Emranul Kabir, Monir Uzzaman
Heterocyclic compounds have gained a lot of attention because of their numerous significant medical and biological uses. Research interest on heterocyclic compounds is rapidly increasing due to the extensive synthetic study and functional utility. They are found in more than 90% of novel drugs, and ...
Monir Uzzaman, Md. Kamrul Hasan, Shafi Mahmud, Kaniz Fatema et al.
Diclofenac, a nonsteroidal anti-inflammatory drug, is commonly prescribed for the analgesic, antipyretic and anti-inflammation treatment. It is effectively used in acute and chronic pain. It inhibits the prostaglandin synthesis by blocking cyclooxygenase (COX). However, it shows some crucial side ef...
Monir Uzzaman, Md. Kamrul Hasan, Shafi Mahmud, Abu Yousuf et al.
Bisphenols are widely used in polymer and packaging industries. But they are contaminating the environment and food chain by degradation, particularly affecting to the human endocrine system. Herein, we have investigated the physicochemical, spectral, biological and pharmacokinetic properties of som...
Mohammed Mahbubul Matin, Md. Saif Hasan, Monir Uzzaman, M. M. H. Bhuiyan et al.
Regioselective unimolar one-step hexanoylation of methyl α- d -mannopyranoside (MDM) under controlled conditions furnished the 6-O-hexanoate and indicated the regioselectivity at C-6 position. To develop mannopyranoside based potential antimicrobial sugar esters (SEs), 6-O-hexanoate was further conv...
Monir Uzzaman, Tareq Mahmud
Aspirin (Asp) is one of the most important and ancient member of nonsteroidal anti-inflammatory drugs (NSAID), commonly used in medication of fever, pain and inflammation. It can inhibit the synthesis of prostaglandin by blocking the cyclooxygenase (COX). Attempts have been taken to analyze aspirin ...
Monir Uzzaman, Jakaria Shawon, Zainul Abedin Siddique
Mohammed Mahbubul Matin, M. M. H. Bhuiyan, Emranul Kabir, A. F. M. Sanaullah et al.
Methyl α- D -mannopyranoside (MDM, 1) was subjected to direct unimolar lauroylation in pyridine at low temperature (0-20 °C) with lauroyl chloride. It showed regioselectivity at C-6 position and furnished 6-O-lauroyl-α- D -mannopyranoside 3 in 59% yield. For structural elucidation as well as to get ...
Mohammed Mahbubul Matin, Monir Uzzaman, S Chowdhury, M. M. H. Bhuiyan
(1R51). Significant binding affinities were observed against SARS-CoV-2 main protease (7BQY) considering hydroxychloroquine (HCQ) as standard. ADMET predictions were investigated to evaluate their absorption, metabolism and toxic properties. Most of the uridine esters showed better results than that...
Monir Uzzaman, Mohammad Nasir Uddin
Background Ketorolac (KTR) is used as an analgesic drug with an efficacy close to that of the opioid family. It is mainly used for the short term treatment of post-operative pain. It can inhibit the prostaglandin synthesis by blocking cyclooxygenase (COX). Methods In this investigation, the inherent...
Md. Kamrul Hasan, Shamima Akhter, Kaniz Fatema, Md. Rezaul Hossain et al.
Diclofenac (DCF) is a non-steroidal anti-inflammatory drug (NSAID), commonly used for the treatment of pain. It can inhibit prostaglandin synthesis by blocking cyclooxygenase (COX). It shows some crucial side effects like gastrointestinal, cardiovascular, renal, and liver injury. The gastrointestina...
Luthfun Nesa, Shirajum Munira, Shabnam Mollika, Md. Monirul Islam et al.
OBJECTIVES: The study was carried out to assess the analgesic, anti-inflammatory, and CNS depressant activity of the methanolic extract of the Lawsonia inermis barks (MELIB). MATERIALS AND METHODS: Anti-inflammatory effects of MEBLI were studied using carrageenan-induced inflammatory method at the d...
Kaniz Fatema, A. Sharmin, Jinat Fatema Sharna, Md. Anamul Haque et al.
Flemingia macrophylla has traditionally been applied to relieve inflammation, diabetes, and circulatory complications. The leaf extract of F. macrophylla and its fractions were investigated for their in-vitro antioxidant and anti-diabetic properties. The phytochemical screening showed valuable phyto...
Mohammad Nasir Uddin, Zainul Abedin Siddique, Nobuyuki Mase, Monir Uzzaman et al.
A number of oxotitanium(IV) complexes of the type TiOL with bis‐unsymmetric dibasic tetradentate Schiff base (LH 2 ) containing ONNO donor atoms have been synthesized. Mono‐Schiff base (OPD‐HNP) was prepared by the condensation of 1:3 molar ratio of 2‐hydroxy‐1‐naphthaldehyde (HNP) with o ‐phenylene...
Mst. Farhana Afrin, Emranul Kabir, M. R. O. Khan Noyon, Nurjahan Akter et al.
Pesticides are used to control the various pests and disease carriers. Degradation and/or biotransformation alter their chemical and toxicological nature. An attempt has been taken to investigate the physicochemical, spectral, and toxicological nature of DDT [1, 1'-(2, 2, 2-trichloroethylidene) bis(...
Monir Uzzaman, Md. Junaid, Mohammad Nasir Uddin