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46+ results
Field: Biochemistry

Nicotinamide riboside is uniquely and orally bioavailable in mice and humans

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Samuel A.J. Trammell, Mark S. Schmidt, Benjamin J. Weidemann, Philip Redpath et al.

Journal: Nature CommunicationsYear: 2016
Citations: 702

Abstract Nicotinamide riboside (NR) is in wide use as an NAD + precursor vitamin. Here we determine the time and dose-dependent effects of NR on blood NAD + metabolism in humans. We report that human blood NAD + can rise as much as 2.7-fold with a single oral dose of NR in a pilot study of one indiv...

Life SciencesBiochemistry, Genetics and Molecular BiologyPhysiologyOpen Access
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In vitro antioxidant and free radical scavenging activity of different parts of Tabebuia pallida growing in Bangladesh

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Md. Mahbubor Rahman, Md. Badrul Islam, Mohitosh Biswas, Aftab Alam

Journal: BMC Research NotesYear: 2015Citations: 652

BACKGROUND: In humans, many diseases are associated with the accumulation of free radicals. Antioxidants can scavenge free radicals and minimize their impact. Therefore, the search for naturally occurring antioxidants of plant origin is imperative. Here, we aimed to investigate the antioxidant and f...

Life SciencesPharmacology, Toxicology and PharmaceuticsToxicologyOpen Access
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Nipah Virus-associated Encephalitis Outbreak, Siliguri, India

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Mandeep Chadha, James A. Comer, Luis Lowe, Paul A. Rota et al.

Journal: Emerging infectious diseasesYear: 2006Citations: 623

During January and February 2001, an outbreak of febrile illness associated with altered sensorium was observed in Siliguri, West Bengal, India. Laboratory investigations at the time of the outbreak did not identify an infectious agent. Because Siliguri is in close proximity to Bangladesh, where out...

Health SciencesMedicineEpidemiologyOpen Access
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Interactive effects of drought and heat stresses on morpho-physiological attributes, yield, nutrient uptake and oxidative status in maize hybrids

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Hafiz Athar Hussain, Shengnan Men, Saddam Hussain, Yinglong Chen et al.

Journal: Scientific ReportsYear: 2019Citations: 621

Abstract Maize is a sensitive crop to drought and heat stresses, particularly at the reproductive stages of development. The present study investigated the individual and interactive effects of drought (50% field capacity) and heat (38 °C/30 °C) stresses on morpho-physiological growth, yield, nutrie...

Life SciencesAgricultural and Biological SciencesAgronomy and Crop ScienceOpen Access
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P-glycoprotein Inhibition for Optimal Drug Delivery

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Md. Lutful Amin

Journal: Drug Target InsightsYear: 2013Citations: 620

P-glycoprotein (P-gp), an efflux membrane transporter, is widely distributed throughout the body and is responsible for limiting cellular uptake and the distribution of xenobiotics and toxic substances. Hundreds of structurally diverse therapeutic agents are substrates to it and it impedes the absor...

Health SciencesMedicineOncologyOpen Access
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Arsenic Accumulation and Metabolism in Rice (<i>Oryza sativa</i> L.)

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Joinal Abedin, Malcolm S. Cresser, Andy A. Meharg, Jörg Feldmann et al.

Journal: Environmental Science & TechnologyYear: 2002Citations: 614

The use of arsenic (As) contaminated groundwater for irrigation of crops has resulted in elevated concentrations of arsenic in agricultural soils in Bangladesh, West Bengal (India), and elsewhere. Paddy rice (Oryza sativa L.) is the main agricultural crop grown in the arsenic-affected areas of Bangl...

Physical SciencesEnvironmental ScienceEnvironmental Chemistry
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Identifying objects by touch: An “expert system”

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Roberta L. Klatzky, Susan J. Lederman, Victoria A. Metzger

Journal: Perception & PsychophysicsYear: 1985Citations: 579
Life SciencesNeuroscienceCognitive NeuroscienceOpen Access
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An extensive study on multiple ETL and HTL layers to design and simulation of high-performance lead-free CsSnCl3-based perovskite solar cells

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M. Khalid Hossain, Gazi Farhan Ishraque Toki, Abdul Kuddus, Mirza H. K. Rubel et al.

Journal: Scientific ReportsYear: 2023Citations: 570

Abstract Cesium tin chloride (CsSnCl 3 ) is a potential and competitive absorber material for lead-free perovskite solar cells (PSCs). The full potential of CsSnCl 3 not yet been realized owing to the possible challenges of defect-free device fabrication, non-optimized alignment of the electron tran...

Physical SciencesEngineeringElectrical and Electronic EngineeringOpen Access
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5-Hydroxymethylfurfural (HMF) levels in honey and other food products: effects on bees and human health

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Ummay Mahfuza Shapla, Md. Solayman, Nadia Alam, Md. Ibrahim Khalil et al.

Journal: Chemistry Central JournalYear: 2018Citations: 568

An organic compound known as 5-hydroxymethylfurfural (HMF) is formed from reducing sugars in honey and various processed foods in acidic environments when they are heated through the Maillard reaction. In addition to processing, storage conditions affect the formation HMF, and HMF has become a suita...

Life SciencesAgricultural and Biological SciencesInsect ScienceOpen Access
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Global Dissemination of <i>Vibrio parahaemolyticus</i> Serotype O3:K6 and Its Serovariants

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G. Balakrish Nair, Thandavarayan Ramamurthy, Sujit Bhattacharya, Basabjit Dutta et al.

Journal: Clinical Microbiology ReviewsYear: 2007Citations: 554

Vibrio parahaemolyticus is recognized as a cause of food-borne gastroenteritis, particularly in the Far East, where raw seafood consumption is high. An unusual increase in admissions of V. parahaemolyticus cases was observed at the Infectious Diseases Hospital in Calcutta, a city in the northeastern...

Life SciencesBiochemistry, Genetics and Molecular BiologyEndocrinologyOpen Access
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Regulation of ROS Metabolism in Plants under Environmental Stress: A Review of Recent Experimental Evidence

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Mirza Hasanuzzaman, M. H. M. Borhannuddin Bhuyan, Khursheda Parvin, Tasnim Farha Bhuiyan et al.

Journal: International Journal of Molecular SciencesYear: 2020Citations: 551

Various environmental stresses singly or in combination generate excess amounts of reactive oxygen species (ROS), leading to oxidative stress and impaired redox homeostasis. Generation of ROS is the obvious outcome of abiotic stresses and is gaining importance not only for their ubiquitous generatio...

Life SciencesAgricultural and Biological SciencesPlant ScienceOpen Access
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Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease

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Paolo Zanoni, Sumeet A. Khetarpal, Daniel B. Larach, William Hancock‐Cerutti et al.

Journal: ScienceYear: 2016Citations: 546

Scavenger receptor BI (SR-BI) is the major receptor for high-density lipoprotein (HDL) cholesterol (HDL-C). In humans, high amounts of HDL-C in plasma are associated with a lower risk of coronary heart disease (CHD). Mice that have depleted Scarb1 (SR-BI knockout mice) have markedly elevated HDL-C l...

Health SciencesMedicineEndocrinology, Diabetes and MetabolismOpen Access
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Glutathione and glutathione reductase: A boon in disguise for plant abiotic stress defense operations

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Sarvajeet Singh Gill, Naser A. Anjum, Mirza Hasanuzzaman, Ritu Gill et al.

Journal: Plant Physiology and BiochemistryYear: 2013Citations: 542

Abiotic stresses such as salinity, drought, clilling, heavy metal are the major limiting factors for crop productivity. These stresses induce the overproduction of reactive oxygen species (ROS) which are highly reactive and toxic, which must be minimized to protect the cell from oxidative damage. Th...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Flavonoids a Bioactive Compound from Medicinal Plants and Its Therapeutic Applications

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Arpita Roy, Ariba Khan, Irfan Ahmad, Saad Alghamdi et al.

Journal: BioMed Research InternationalYear: 2022Citations: 537

Plants generally secrete secondary metabolites in response to stress. These secondary metabolites are very useful for humankind as they possess a wide range of therapeutic activities. Secondary metabolites produced by plants include alkaloids, flavonoids, terpenoids, and steroids. Flavonoids are one...

Health SciencesMedicineBiochemistryOpen Access
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Oral Phage Therapy of Acute Bacterial Diarrhea With Two Coliphage Preparations: A Randomized Trial in Children From Bangladesh

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Shafiqul Alam Sarker, Shamima Sultana, Gloria Reuteler, D Moine et al.

Journal: EBioMedicineYear: 2016Citations: 533

BACKGROUND: Antibiotic resistance is rising in important bacterial pathogens. Phage therapy (PT), the use of bacterial viruses infecting the pathogen in a species-specific way, is a potential alternative. METHOD: T4-like coliphages or a commercial Russian coliphage product or placebo was orally give...

Physical SciencesEnvironmental ScienceEcologyOpen Access
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