressive Disorder (MDD) is a debilitating mental health condition with complex etiology, and recent research has focused on pro-inflammatory cytokines and chemokines as potential contributors to its pathogenesis. However, studies investigating the roles of TNF-α and MCP-4 in MDD ...
Mamun-or-Rashid, A. S. M. Roknuzzaman, Rapty Sarker, Jannatul Nayem et al.
In recent times, the pathogenesis of generalized anxiety disorder (GAD) and the influence of pro- and anti-inflammatory cytokines on it have garnered considerable interest. Cytokine research, especially Th-17 cytokine research on GAD patients, is limited. Here, we aim to assess the role of interleuk...
Shejuti Rahman Brishty, Poushali Saha, Zobaer Al Mahmud, SM Abdur Rahman
The present study describes the synthesis and pharmacological evaluation of a number of substituted benzimidazole derivatives designated by 3A-1, 3A-2, 3A-3, 3B-1 and 3B-2 through condensation of different o-aryldiamine compounds with the corresponding aldehyde employing ammonium salt as a catalyst....
Narhari Das, Durajan Goshwami, Md. Sharif Hasan, Zobaer Al Mahmud et al.
To investigate the antinociceptive, anti-inflammatory and anxiolytic effects of methanolic extracts of Terminalia citrina (T. citrina) leaves (Family: Combretaceae). The antinociceptive activity was evaluated by acetic acid induced writhing method and radiant heat tail flick method while anti-inflam...
Arindom Pal, Zobaer Al Mahmud, Nahia Akter, Saiful Islam et al.
Introduction: The methanolic extracts and its different partitioning fractions of leaves of Clerodendrum indicum were evaluated for their anti-nociceptive, anti-diarrheal and in vitro antimicrobial activities. Methods: The anti-nociceptive activity was evaluated using the acetic acid-induced writhin...
Ramiz Ahmed Sultan, Mohammad Shah Hafez Kabir, Mir Muhammad Nasir Uddin, Mohi Uddin et al.
BACKGROUND: In this ethnopharmacological study, methanolic extract of the aerial plant parts of Phragmites karka (Family: Poaceae) and its petroleum ether and carbon tetrachloride fractions were investigated for bioactivities in Swiss-albino mice, namely, analgesic, central nervous system (CNS) depr...
Nisat Sarmin, A. S. M. Roknuzzaman, Rapty Sarker, Mamun M. Or-Rashid et al.
BACKGROUND: Generalized anxiety disorder (GAD) is a devastating mental health condition characterized by constant, uncontrolled worrying. Recent hypotheses indicate that pro-inflammatory cytokines and chemokines are potential contributors to the pathogenesis of GAD. Here, we aimed to assess the role...
Mahmudul Haque, Hasan Mohammed Saleh Jaashan, Md Zobaer Hasan
Purpose The purpose of this study is to examine Saudi EFL learners’ autonomy beliefs, the relation between their autonomy beliefs and autonomy practices, and the major obstacles against their autonomy.Design/methodology/approach In this quantitative study, a survey questionnaire was administered to ...
Zobaer Al Mahmud, Sitesh Chandra Bachar, Nazmul Qais
Zobaer Al Mahmud, Shazia Ali
A biomedical study was undertaken at the Institute of Nutrition and Food Science, University of Dhaka to observe the effect of the antioxidative roles of vitamins A and E on the degenerative process occurring in spondylosis in human. A single and a double blind study were done. Thirty two patients s...
N. M. Mahmudul Alam Bhuiya, Mahmud Hasan, Zobaer Al Mahmud, Nazmul Qais et al.
Background The objective of the study was to evaluate the antinociceptive, antipyretic and anti-inflammatory activities of ethanolic extract, methanolic extract and n-hexane and chloroform-soluble fractions of methanolic extract of Eria javanica leaves in animal model (rat and mice). Methods The ant...
Farjana Akter, N. M. Mahmudul Alam Bhuiya, Nazmul Hasan, Begum Rokeya et al.
Background and aim: The fruits of Cocos nucifera have long been used in traditional medicine as anti-inflammatory, antimicrobial, antiparasitic, anticancer, and cardiotonic. This study aimed to evaluate the anti-diabetic and antilipidemic activities in the diabetic rat model.Material and methods: Co...