Bashir Ahmad, Nabia Hafeez, Abdur Rauf, Shumaila Bashir et al.
Medicinal plants are precious gifts of nature, which may serve as a source of food and medicine to humans. Phyllanthus emblica L has held a unique position in the Indian (Ayurvedic), Turkish, Unani, and Tibetan medicinal systems for centuries. Its nutritional, therapeutic and healing potentials have...
Xinda Zou, Amrit BK, Tareq Abu‐Izneid, Ahsan Aziz et al.
Tobacco is grown in large quantities worldwide as a widely distributed commercial crop. From the harvest of the field to the process into the final product, a series of procedures generate enormous amount of waste materials that are rarely recycled. In recent years, numerous potential bioactive comp...
Abdur Rauf, Mohammad Ali Shariati, Muhammad Imran, Kashif Bashir et al.
Though the incidence of several cancers in Western societies is regulated wisely, some cancers such as breast, lung, and colorectal cancer are currently rising in many low- and middle-income countries due to increased risk factors triggered by societal and development problems. Surgery, chemotherapy...
Saikat Mitra, Juhaer Anjum, Maniza Muni, Rajib Das et al.
Emodin is an anthraquinone derivative found in the roots and bark of a variety of plants, molds, and lichens. Emodin has been used as a traditional medication for more than 2000 years and is still common in numerous herbal drugs. Emodin is plentiful in the three plant families, including Polygonacea...
Saima Akhter, Farhin Muntaha Tasnim, Mohammad Nazmul Islam, Abdur Rauf et al.
Background: The IL-17 (interleukin 17) family consists of six structurally related pro-inflammatory cytokines, namely IL-17A to IL-17F. These cytokines have garnered significant scientific interest due to their pivotal role in the pathogenesis of various diseases. Notably, a specific subset of T-cel...
Md. Mominur Rahman, Md. Rezaul Islam, Shopnil Akash, Sheikh Shohag et al.
One of the leading global causes of death is cancer; even though several treatment methods have improved survival rates, the incidence and fatality rates remain high. Naphthoquinones are a type of quinone that is found in nature and has vital biological roles. These chemicals have anticancer (antine...
Md. Sahab Uddin, Md. Farhad Hossain, Abdullah Al Mamun, Muhammad Ajmal Shah et al.
Neurodegeneration is the progressive loss of neuronal structures and functions that lead to copious disorders like Alzheimer's (AD), Parkinson's (PD), Huntington's (HD), amyotrophic lateral sclerosis (ALS), and other less recurring diseases. Aging is the prime culprit for most neurodegenerative even...
Abdur Rauf, Muhammad Akram, Hina Anwar, Muhammad Daniyal et al.
Hyperlipidemia, the most common form of dyslipidemia, is the main source of cardiovascular disorders, characterized by elevated level of total cholesterol (TC), triglycerides (TG) and low-density lipoprotein cholesterol (LDL-C) with high-density lipoprotein cholesterol (HDL-C) in peripheral blood. I...
Chuqi Wang, Minhao Li, Xinyu Duan, Tareq Abu‐Izneid et al.
Tomatoes (Solanum lycopersicum) are of great significance in terms of the worldwide consumption of nutritional diets. More than half of the production is sold as fresh products, while the whole fruit is still typically processed into various products, including canned tomatoes, paste, juice, and pur...
Rajib Das, Abdur Rauf, Saima Akhter, Mohammad Nazmul Islam et al.
Globally, Alzheimer’s disease (AD) is one of the most prevalent age-related neurodegenerative disorders associated with cognitive decline and memory deficits due to beta-amyloid deposition (Aβ) and tau protein hyperphosphorylation. To date, approximately 47 million people worldwide have AD. This fig...
Zineb Hakkou, Alexandre Maciuk, Véronique Leblais, Nour Elhouda Bouanani et al.
Background Inula viscosa L. (Asteraceae) is a medicinal plant widely used as a folk medicine in oriental Morocco, to treat hypertension. The antihypertensive effect of the methanolic extract obtained from I. viscosa leaves was evaluated in hypertensive L-NAME rats. Systolic blood pressure (SBP) was ...
Md. Enamul Huq, Shah Fahad, Zhenfeng Shao, Most. Sinthia Sarven et al.
Drinking water with excessive concentration levels of arsenic (As) is a great threat to human health. A hydrochemical approach was employed in 50 drinking water samples (collected from Kushtia district, Bangladesh) to examine the occurrence of geogenic As and the presence of trace metals (TMs), as w...
Abdullah Al Mamun, Md. Sahab Uddin, Md. Tanvir Kabir, Sayema Khanum et al.
The ubiquitin (Ub)-proteasome system (UPS) is considered as a central protein degradation system in all eukaryotes. The UPS comprises of several factors such as Ub and Ub-like molecules, Ub hydrolases, E3 Ub ligases, and the proteasome itself. Numerous studies have demonstrated that the dysfunction ...
Rasel Ahmed Khan, Rajib Hossain, Pranta Roy, Divya Jain et al.
Cancer, the uncontrolled proliferation and metastasis of abnormal cells, is a major public health issue worldwide. To date, several natural compounds have been reported with their efficacy in the treatment of different types of cancer. Chemotherapeutic agents are used in cancer treatment and prevent...
Md. Mominur Rahman, Xiaoyan Wang, Md. Rezaul Islam, Shopnil Akash et al.
Natural substances originating from plants have long been used to treat neurodegenerative disorders (NDs). Parkinson's disease (PD) is a ND. The deterioration and subsequent cognitive impairments of the midbrain nigral dopaminergic neurons distinguish by this characteristic. Various pathogenic mecha...