Roy Sk, R.H. Behrens, Rukhsana Haider, S. M. Akramuzzaman et al.
Zinc has been shown to enhance intestinal mucosal repair in patients suffering from acrodermatitis enteropathica; but the impact on mucosal integrity during acute (AD) or persistent (PD) diarrhoea is unknown. One hundred eleven children with AD and 190 with PD aged between 3 and 24 months received, ...
Asima Mukhopadhyay, Elizabeth Ruth Plummer, Ahmed Elattar, San Soohoo et al.
Up to 50% of epithelial ovarian cancers (EOC) display defects in the homologous recombination (HR) pathway. We sought to determine the ramifications of the homologous recombination-deficient (HRD) status on the clinicopathologic features, chemotherapy response, and survival outcomes of patients with...
P. S. Hunt, Alastair M. Connell, Tom Smiley
This study was prompted by a clinical association noted between reflux oesophagitis and upper oesophageal disorders. Patients with reflux oesophagitis have been shown to have a significantly raised resting cricopharyngeal pressure. Patients with reflux oesophagitis (36%) complaining of dysphagia loc...
Mark G. O’Doherty, Neal D. Freedman, Albert R. Hollenbeck, Arthur Schatzkin et al.
OBJECTIVE: The incidence of oesophageal adenocarcinoma (EAC) has increased rapidly over the past 40 years and accumulating evidence suggests that obesity, as measured by body mass index (BMI), is a major risk factor. It remains unclear whether abdominal obesity is associated with EAC and gastric ade...
Alexander Schneider, Amitabh Suman, Livio Rossi, M. Michael Barmada et al.
Background & aims Tropical pancreatitis, including tropical calcific pancreatitis and fibrocalculous pancreatic diabetes, is endemic in parts of Asia and Africa. In a preliminary study, we found serine protease inhibitor, Kazal type 1 (SPINK1) mutations in 6 of 8 patients with fibrocalculous pancrea...
Song-Nian Yin, Richard B. Hayes, Martha S. Linet, Guilan Li et al.
A large cohort study of 74,828 benzene-exposed and 35,805 unexposed workers employed between 1972 and 1987 in 12 cities in China were followed to determine mortality from all causes and the incidence of lymphohematopoietic malignancies and other hematologic disorders. Benzene-exposed study subjects ...
Ayesha Molla, Motaher Hossain, S. A. Sarker, W. B. Greenough
124 patients with acute diarrhoea due to Vibrio cholerae or Escherichia coli were treated with either the standard sucrose-electrolyte solution or a cereal-based electrolyte solution, containing 30 g rice powder per litre and electrolytes as recommended by the World Health Organisation. The treatmen...
Cynthia L. Sears, Salequl Islam, Amit Saha, Maleka Arjumand et al.
BACKGROUND: Diarrheal illnesses remain a leading cause of morbidity and mortality globally, with increasing recognition of long-term sequelae, including postinfectious irritable bowel syndrome and growth faltering, as well as cognitive deficits in children. Identification of specific etiologic agent...
J. Richard Pilsner, Xinhua Liu, Habibul Ahsan, Vesna Ilievski et al.
BACKGROUND: Arsenic methylation relies on folate-dependent one-carbon metabolism and facilitates urinary As elimination. Clinical manifestations of As toxicity vary considerably among individuals and populations, and poor methylation capacity is thought to confer greater susceptibility. OBJECTIVE: A...
Anneli Ivarsson, O Hernell, L Nyström, L Å Persson
STUDY OBJECTIVE: Coeliac disease, also called permanent gluten sensitive enteropathy, is being recognised as a widespread health problem. Defining the possible role of environmental factors in its aetiology might open doors to primary prevention. This study therefore analysed if the risk for coeliac...
Kartar Singh
Helicobacter pylori (H pylori) has been etiologically linked to gastric cancer.H pylori infection is more frequent in less developed Asian countries like India, Bangladesh, Pakistan,and Thailand and is acquired at early age than in more developed Asian countries like Japan and China. Frequency of ga...
Shafiqul Alam Sarker, Shamima Sultana, George J. Fuchs, Nur Alam et al.
BACKGROUND: Previous studies have shown that selected strains of lactobacilli that are administered orally result in a modest reduction of diarrhea duration. However, duration alone is not considered optimal for therapeutic evaluation of any agent in diarrhea. OBJECTIVE: To examine the effect of a n...
Peter Speelman, I Kabir, Mohammed Rafiqul Islam
In a study of the distribution and severity of colonic lesions in patients with shigellosis, colonoscopy was performed for 33 men with this disease. All 33 patients had inflammatory lesions in the rectosigmoid area; in 18 (55%) the lesions extended to the splenic flexure, in 14 (42%) the disease ext...
M. M Rahman, Sten H. Vermund, Mohammad A Wahed, G Fuchs et al.
Abstract Objective: To evaluate the effect of simultaneous zinc and vitamin A supplementation on diarrhoea and acute lower respiratory infections in children. Study design: Randomised double blind placebo controlled trial. Setting: Urban slums of Dhaka, Bangladesh. Participants and methods: 800 chil...
W D B Clements, Rowan W. Parks, P Erwin, M I Halliday et al.
BACKGROUND: Gram negative septic events are the commonest source of morbidity and mortality as a result of surgery in jaundiced patients. The large intestine provides the major source of Gram negative bacteria in mammals and is implicated in the pathogenesis of systemic endotoxaemia in obstructive j...