Md. Hazrat Ali, Md. Abul Kalam Azad, K. A. Khan, Md. Obaidur Rahman et al.
In this cutting-edge research era, silver nanoparticles impose a substantial impact because of their wide applicability in the field of engineering, science, and industry. Regarding the vast applications of silver nanoparticles, in this study, the crystallographic characteristics and nanostructures ...
Heba E. Hashem, Ashutosh Nath, Ajoy Kumer
Ashutosh Nath, Ajoy Kumer, Fahmida Zaben, Md. Wahab Khan
Abstract Background 2,3-Dihydrobenzofurans (DHB) have proposed as advantages structures, and used as chemical entresol to design small compound libraries. The present study illustrates to explore 2,3-dihydrobenzofurans(DHB) in comparison to selected some derivatives drugs by using molecular docking ...
Md Abdus Samad, Iftikhar Ahmad, A. M. Mahedi Hasan, Mohammad Hassan Alhashmi et al.
Signal transducer and activator of transcription 3 (STAT3) is a critical transcription factor involved in multiple physiological and pathological processes. While STAT3 plays an essential role in homeostasis, its persistent activation has been implicated in the pathogenesis of various diseases, part...
Anupam Kumar Das, Munshi Muhammad Abdul Kader Jilani, Mohammad Shahab Uddin, Md. Aftab Uddin et al.
This study, being explorative, aims to identify the antecedents of social distancing behavior among people in a collective society, in Bangladesh. Based on the social-psychological behavioral model, i.e. theory of planned behavior (TPB), the current study incorporates attitudes, subjective norms, pe...
Sarkar M. A. Kawsar, Ajoy Kumer, Nasrin S. Munia, Mohammed A. Hosen et al.
The methyl -D-glucopyranoside and its derivatives have been estimated as the antimicrobial agents against numerous human pathogens, which is constantly amplifying the attention of medicinal chemists to design new bioactive molecules and their structure-activity relationship (SAR) while the computati...
Ajoy Kumer, Md. Nuruzzaman Sarker, Sunanda Paul
Growing the molecular mechanism of chemicals, thermochemical and biological interactions is considered as the ultimate goal of computational chemistry. Some thermodynamic parameters such as free energy, entropy, dipole moment, binding energy, nuclear energy, electronics energy, heat of formation, an...
Ashutosh Nath, Ajoy Kumer, Md. Wahab Khan
2, 3-Dihydrobenzofuran-2-carboxylates (DHBC) derivatives were synthesized by cyclization on one pot reaction, and characterized by FT-IR, 1H NMR and 13C NMR spectral studies. The intermolecular coupling reactions of 2-iodophenols with acrylic esters by the Pd(Ph3P)2Cl2 catalyst were investigated. Th...
Mohammad Jahidul Islam, Ajoy Kumer, Nuruzzaman Sarker, Sunanda Paul et al.
As the morpholine and morphine have been used all over the world as pain killer drugs even used in cancer treatment, so the morpholine is more demanding chemical molecule. In our work, the morpholine has included the addition of inorganic anions like nitrate and nitrite for forming morpholinium base...
Mohammad Harun‐Ur‐Rashid, Israt Jahan, Md. Jahidul Islam, Ajoy Kumer et al.
Shopnil Akash, Farjana Islam Aovi, AK Azad, Ajoy Kumer et al.
Triple-negative breast cancer (TNBC), accounting for 10-15% of all breast malignancies, is more prevalent in women under 40, particularly in those of African descent or carrying the BRCA1 mutation. TNBC is characterized by the absence of estrogen and progesterone receptors (ER, PR) and low or elevat...
Ajoy Kumer, Nuruzzaman Sarker, Sunanda Paul, Afroza Zannat
Some thermophysical parameters of CBD and THC such as free energy, entropy, dipole moment, binding energy, nuclear energy, electronics energy, heat of formation, and chemical reactivity like HOMO (Occupied Molecular Orbital Highest) and LUMO (Lowest Unoccupied Molecular Orbital, HUMO-LUMO gap, ioniz...
Ajoy Kumer, Md. Wahab Khan
The Brønsted acid-base neutralization was executed for synthesis of the anilinium carboxylate ionic liquids (ACILs), and obtained highly viscous liquids with yields about (90-94)%. These ILs were purified by distillation process and used vacuum oven, as well as characterized by FT-IR, UV spectroscop...
Ajoy Kumer, Md Wahab Khan
Rajiv Chowdhury, Dewan S Alam, Ismail Ibrahim Fakir, Sheikh Daud Adnan et al.
During recent decades, Bangladesh has experienced a rapid epidemiological transition from communicable to non-communicable diseases. Coronary heart disease (CHD), with myocardial infarction (MI) as its main manifestation, is a major cause of death in the country. However, there is limited reliable e...
Ajoy Kumer, Unesco Chakma, Md. Masud Rana, Akhel Chandro et al.
The α-D-glucopyranoside and its derivatives were as the cardinal investigation for developing an effective medication to treat the highest deadly white spot syndrome virus (WSSV) diseases in Shrimp. In our forthcoming work, both computational tools, such as molecular docking, quantum calculations, p...
Heba E. Hashem, Sajjad Ahmad, Ajoy Kumer, Youness El Bakri
Abstract Computer - aided drug design has been employed to get the medicinal effects against Corona virus from different pyridine derivatives after synthesizing the new compounds. Additionally, various computational studies are also employed between the newly prepared pyridine derivatives and three ...
Mahbub Alam, Mohammed Nurul Abser, Ajoy Kumer, M. M. H. Bhuiyan et al.
The thiosemicarbazones and their derivatives have been recognized as antimicrobial agents against human pathogenic bacteria and fungi. Regarding these prospective, this study was designed to address the new antimicrobial agents from thiosemicarbazones and their derivatives. These derivatives were sy...
Ajoy Kumer, Unesco Chakma, Akhel Chandro, Debashis Howlader et al.
Drug discovery and the process of new drug design have been formulated much easier in the past two decades by introducing, proliferation of combined physical, biochemical process from computing capabilities and computational approaches. Since the breast cancer is one of the life-threatening problems...
F. M. Mashood Ahamed, Sampath Chinnam, Malathi Challa, Gurushantha Kariyanna et al.
AbstractStructural modifications of ethyl-3-((5-bromopyridin-2-yl)imino)butanoate ester enhances its biological activities. In the present work, the synthesis of a Schiff base by reacting 2-amino-5-bromo pyridine and ethyl acetoacetate was reported. Electronic properties were investigated by the com...