Oral Administration of Probiotic <i>Escherichia coli</i> after Birth Reduces Frequency of Allergies and Repeated Infections Later in Life (after 10 and 20 Years)

BACKGROUND: The development of allergies is a complex in which both composition and influence of the intestinal flora play an important role. We observed in earlier studies that the presence of an orally administered probiotic Escherichia coli strain in the intestine stimulated both a serum and local antibody response, decreased the presence of pathogens, the number of infections and the need for antibiotics. METHODS: The preventive effect of oral colonization after birth with a probiotic E. COLI strain was assessed by evaluating the results of a questionnaire both 20 years (150 full-term infants) and 10 years (77 preterm infants) after colonization. RESULTS: Differences in occurrence of allergies in colonized and control subjects were statistically significant both after 10 and 20…