Classification of Anti-HlyE IgG Responses.

IgG measurements refer to standardized log-transformed fluorescence intensity (see methods). Panels in the top, middle, and bottom rows correspond to the Bangladesh, Malawi, and Nepal study sites, respectively. In each panel, each point represents the anti-HlyE IgG at baseline (x-axis) and the change in IgG from baseline to the follow-up visit (y-axis) of a single participant. <i><i>Left</i></i>: Most participants are clustered around the horizontal dashed line corresponding to no change in IgG between visits. <i><i>Middle</i></i>: Participants are colored by the posterior probability of having a large change (either an increase or decrease) in IgG between visits. This metric is derived from a two-cluster linear regression mixture model. <i><i>Right</i></i>: Participants who experienced a large rise in IgG between visits (posterior probability…